TGF-β1 genotypes in cirrhosis: Relationship with the occurrence of liver cancer

Cytokine

Volumn 44, Issue 2, 2008, Pages 256-261

  Falleti, Edmondo ^a   Fabris, Carlo ^b   Toniutto, Pierluigi ^b   Fontanini, Elisabetta ^a   Cussigh, Annarosa ^a   Bitetto, Davide ^b   Fornasiere, Ezio ^b   Avellini, Claudio ^a   Minisini, Rosalba ^c   Pirisi, Mario ^c  

^a UNIVERSITY OF UDINE   (Italy)

^b DPMSC   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Hepatocellular carcinoma; Liver cirrhosis; Liver transplantation; Transforming growth factor 1; Viral hepatitis

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1; ISOPROTEIN;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BLOOD DONOR; DISEASE ASSOCIATION; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; HUMAN TISSUE; LIVER CANCER; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; IMMUNOLOGY; LIVER TUMOR; MIDDLE AGED;

HEPATITIS C VIRUS;

ADOLESCENT; ADULT; AGED; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; TRANSFORMING GROWTH FACTOR BETA1; YOUNG ADULT;

EID: 55749115971     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2008.08.008     Document Type: Article

References (34)

1. Raza S.A., Clifford G.M., and Franceschi S. Worldwide variation in the relative importance of hepatitis B and hepatitis C viruses in hepatocellular carcinoma: a systematic review. Br J Cancer 96 (2007) 1127-1134
2. Okuda H. Hepatocellular carcinoma development in cirrhosis. Best Pract Res Clin Gastroenterol 21 (2007) 161-173
3. Kiyosawa K., Sodeyama T., Tanaka E., Gibo Y., Yoshizawa K., Nakano Y., et al. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 12 (1990) 671-675
4. Chang M.H., Chen C.J., Lai M.S., Hsu H.M., Wu T.C., Kong M.S., et al. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N Engl J Med 336 (1997) 1855-1859
5. Morgan T.R., Mandayam S., and Jamal M.M. Alcohol and hepatocellular carcinoma. Gastroenterology 127 (2004) S87-S96
6. El-Serag H.B., and Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132 (2007) 2557-2576
7. Blobe G.C., Schiemann W.P., and Lodish H.F. Role of transforming growth factor beta in human disease. N Engl J Med 342 (2000) 1350-1358
8. Matsuzaki K., Murata M., Yoshida K., Sekimoto G., Uemura Y., Sakaida N., et al. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma. Hepatology 46 (2007) 48-57
9. Derynck R., Rhee L., Chen E.Y., and Van Tilburg A. Intron-exon structure of the human transforming growth factor-beta precursor gene. Nucleic Acids Res 15 (1987) 3188-3189
10. Grainger D.J., Heathcote K., Chiano M., Snieder H., Kemp P.R., Metcalfe J.C., et al. Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet 8 (1999) 93-97
11. Gewaltig J., Mangasser-Stephan K., Gartung C., Biesterfeld S., and Gressner A.M. Association of polymorphisms of the transforming growth factor-beta1 gene with the rate of progression of HCV-induced liver fibrosis. Clin Chim Acta 316 (2002) 83-94
12. Tag C.G., Mengsteab S., Hellerbrand C., Lammert F., Gressner A.M., and Weiskirchen R. Analysis of the transforming growth factor-beta1 (TGF-beta1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection. Cytokine 24 (2003) 173-181
13. Barrett S., Collins M., Kenny C., Ryan E., Keane C.O., and Crowe J. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. J Med Virol 71 (2003) 212-218
14. Abbas Z., Moatter T., Hussainy A., and Jafri W. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. World J Gastroenterol 11 (2005) 6656-6661
15. Kwon O.S., Song S.H., Ju K.T., Chung M.G., Park D.K., Kim S.S., et al. Polymorphism in codons 10 and 25 of the transforming growth factor-beta1 gene in Korean population and in patients with liver cirrhosis and hepatocellular carcinoma. Korean J Gastroenterol 42 (2003) 212-219
16. Kim Y.J., Lee H.S., Im J.P., Min B.H., Kim H.D., Jeong J.B., et al. Association of transforming growth factor-beta1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection. Exp Mol Med 35 (2003) 196-202
17. Migita K., Miyazoe S., Maeda Y., Daikoku M., Abiru S., Ueki T., et al. Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection-association between TGF-beta1 polymorphisms and hepatocellular carcinoma. J Hepatol 42 (2005) 505-510
18. Chou H.T., Chen C.H., Tsai C.H., and Tsai F.J. Association between transforming growth factor-beta1 gene C-509T and T869C polymorphisms and rheumatic heart disease. Am Heart J 148 (2004) 181-186
19. Wood N.A., Thomson S.C., Smith R.M., and Bidwell J.L. Identification of human TGF-beta1 signal (leader) sequence polymorphisms by PCR-RFLP. J Immunol Methods 234 (2000) 117-122
20. Stephens M., Smith N.J., and Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68 (2001) 978-989
21. Excoffier L.L.G., and Schneider S. Arlequin ver. 3.0: software package for population genetics data analysis. Evol Bioinform Online 1 (2005) 47-50
22. Crawford S.E., Stellmach V., Murphy-Ullrich J.E., Ribeiro S.M., Lawler J., Hynes R.O., et al. Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell 93 (1998) 1159-1170
23. Khalil N. TGF-beta: from latent to active. Microbes Infect 1 (1999) 1255-1263
24. Su Z.G., Wen F.Q., Feng Y.L., Xiao M., and Wu X.L. Transforming growth factor-beta1 gene polymorphisms associated with chronic obstructive pulmonary disease in Chinese population. Acta Pharmacol Sin 26 (2005) 714-720
25. Bissell D.M. Chronic liver injury, TGF-beta, and cancer. Exp Mol Med 33 (2001) 179-190
26. Bataller R., and Brenner D.A. Liver fibrosis. J Clin Invest 115 (2005) 209-218
27. Kopp J.B., Factor V.M., Mozes M., Nagy P., Sanderson N., Bottinger E.P., et al. Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease. Lab Invest 74 (1996) 991-1003
28. Taniguchi H., Kato N., Otsuka M., Goto T., Yoshida H., Shiratori Y., et al. Hepatitis C virus core protein upregulates transforming growth factor-beta 1 transcription. J Med Virol 72 (2004) 52-59
29. Kimura T., Saito T., Yoshimura M., Yixuan S., Baba M., Ji G., et al. Association of transforming growth factor-beta 1 functional polymorphisms with natural clearance of hepatitis C virus. J Infect Dis 193 (2006) 1371-1374
30. Osterreicher C.H., Datz C., Stickel F., Hellerbrand C., Penz M., Hofer H., et al. TGF-beta1 codon 25 gene polymorphism is associated with cirrhosis in patients with hereditary hemochromatosis. Cytokine 31 (2005) 142-148
31. Tang B., Bottinger E.P., Jakowlew S.B., Bagnall K.M., Mariano J., Anver M.R., et al. Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. Nat Med 4 (1998) 802-807
32. Pierce Jr. D.F., Gorska A.E., Chytil A., Meise K.S., Page D.L., Coffey Jr. R.J., et al. Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proc Natl Acad Sci USA 92 (1995) 4254-4258
33. Kim S.J., and Letterio J. Transforming growth factor-beta signaling in normal and malignant hematopoiesis. Leukemia 17 (2003) 1731-1737
34. Cordenonsi M., Montagner M., Adorno M., Zacchigna L., Martello G., Mamidi A., et al. Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation. Science 315 (2007) 840-843