Decreased survival and hepato-renal pathology in mice with C-terminally truncated GP73 (GOLPH2)

International Journal of Clinical and Experimental Pathology

Volumn 2, Issue 1, 2009, Pages 34-47

  Wright, Lorinda Marie ^a,b   Yong, Sheri ^a   Picken, Maria Mrozowicz ^a   Rockey, Don ^c   Fimmel, Claus Jüergen ^a,b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Epithelial cells; Glomerulosclerosis; Golgi membrane protein; GP73 (Golph2); Hepatic steatosis; Hyaline thrombi

Indexed keywords

EID: 55849115012     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Kladney RD, Bulla GA, Guo L, Mason AL, Tollefson AE, Simon DJ, Koutoubi Z and Fimmel CJ. GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 2000;249: 53-65.
2. Iftikhar R, Kladney RD, Havlioglu N, Schmitt-Graff A, Gusmirovic I, Solomon H, Luxon BA, Bacon BR and Fimmel CJ. Disease- and cell-specific expression of GP73 in human liver disease. Am J Gastroenterol 2004;99: 1087-1095.
3. Block TM, Comunale MA, Lowman M, Steel LF, Romano PR, Fimmel C, Tennant BC, London WT, Evans AA, Blumberg BS, Dwek RA, Mattu TS and Mehta AS. Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans. Proc Natl Acad Sci USA 2005;102:779-784.
4. Marrero JA, Romano PR, Nikolaeva O, Steel L, Mehta A, Fimmel CJ, Comunale MA, D'Amelio A, Lok AS and Block TM. GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma. J Hepatol 2005;43: 1007-1012.
5. Marrero JA and Lok AS. Newer markers for hepatocellular carcinoma. Gastroenterology 2004;127:S113-S119.
6. Puri S, Bachert C, Fimmel CJ and Linstedt AD. Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption. Traffic 2002;3:641-653.
7. Bachert C, Fimmel C and Linstedt AD. Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma. Traffic 2007;8:1415-1423.
8. Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, Soriano P, Stanford WL, Stryke D, von Melchner H, Wurst W, Yamamura K, Young SG, Babbitt PC and Ferrin TE. The International Gene Trap Consortium website: A portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res 2006;34:D642-D648.
9. Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC and Ferrin TE. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res 2003; 31:278-281.
10. Chomczynski P and Sacchi N. Single step method of RNA isolation by an acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
11. Sunyer T, Lewis J, Collin-Osdoby P and Osdoby P. Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells. J Clin Invest 1999;103: 1409-1418.
12. Looi LM and Loh KC. Microwave-stimulated formaldehyde fixation of experimental renal biopsy tissues: Computerized morphometric analysis of distortion artifacts. Malays J Pathol 2005;27:23-27.
13. Yata Y, Gotwals P, Koteliansky V and Rockey DC. Dose-dependent inhibition of hepatic fibrosis in mice by a TGF-beta soluble receptor: implications for antifibrotic therapy. Hepatology (Baltimore, Md) 2002;35:1022-1030.
14. Kladney RD, Cui X, Bulla GA, Brunt EM and Fimmel CJ. Expression of GP73, a resident Golgi membrane protein, in viral and nonviral liver disease. Hepatology (Baltimore, MD) 2002;35:1431-1440.
15. Wang C, Ivanov A, Chen L, Fredericks WJ, Seto E, Rauscher FJ, 3rd and Chen J. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation. EMBO J 2005;24:3279-3290.
16. Beard M, Satoh A, Shorter J and Warren G. A cryptic Rab1-binding site in the p115 tethering protein. J Biol Chem 2005;280:25840-25848.
17. Chen R, Matthews JH and Jackson AC. Large granular lymphoproliferative disease associated with nephrotic syndrome, renal failure and leukoencephalopathy. Leuk Lymphoma 1993;11:129-133.
18. Calvo Villas JM, Morales Umpierrez A, Ramirez Sanchez MJ and Cuesta Tovar J. Focal and segmental glomerulosclerosis and non-Hodgkin's lymphoma. Clin Nephrol 2002; 57:173-174.
19. Shah S, Cavenagh J, Sheaf M and Thuraisingham RC. Remission of collapsing focal segmental glomerulosclerosis following chemotherapy for myeloma. Am J Kidney Dis 2004;43:e10-12.
20. Jacob CO, Pricop L, Putterman C, Koss MN, Liu Y, Kollaros M, Bixler SA, Ambrose CM, Scott ML and Stohl W. Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF. J Immunol 2006;177: 2671-2680.
21. Mason LJ, Ravirajan CT, Latchman DS and Isenberg DA. A human anti-dsDNA monoclonal antibody caused hyaline thrombi formation in kidneys of 'leaky' SCID mice. Clin Exp Immunol 2001;126:137-142.
22. Daghestani L and Pomeroy C. Renal manifestations of hepatitis C infection. Am J Med 1999;106:347-354.
23. Wharram BL, Goyal M, Wiggins JE, Sanden SK, Hussain S, Filipiak WE, Sauders TL, Dysko RC, Kohno K, Holzman LB and Wiggins RC. Podocyte depletion causes glomerulosclerosis: Diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 2005; 16:2941-2952.
24. Kretzler M. Role of podocytes in focal sclerosis: Defining the point of no return. J Am Soc Nephrol 2005;16:2830-2832.
25. Kretzler M, Koeppen-Hagemann I and Kriz W. Podocyte damage is a critical step in the development of glomerulosclerosis in the uninephrectomised-desoxycorticosterone hypertensive rat. Virchows Arch 1994;425: 181-193.
26. Wiggins JE, Goyal M, Sanden SK, Wharram BL, Shedden KA, Misek DE, Kuick RD and Wiggins RC. Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction. J Am Soc Nephrol 2005;16:2953-2966.
27. Badizaden K and Perez-Atayde AR. Focal glycogenosis of the liver in disorders of ureagenesis: Its occurrence and diagnostic significance. Hepatology (Baltimore, MD) 1997;26:365-373.
28. Quaglia A, Jutand MA, Dhillon A, Godfrey A, Togni R, Bioulac-Sage P, Balabaud C, Winnock M and Dhillon AP. Classification tool for the systematic histological assessment of hepatocellular carcinoma, macroregenerative nodules, and dysplastic nodules in cirrhotic liver. World J Gastroenterol 2005;11:6262-6268.
29. Soyuer I, Ekinci C, Kaya M, Genc Y and Bahar K. Diagnosis of hepatocellular carcioma by fine needle aspiration cytology. Cellular features. Acta Cytol 2003;47:581-589.
30. Abel A, Walcott J, Woods J, Duda J and Merry DE. Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice. Hum Mol Genet 2001;10: 107-116.
31. Bichelmeier U, Schmidt T, Hubener J, Boy J, Ruttiger L, Habig K, Poths S, Bonin M, Knipper M, Schmidt WJ, Wilbertz J, Wolburg H, Laccone F and Riess O. Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. J Neurosci 2007;27: 7418-7428.
32. De Mees C, Laes J-F, Bakker J, Smitz J, Hennuy B, Van Vooren P, Gabant P, Szpirer J and Szpirer C. Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through and antiestrogenic action. Mol Cell Biol 2006;26: 2012-2018.
33. Moggs JG, Ashby J, Tinwell H, Lim FL, Moore DJ, Kimber I and Orphanides G. The need to decide if all estrogens are intrinsically similar. Environ Health Perspect 2004;112:1137-1142.
34. Wang T-T, Tavera-Mendoza LE, Laperriere D, Libby E, MacLeod NB, Nagai Y, Bourdeau V, Konstorum A, Lallemant B, Zhang R, Mader S and White JH. Large-scale in silico an microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol 2005;19:2685-2695.