Structural basis of cargo membrane protein discrimination by the human COPII coat machinery

EMBO Journal

Volumn 27, Issue 21, 2008, Pages 2918-2928

  Mancias, Joseph D ^a   Goldberg, Jonathan ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

COPII coat; Transport signal; Vesicular transport

Indexed keywords

COAT PROTEIN COMPLEX II; GLYCOPROTEIN; MEMBRANE PROTEIN; MEMBRIN; PROTEIN SUBUNIT; SYNTAXIN 5; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BIOCHEMISTRY; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; ENDOPLASMIC RETICULUM; FEMALE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SURFACE PROPERTY; TRANSPORT VESICLE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CONSERVED SEQUENCE; COP-COATED VESICLES; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; QA-SNARE PROTEINS; QB-SNARE PROTEINS; VESICULAR TRANSPORT PROTEINS;

MAMMALIA; VESICULAR STOMATITIS VIRUS;

EID: 55549137036     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.208     Document Type: Article

References (21)

1. Bi X, Corpina RA, Goldberg J (2002) Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat. Nature 419: 271-277
2. Bi X, Mancias JD, Goldberg J (2007) Insights into COPII coat nucleation from the structure of Sec23·Sar1 complexed with the active fragment of Sec31. Dev Cell 13: 635-645
3. Bock JB, Matern HT, Peden AA, Scheller RH (2001) A genomic perspective on membrane compartment organization. Nature 409: 839-841
4. Bonifacino JS, Glick BS (2004) The mechanisms of vesicle budding and fusion. Cell 116: 153-166
5. Bracher A, Weissenhorn W (2002) Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p. EMBO J 21: 6114-6124
6. Brünger AT (1998) Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54: 905-921
7. Fath S, Mancias JD, Bi X, Goldberg J (2007) Structure and organization of coat proteins in the COPII cage. Cell 129: 1325-1336
8. Fromme JC, Orci L, Schekman R (2008) Coordination of COPII vesicle trafficking by Sec23. Trends Cell Biol 18: 330-336
9. Kim J, Hamamoto S, Ravazzola M, Orci L, Schekman R (2005) Uncoupled packaging of amyloid precursor protein and presenilin 1 into coat protein complex II vesicles. J Biol Chem 280: 7758-7768
10. Lee MC, Miller EA, Goldberg J, Orci L, Schekman R (2004) Bidirectional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol 20: 87-123
11. Mancias J, Goldberg J (2007) The transport signal on Sec22 or packaging into COPII-coated vesicles is a conformational epitope. Mol Cell 26: 403-411
12. McCoy AJ, Grosse-Kunstleve RW, Storoni LC, Adams PD, Read RJ (2007) PHASER crystallographic software. J Appl Crystallogr 40: 658-674
13. Miller E, Antonny B, Hamamoto S, Schekman R (2002) Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J 21: 6105-6113
14. Miller E, Liu Y, Barlowe C, Schekman R (2005) ER-Golgi transport defects are associated with mutation in the Sed5p-binding domain of the COPII coat subunit Sec24p. Mol Biol Cell 16: 3719-3726
15. Miller EA, Beilharz TH, Malkus PN, Lee MC, Hamamoto S, Orci L, Schekman R (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114: 497-509
16. Mossessova E, Bickford LC, Goldberg J (2003) SNARE selectivity of the COPII coat. Cell 114: 483-495
17. Mossessova E, Lima CD (2000) Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast. Mol Cell 5: 865-876
18. Nishimura N, Bannykh S, Slabough S, Matteson J, Altschuler Y, Hahn K, Balch WE (1999) A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum. J Biol Chem 274: 15937-15946
19. Stagg SM, Gürkan C, Fowler DM, LaPointe P, Foss TR, Potter CS, Carragher B, Balch WE (2006) Structure of the Sec13/31 COPII coat cage. Nature 439: 234-238
20. Votsmeier C, Gallwitz D (2001) An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export. EMBO J 20: 6742-6750
21. Wendeler MW, Paccaud JP, Hauri HP (2007) Role of Sec24 isoforms in selective export of membrane proteins from the endoplasmic reticulum. EMBO Rep 8: 258-264