Rapid production of a plasmid DNA encoding a malaria vaccine candidate via amino-functionalized poly(GMA-co-EDMA) monolith

AIChE Journal

Volumn 54, Issue 11, 2008, Pages 2990-2998

  Danquah, Michael K ^a   Liu, Shan ^a   Ho, Jenny ^a   Forde, Gareth M ^a   Wang, Lina ^a   Coppel, Ross L ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Liquid chromatography; Malaria vaccine; Methacrylate monolith; Plasmid DNA

Indexed keywords

ABS RESINS; ADSORPTION; AMINATION; AMINES; CHROMATOGRAPHIC ANALYSIS; COST EFFECTIVENESS; DNA; GENES; LIQUID CHROMATOGRAPHY; NUCLEIC ACIDS; ORGANIC ACIDS; PROCESS ENGINEERING; PURIFICATION; RNA;

AMBIENT TEMPERATURES; AMINO GROUPS; FUNCTIONALIZED; GLOBAL HEALTHS; INFRA STRUCTURES; MACROPOROUS MATERIALS; MALARIA VACCINE; MALARIA VACCINES; METHACRYLATE MONOLITH; MONOLITHIC POLYMERS; PHYSICAL CHARACTERIZATIONS; PLASMID DNA; PLASMID DNA (PDNA); PLASMID DNAS; PORE DIAMETERS; PROCESSING TIMES; PROTEIN LEVELS; PURIFICATION TECHNIQUES; REGULATORY STANDARDS; STATIONARY PHASE; SUPERCOILED;

VACCINES;

EID: 55749105523     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.11595     Document Type: Article

References (24)

1. Dunachie SA. Prime-boost strategies for malaria vaccine development. J Exp Biol. 2003;206:3771-3779.
2. Gallup JL, Sachs JD. The economic burden of malaria. Am J Trop Med Hyg. 2001:64:85-96.
3. Kumar S, Epstein JE, Richie TL, Nkrumah FK, Soisson L, Carucci DJ, Hoffman SL. A multilateral effort to develop DNA vaccines against falciparum malaria. Trends Parasitai. 2002;18:129-135
4. Moore AC, Hill AV. Progress in DNA-based heterologous primeboost immunization strategies for malaria, Immunol Rev. 2004; 199:126-143.
5. Scorza T, Grubb K, Smooker P, Rainczuk A, Proll D, Spithill TW. Induction of strain-transcending immunity against Plasmodium chabaudi adami malaria with a multiepitope DNA vaccine. Infect Immun. 2005;73(5):2974-2985.
6. th Oct 2007,www.who.int/mediacentre/factsheets/fs094/en/.
7. Nabel GJ, Nabel EG, Yang Z, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct Gene Transfer with DNA-Liposome Complexes in Melanoma: Expression, Biologic Activity, and Lack of Toxicity in Humans. Proceedings of the National Academy of Sciences. 1993:90:11307-11311.
8. Levy MS, O'Kennedy RD, Ayazi-Shamlou P, Dunnill P. Biochemical engineering approaches to the challenges of producing pure plasmid DNA. Trends in Biotechnol. 2000;18:296-305.
9. Danquah MK, Forde GM. Towards the design of a scalable and commercially viable technique for plasmid purification using a methacrylate monolithic stationary phase. J Chem Technol Biotechnol. 2007:82:752-757.
10. Durland R, Eastman E. Manufacturing and quality control of plasmid-based gene expression systems. Adv Drug Deliver. 1998:30:33-48.
11. Diogo MM, Queiroz JA, Prazeres DMF. Chromatography of plasmid DNA. J Chramatogr A. 2005;1069:3-22.
12. Prazeres DMF, Schluep T, Cooney C. Preparative purification of supercoiled plasmid DNA using anion exchange Chromatography. / Chromatogr A. 1998;806:31-45.
13. Danquah MK, Forde GM. The suitability of DEAE-Cl active groups on customized poly(GMA-co-EDMA) continuous stationary phase for fast enzyme-free isolation of plasmid DNA. J Chromatogr B. 2007;853(1-2):38-46.
14. Svec F. Recent developments in LC column technology. LC-GC Europe. 2003;16(6a):24-28.
15. Jungbauer A, Hahn R. Monolith for fast bioseparation, bioconversion and their applications in biotechnology. J Sep Sci. 2004:27:767-778.
16. Zochling A, Hahn R, Ahrer K, Urthaler J, Jungbauer A. Mass transfer characteristics of plasmids in monoliths. J Sep Sci. 2004;27:819-827.
17. Podgornik A, Jancar J, Merhar M, Kozamernik S, Glover D, Cucek K, Barut M, Strancar A. Large-scale monolithic columns: design and properties. J Biochem Biophys Methods. 2004:60:179-189.
18. Wen J, Guillo C, Ferrance JP. DNA extraction using a tetramethyl orthosilicate-grafted photopolymerized monolithic solid phase. J Anal Chem. 2006;78(5);1673-1681.
19. Marshall VM, Silva A, Foley M, Cranmer S, Wang L, McColl DJ, Kemp DJ, Coppel RL. A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factorlike domain. Infect Immun. 1997;65(11);4460-4467.
20. Marshall VM, Tieqiao W, Coppel RL. Close linkage of three merozoite surface protein genes on chromosome 2 of Plasmodium falciparum. Mol Biochem Parasitol. 1998:94(1):13-25.
21. Kedzierski L, Black CG, Coppel RL. Characterisation of the merozoite surface protein 4/5 gene of Plasmodium berghei and Plasmodium yoelii. Mol Biochem Parasitol 2000;105:137-147.
22. Kedzierski L, Black CG, Coppel RL. Immunization with recombinant Plasmodium yoelii merozoite surface protein 4/5 protects mice against lethal challenge. Infect Immun. 2000;68(10):6034-6037.
23. Rainczuk A, Smooker PM, Kedzierski L, Black CG, Coppel RL, Spithill TW. The protective efficacy of MSP4/5 against lethal Plasmodium chabaudi adami challenge is dependent on the type of DNA vaccine vector and vaccination protocol. Vaccine. 2003:21(21-22):3030-3042.
24. Wang L, Kedzierski L, Schofield L, Coppel RL. Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5. Vaccine. 2005;23:4120-4127.