Final height in Swedish children with idiopathic growth hormone deficiency enrolled in KIGS treated optimally with growth hormone

Acta Paediatrica, International Journal of Paediatrics

Volumn 97, Issue 12, 2008, Pages 1698-1706

  Westphal, Otto ^a,c   Lindberg, Anders ^b  

^a SAHLGRENSKA ACADEMY AT UNIVERSITY OF GOTHENBURG   (Sweden)

^b PFIZER INC   (United States)

^c QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

Author keywords

Disproportionality; Final height; Growth hormone deficiency; Growth hormone treatment; Pfizer international growth database

Indexed keywords

HUMAN GROWTH HORMONE; RECOMBINANT GROWTH HORMONE;

ARTICLE; BODY HEIGHT; DATA BASE; DISEASE SEVERITY; GROWTH HORMONE DEFICIENCY; HUMAN; PARENT; PRIORITY JOURNAL; PUBERTY; SHORT STATURE; SUBSTITUTION THERAPY; SWEDEN; TREATMENT OUTCOME;

ADOLESCENT; AGE FACTORS; BODY HEIGHT; CHILD; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GROWTH DISORDERS; HUMAN GROWTH HORMONE; HUMANS; MALE; PHARMACOEPIDEMIOLOGY; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SWEDEN; TREATMENT OUTCOME;

EID: 55749085607     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2008.01053.x     Document Type: Article

References (28)

1. Chatelain P. Trends in the diagnosis and treatment of short stature as revlaled by KIGS. In : Ranke MB, Wilton P, editors. Growth hormone therapy in KIGS-10 years' experience. Heidelberg-Leipzig : Johann Ambrosius Barth Verlag 1999 : 11 20.
2. Dattani MT. Growth hormone deficiency and combined pituitary hormone deficiency: does the genotype matter? Clin Endocrinol 2005 63 : 121 30.
3. Pfäffle RW, DiMattia GE, Parks JS, Brown MR, Wit JM, Jansen M, et al. Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia. Science 1992 257 : 1118 21.
4. Procter AM, Phillips JA, 3rd., Cooper DN. The molecular genetics of growth hormone deficiency. Hum Genet 1998 103 : 255 72.
5. August GP, Julius JR, Blethen SL. Adult height in children with growth hormone deficiency who are treated with biosynthetic growth hormone: the National Cooperative Growth Study experience. Pediatrics 1998 102 : 512 6.
6. Blethen SL, Baptista J, Kuntze J, Foley T, LaFranchi S, Johanson A. Adult height in growth hormone (GH)-deficient children treated with biosynthetic GH. The Genentech Growth Study Group. J Clin Endocrinol Metab 1997 82 : 418 20.
7. Brämswig JH, Schlösser H, Kiese K. Final height in children with growth hormone deficiency. Horm Res 1995 43 : 126 8.
8. Cutfield W, Lindberg A, Albertsson Wikland K, Chatelain P, Ranke MB, Wilton P. Final height in idiopathic growth hormone deficiency: the KIGS experience. KIGS International Board. Acta Paediatr Suppl 1999 88 : 72 5.
9. Frindik JP, Baptista J. Adult height in growth hormone deficiency: historical perspective and examples from the national cooperative growth study. Pediatrics 1999 104 : 1000 4.
10. Bourguignon JP, Vandeweghe M, Vanderschueren- Lodeweyckx M, Malvaux P, Wolter R, Du Caju M, et al. Pubertal growth and final height in hypopituitary boys: a minor role of bone age at onset of puberty. J Clin Endocrinol Metab 1986 63 : 376 82.
11. Carel JC, Ecosse E, Nicolino M, Tauber M, Leger J, Cabrol S, et al. Adult height after long term treatment with recombinant growth hormone for idiopathic isolated growth hormone deficiency: observational follow up study of the French population based registry. BMJ 2002 325 : 70 6.
12. Coste J, Letrait M, Carel JC, Tresca JP, Chatelain P, Rochiccioli P, et al. Long-term results of growth hormone treatment in France in children of short stature: population, register based study. BMJ 1997 315 : 708 13.
13. Hibi I, Tanaka T. Final height of patients with idiopathic growth hormone deficiency after long-term growth hormone treatment. Committee for Treatment of Growth Hormone Deficient Children, Growth Science Foundation, Japan. Acta Endocrinol 1989 120 : 409 15.
14. Wit JM, Kamp GA, Rikken B. Spontaneous growth and response to growth hormone treatment in children with growth hormone deficiency and idiopathic short stature. Pediatr Res 1996 39 : 295 302.
15. Karlberg P, Taranger J. The somatic development of children in a swedish urban community. Acta Paediatr Scand Suppl 1976 : 1 148.
16. Ranke MB, Price DA, Albertsson-Wikland K, Maes M, Lindberg A. Factors determining pubertal growth and final height in growth hormone treatment of idiopathic growth hormone deficiency. Analysis of 195 Patients of the Kabi Pharmacia International Growth Study. Horm Res 1997 48 : 62 71.
17. Gerver WJM, De Bruin R. Paediatric Morphometrics, 1996. Wetenschappelijke uitgeverij Bunge. Utrecht, The Netherlands.
18. Bocca G, Bruin N, Delemarre-van de Waal HA. Gonadotropin releasing hormone analogue therapy in children with isolated growth hormone deficiency: final height benefit from postponing puberty? J Pediatr Endocrinol Metab 2005 18 : 535 9.
19. Hintz RL. Final height of growth hormone-treated patients with growth hormone deficiency: the North American experience. Acta Paediatr Suppl 1999 88 : 70 1.
20. Karavanaki K, Kontaxaki C, Maniati-Christidi M, Petrou V, Dacou-Voutetakis C. Growth response, pubertal growth and final height in Greek children with growth hormone (GH) deficiency on long-term GH therapy and factors affecting outcome. J Pediatr Endocrinol Metab 2001 14 : 397 405.
21. Mericq MV, Eggers M, Avila A, Cutler GB, Jr., Cassorla F. Near-final height in pubertal growth hormone (GH)-deficient patients treated with GH alone or in combination with luteinizing hormone-releasing hormone analog: results of a prospective, randomized trial. J Clin Endocrinol Metab 2000 85 : 569 73.
22. Mul D, Wit JM, Oostdijk W, Van Den Broeck J. The effect of pubertal delay by GnRH agonist in GH-deficient children on final height. J Clin Endocrinol Metab 2001 86 : 4655 6.
23. Ranke MB, Lindberg A, Chatelain P, Wilton P, Cutfield W, Albertsson-Wikland K, et al. Derivation and validation of a mathematical model for predicting the response to exogenous recombinant human growth hormone (GH) in prepubertal children with idiopathic GH deficiency. KIGS International Board. Kabi Pharmacia International Growth Study. J Clin Endocrinol Metab 1999 84 : 1174 83.
24. Reiter EO, Price DA, Wilton P, Albertsson-Wikland K, Ranke MB. Effect of growth hormone (GH) treatment on the final height of 1258 patients with idiopathic GH deficiency: Analysis of a Large International Database. J Clin Endocrinol Metab 2006 91 : 2047 2054.
25. Thomas M, Massa G, Bourguignon JP, Craen M, De Schepper J, de Zegher F, et al. Final height in children with idiopathic growth hormone deficiency treated with recombinant human growth hormone: the Belgian experience. Horm Res 2001 55 : 88 94.
26. De Luca F, Maghnie M, Arrigo T, Lombardo F, Messina MF, Bernasconi S. Final height outcome of growth hormone-deficient patients treated since less than five years of age. Acta Paediatr 1996 85 : 1167 71.
27. Mauras N, Attie KM, Reiter EO, Saenger P, Baptista J. High dose recombinant human growth hormone (GH) treatment of GH-deficient patients in puberty increases near-final height: a randomized, multicenter trial. Genentech, Inc., Cooperative Study Group. J Clin Endocrinol Metab 2000 85 : 3653 60.
28. Albertsson-Wikland K, Rosberg S. Methods of evaluating spontaneous growth hormone secretion. In : Ranke M, editor. Functional Endocrinologic Diagnostics in Children and Adolescents. 3rd ed. J & J Verlag : Mannheim 2003 : pp. 129 59.