Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses

Equine Veterinary Journal

Volumn 40, Issue 7, 2008, Pages 662-665

  Germann, S E ^a   Matheis, F L ^a   Rampazzo, A ^a   Burger, D ^b   Roos, M ^a   Spiess, B M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Swiss National Stud Farm   (Switzerland)

Author keywords

Brinzolamide; Carboanhydrase inhibitor; Eye; Glaucoma; Horse; Intraocular pressure

Indexed keywords

BRINZOLAMIDE; CARBONATE DEHYDRATASE INHIBITOR; EYE DROPS; SULFONAMIDE; THIAZINE DERIVATIVE;

ANIMAL; ANIMAL DISEASE; ARTICLE; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECT; FEMALE; GLAUCOMA; HORSE; HORSE DISEASE; INTRAOCULAR PRESSURE; MALE; REFERENCE VALUE; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; CARBONIC ANHYDRASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLAUCOMA; HORSE DISEASES; HORSES; INTRAOCULAR PRESSURE; MALE; OPHTHALMIC SOLUTIONS; REFERENCE VALUES; SULFONAMIDES; THIAZINES;

EQUIDAE;

EID: 55849144730     PISSN: 04251644     EISSN: None     Source Type: Journal    
DOI: 10.2746/042516408X297426     Document Type: Article

References (31)

1. Davidson, H.J., Pinard, C.L., Keil, S.M., Brightman, A.H. and Sargeant, J.M. (2002) Effect of topical ophthalmic latanoprost on intraocular pressure in normal horses. Vet. Ther. 3, 72-80.
2. Derick, R.J. (1994) Glaucoma therapy, section one: Carbonic anhydrase inhibitors. In: Havener's Ocular Pharmacology, 6th edn., Eds: T.F. Mauger and E.J. Craig, Mosby, St Louis. pp 172-180.
3. De Santis, L. (2000) Preclinical overview of brinzolamide. Survey Ophthalmol. 44, 119-129.
4. Fischer, F.H. and Wiederholt, M. (1982) Human precorneal tear film pH measured by microelectrodes. Graefes Arch. Clin. Expt. Ophthalmol. 218, 168-170.
5. Gray, H.E., Willis, A.M. and Morgan, R.V. (2003) Effects of topical administration of 1% brinzolamide on normal cat eyes. Vet. Ophthalmol. 6, 285-290.
6. Gum, G.G., Larocca, R.D. and Gelatt, K.N. (1991) The effect of topical timolol maleate on intraocular pressure in normal beagles and beagles with inherited glaucoma. Prog. vet. Comp. Ophthalmol. 1, 141-149.
7. Hall, R., Havner, G. and Baker, J. (1999) Brinzolamide. In: Analytical Profiles of Drug Substances and Excipients, Ed: H. Brittain, Academic Press, San Diego. pp 47-96.
8. Herkel, U. and Pfeiffer, N. (2001) Update on topical carbonic anhydrase inhibitors. Curr. Opin. Ophthalmol. 12, 88-93.
9. Herring, I.P., Pickett, J.P., Champagne, E.S., Troy, G.C. and Marini, M. (2000) Effect of topical 1% atropine sulfate on intraocular pressure in normal horses. Vet Ophthalmol. 3, 139-143.
10. King, T.C., Gum, G.G. and Gelatt, K.N. (1991) Evaluation of a topically administered carbonic anhydrase inhibitor (MK-927) in normotensive and glaucomatous beagles. Am. J. vet. Res. 52, 2067-2070.
11. Knollinger, A.M., La Croix, N.C., Barrett, P.M. and Miller, P.E. (2005) Evaluation of a rebound tonometer for measuring intraocular pressure in dogs and horses. J. Am. vet. med. Ass. 227, 244-248.
12. Lippa, E.A., Carlson, L.E. and Ehinger, B. (1992) Dose response and duration of action of dorzolamide a topical carbonic anhydrase inhibitor. Arch. Ophthalmol. 110, 495-499.
13. Lowe, R.C. and Crispin, S.M. (2003) Normal equine tear pH as measured with pH paper. In: Programs and Abstracts of the Joint Meeting of BrAVO, ECVO, ESVO, ISVO, Cambridge.
14. Maren, T., Conroy, C., Wynns, G. and Levy, N. (1997) Ocular absorption, blood levels, and excretion of dorzoamide, a topically active carbonic anhydrase inhibitor. J. Ocul. Pharmacol. Ther. 12, 23-30.
15. Mughannam, A.J., Buyukmihci, N.C. and Kass, P.H. (1999) Effect of topical atropine on intraocular pressure and pupil diameter in the normal horse eye. Vet. Ophthalmol. 2, 213-215.
16. Opremcak, E.M. and Weber, P.A. (1985) Interaction of timolol and caffeine on intraocular pressure. J. Ocul. Pharmacol. Ther. 1, 227-234.
17. Sall, K. and Group, B.P.T.S. (2000) The efficacy and safety of brinzolamide 1% ophthalmic suspension (Azopt) as a primary therapy in patients with open angle glaucoma or ocular hypertension. Survey Ophthalmol. 44, 155-162.
18. Silver, L.H. and Group, B.C.S. (2000) Ocular comfort of brinzolamide 1% ophthalmic suspension compared with dorzolamide 2% ophthalmic solution: results from two multicenter comfort studies. Survey Ophthalmol. 44, 141-145.
19. Strahlmann, E.R., Tipping, R. and Vogel, R. (1992) A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol and betaxolol. Arch. Ophthalmol. 113, 1009-1016.
20. Strahlman, E., Tipping, R. and Vogel, R. (1996) A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group. [erratum appears in Am. J. Ophthalmol. (1996) 122, 928]. Am. J. Ophthalmol. 122, 183-194.
21. Sugrue, M.F. (2000) Pharmacological and ocular hypotensive properties of topical carboanhydrase inhibitors. Progr. Retina Eye Res. 19, 87-112.
22. van der Woerdt, A., Gilger, B.C., Wilkie, D.A., Strauch, S.M. and Orczeck, S.M. (1998) Normal variation in, and effect of 2% pilocarpine on, intraocular pressure and pupil size in female horses. Am. J. vet. Res. 59, 1459-1462.
23. van der Woerdt, A., Wilkie, D.A., Gilger, B.C., Strauch, S.M. and Orczeck, S.M. (2000) Effect of single- and multiple-dose 0.5% timolol maleate on intraocular pressure and pupil size in female horses. Vet. Ophthalmol. 3, 165-168.
24. Whelan, N.C., Welch, P., Pace, A. and Brienza, C.A. (1999) A comparison of the efficacy of topical brinzolamide and dorzolamide alone and in combination with oral methazolamide in decreasing normal canine intraocular pressure. In: 30th Annual Meeting of the American College of Veterinary Ophthalmologists. pp 267-268.
25. Wilkerson, M., Cyrlin, M., Lippa, E.A., Esposito, D., Deasy, D., Panebianco, D., Fazio, R., Yablonski, M. and Shields, M.B. (1993) Four-week safety and efficacy study of dorzolamide, a novel, active topical carbonic anhydrase inhibitor. Arch. Ophthalmol. 111, 1343-1350.
26. Wilkie, D.A. and Gilger, B.C. (2004) Equine glaucoma. In: Updates in Ophthalmology, Ed: T.J. Cutler, Elsevier Saunders, Philadelphia. pp 381-391.
27. Wilkie, D.A. and Latimer, C.A. (1991a) Effects of topical administration of timolol maleate on intraocular pressure and pupil size in dogs. Am. J. vet. Res. 52, 432-435.
28. Wilkie, D.A. and Latimer, C.A. (1991b) Effects of topical administration of timolol maleate on intraocular pressure and pupil size in cats. Am. J. vet. Res. 52, 436-440.
29. Willis, A.M., Diehl, K.A. and Robbin, T.E. (2002) Advances in topical glaucoma therapy. Vet. Ophthalmol. 5, 9-17.
30. Willis, A.M., Robbin, T.E., Hoshaw-Woodard, S., Wilkie, D.A. and Schmall, M.L. (2001a) Effect of topical administration of 2% dorzolamide hydrochloride or 2% dorzolamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses. Am. J. vet. Res. 62, 709-713.
31. Willis, A.M., Diehl, K.A., Hoshaw-Woodard, S., Kobayashi, I., Vitucci, M.P. and Schmall, L.M. (2001b) Effects of topical administration of 0.005% latanoprost solution on eyes of clinically normal horses. Am. J. vet. Res. 62, 1945-1951.