|
Volumn 18, Issue 23, 2008, Pages 6236-6239
|
Modifications of the isonipecotic acid fragment of SNS-032: Analogs with improved permeability and lower efflux ratio
|
Author keywords
CDK; Cyclin; Kinase; SNS 032
|
Indexed keywords
CYCLIN DEPENDENT KINASE 1;
CYCLIN DEPENDENT KINASE 2;
CYCLIN DEPENDENT KINASE 4;
CYCLIN DEPENDENT KINASE 7;
CYCLIN DEPENDENT KINASE 9;
ISONIPECOTIC ACID;
N [5 (5 TERT BUTYL 2 OXAZOLYLMETHYLTHIO) 2 THIAZOLYL]ISONIPECOTAMIDE;
ANIMAL CELL;
ARTICLE;
DRUG PENETRATION;
DRUG STRUCTURE;
DRUG SYNTHESIS;
DRUG TRANSPORT;
ENANTIOMER;
ENZYME INHIBITION;
IC 50;
NONHUMAN;
REACTION ANALYSIS;
STRUCTURE ANALYSIS;
ANIMALS;
COMBINATORIAL CHEMISTRY TECHNIQUES;
CYCLIN-DEPENDENT KINASE 2;
ISONIPECOTIC ACIDS;
MICE;
MOLECULAR STRUCTURE;
OXAZOLES;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
THIAZOLES;
|
EID: 55549135313
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2008.09.099 Document Type: Article |
Times cited : (7)
|
References (15)
|