Quantitative analysis of mouse urine volatiles: In search of MHC-dependent differences

PLoS ONE

Volumn 2, Issue 5, 2007, Pages

  Röck, Frank ^a   Hadeler, Karl Peter ^a   Rammensee, Hans Georg ^a   Overath, Peter ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; DIMETICONE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VOLATILE AGENT; HLA ANTIGEN CLASS 1;

ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; FEMALE; GAS CHROMATOGRAPHY; INBRED STRAIN; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MASS SPECTROMETRY; MOUSE; MOUSE MUTANT; NONHUMAN; ODOR; QUANTITATIVE ANALYSIS; STRAIN DIFFERENCE; URINALYSIS; ANIMAL; GENETICS; MASS FRAGMENTOGRAPHY; MOUSE STRAIN; VOLATILIZATION;

MUS;

ANIMALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; MALE; MICE; MICE, INBRED STRAINS; VOLATILIZATION;

EID: 55849100673     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000429     Document Type: Article

References (39)

1. Thomas L (1975) Symbiosis as an Immunologic Problem. In: Neter E, Milgrom F, eds. The Immune System and Infectious Diseases.. 4th Int. Convoc. Immunol.. BuffaloN.Y., Basel: Karger. pp 2-11.
2. Yamazaki K, Boyse EA, Mike V, Thaler HT, Mathieson BJ, et al. (1976) Control of mating preferences in mice by genes in the major histocompatibility complex. J Exp Med 144: 1324-1335.
3. Yamazaki K, Yamaguchi M, Baranoski L, Bard J, Boyse EA, et al. (1979) Recognition among mice. Evidence from the use of a Y-maze differentially scented by congenic mice of different major histocompatibility types. J Exp Med 150: 755-760.
4. Yamaguchi M, Yamazaki K, Beauchamp GK, Bard J, Thomas L, et al. (1981) Distinctive urinary odors governed by the major histocompatibility locus of the mouse. Proc Natl Acad Sci U S A 78: 5817-5820.
5. Yamazaki K, Beauchamp GK, Egorov IK, Bard J, Thomas L, et al. (1983) Sensory distinction between H-2b and H-2bm1 mutant mice. Proc Natl Acad Sci U S A 80: 5685-5688.
6. Bard J, Yamazaki K, Curran M, Boyse EA, Beauchamp GK (2000) Effect of β2m gene disruption on MHC-determined odortypes. Immunogenetics 51: 514-518.
7. Beauchamp GK, Yamazaki K (2003) Chemical signalling in mice. Biochem Soc Trans 31: 147-151.
8. Yamazaki K, Beauchamp GK (2005) Chemosensory recognition of olfactory individuality. Chem Senses 30(suppl. 1): i142-i143.
9. Wysocki CJ, Yamazaki K, Curran M, Wysocki LM, Beauchamp GK (2004) Mice (Mus musculus) lacking a vomeronasal organ can discriminate MHC-determined odortypes. Horm Behav 46: 241-246.
10. Brown RE, Roser B, Singh PB (1989) Class I and class II regions of the major histocompatibility complex both contribute to individual odors in congenic inbred strains of rats. Behav Genet 19: 659-674.
11. Penn D, Potts WK (1998) Untrained mice discriminate MHC-determined odors. Physiol Behav 53: 235-243.
12. Carroll LS, Penn DJ, Potts WK (2002) Discrimination of MHC-derived odors by untrained mice is consistent with divergence in peptide-binding region residues. Proc Natl Acad Sci U S A 99: 2187-2192.
13. Penn D, Potts W (1998) How do major histocompatibility complex genes influence odor and mating preferences? Adv Immunol 69: 411-435.
14. Spehr M, Kelliher KR, Li X-H, Boehm T, Leiders-Zufall T, et al. (2006) Essential role of the main olfactory system in social recognition of major histocompatibility complex peptide ligands. J Neurosci 26: 1961-1971.
15. Leinders-Zufall T, Brennan P, Widmayer P, Chandramani PS, Maul-Pavicic A, et al. (2004) MHC class I peptides as chemosensory signals in the vomeronasal organ. Science 306: 1033-1037.
16. Boehm T, Zufall F (2006) MHC peptides and the sensory evaluation of genotype. Trends Neurosci 29: 100-107.
17. Montag S, Frank M, Ulmer H, Wernet D, Göpel W, et al. (2001) "Electronic nose" detects major histocompatibility complex-dependent prerenal and postrenal odor components. Proc. Natl Acad Sci U S A 98: 9245-9254.
18. Schaefer ML, Yamazaki K, Osada K, Restrepo D, Beauchamp GK (2002) Olfactory fingerprints for major histocompatibility complex-determined body odors. II: relationship among odor maps, genetics, odor composition, and behavior. J Neurosci 22: 9513-9521.
19. Xu F, Schaefer M, Kida I, Schafer J, Liu N, et al. (2005) Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones. J Comp Neurol 489: 491-500.
20. Schwende FJ, Jorgenson JW, Novotny M (1984) Possible chemical basis for histocompatibilty-related mating preference in mice J Chem Ecol 10: 1603-1615.
21. Singer AG, Beauchamp GK, Yamazaki K (1997) Volatile signals of the major histocompatibility complex in male mouse urine. Proc Natl Acad Sci U S A 94: 2210-2214.
22. Willse A, Belcher AM, Preti G, Wahl JH, Thresher M, et al. (2005) Identification of major histocompatibility complex-regulated body odorants by statistical analysis of a comparative gas chromatography/ mass spectrometry experiment. Analyt Chem 77: 2348-2361.
23. Eggert F, Höller C, Luszyk D, Müller-Ruchholtz W, Ferstl R (1996) MHC-associated and MHC-independent urinary chemosignals in mice. Physiol Behav 59: 57-62.
24. Willse A, Kwack J, Yamazaki K, Preti G, Wahl JH, et al. (2006) Individual odortypes: interaction of MHC and background genes. Immunogenetics 58: 967-982.
25. Novotny MV, Soini HA, Koyama S, Wiesler D, Bruce KE, et al. (2007) Chemical identification of MHC-influenced volatile compounds in mouse urine. I: Quantitative proportions of major chemosignals. J Chem Ecol 33: 417-434.
26. Röck F, Mueller S, Weimar U, Rammensee HG, Overath P (2006) Comparative analysis of volatile constituents from mice and their urine. J Chem Ecol 32: 1333-1346.
27. Koller BH, Marrack P, Kappler JW, Smithies O (1990) Normal development of mice deficient in β2M, MHC class I proteins, and CD8+ T cells. Science 248: 1227-1230.
28. Soini HA, Bruce KE, Wiesler D, David F, Sanda P, et al. (2005) Stir bar sorptive extraction: a new quantitative and comprehensive sampling technique for determination of chemical signal profiles from biological media. J. Chem. Ecol. 31: 377-392.
29. Baltussen E, Cramers CA, Sandra PJF (2002) Sorptive sample preparation - a review Anal Bioanal Chem 373: 3-22.
30. Novotny MV (2003) Pheromones, binding proteins and receptor responses in rodents. Biochem Soc Trans 31: 117-122.
31. Kelliher KR, Ziesmann J, Munger SD, Reed RR, Zufall F (2003) Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice. Proc Natl Acad Sci U S A 100: 4299-4304.
32. Klein J (1982) Immunology, the science of self-nonself discrimination. New York: Wiley & Sons. p 47.
33. Harvey LM, Harvey SJ, Hom M, Perna A, Salib A (2006) The use of bloodhounds in determining the impact of genetics and the environment on the expression of human odortype. J Forensic Sci 51: 1109-1114.
34. Yamazaki K, Beauchamp GK, Bard J, Thomas L, Boyse EA (1982) Chemosensory recognition of phenotypes determined by the Tla and H-2K regions of chromosome 17 of the mouse. Proc Natl Acad Sci U S A 79: 7828-7831.
35. Wedekind C, Penn D (2000) MHC genes, body odours, and odour preferences. Nephrol Dial Transplant 15: 1269-1271.
36. Jacob S, McClintock MK, Zelano B, Ober C (2002) Paternally inherited HLA alleles are associated with women's choice of male odor. Nat Genet 30: 175-179.
37. Santos PSC, Schinemann JA, Gabardo J, da Gracia Bicalho M (2005) New evidence that the MHC influences odor perception in humans: a study with 58 Southern Brazilian students. Horm Behav 47: 384-388.
38. Curran AM, Rabin SI, Prada PA, Furton KG (2005) Comparison of the volatile organic compounds present in human odor using SPME-GC/MS. J Chem Ecol 31: 1607-1619.
39. Penn DJ, Oberzaucher E, Grammer K, Fischer G, Soini HA, et al. (2007) Individual and gender fingerprints in human body odour. J Royal Soc Interface 4: 331-340.