Effect of GnRH down-regulation on cumulus cell viability and apoptosis as measured by fluorescence-activated cell sorting

Journal of Assisted Reproduction and Genetics

Volumn 25, Issue 9-10, 2008, Pages 467-471

  Hassun Filho, Pericles Assad ^a   Ribeiro, Mariana Antunes ^b   Da Rocha, André Monteiro ^b   Allegreti, José Roberto ^b   Serafini, Paulo Cesar ^b   Da Motta, Eduardo Leme Alves ^b  

^a Genesis Genetics Brazil ^*  (Brazil)

^b Huntington Reproductive Medicine   (Brazil)

Author keywords

Apoptosis; ART; Cumulus cells; Flow cytometry; GnRH; Ovarian stimulation

Indexed keywords

ESTRADIOL; GONADORELIN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST;

ADULT; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL VIABILITY; CLINICAL ARTICLE; DOWN REGULATION; FEMALE; FERTILIZATION IN VITRO; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; IMPLANTATION; OUTCOME ASSESSMENT; PREGNANCY RATE; PRIORITY JOURNAL;

ADULT; APOPTOSIS; CELL SURVIVAL; CUMULUS CELLS; DOWN-REGULATION; EMBRYO IMPLANTATION; FEMALE; FERTILIZATION IN VITRO; FLOW CYTOMETRY; GONADOTROPIN-RELEASING HORMONE; HUMANS; OVULATION INDUCTION;

EID: 55549119926     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10815-008-9263-9     Document Type: Article

References (24)

1. SJ Muasher RT Abdallah ZR Hubayter 2006 Optimal stimulation protocols for in vitro fertilization Fertil Steril. 86 267 73 doi:10.1016/j.fertnstert.2005. 09.067
2. F Giampietro S Sancilio GM Tiboni RA Rana R Di Pietro 2006 Levels of apoptosis in human granulosa cells seem to be comparable after therapy with a gonadotropin-releasing hormone agonist or antagonist Fertil Steril. 85 412 9 doi:10.1016/j.fertnstert.2005.08.020
3. A Palumbo Y Yeh 1995 Apoptosis as a basic mechanism in the ovarian cycle: follicular atresia and luteal regression J Soc Gynecol Investig. 2 565 73 doi:10.1016/1071-5576(94)00062-6
4. JL Tilly KIN Kowalski AL Johnson AD Such 1991 Involvement of apoptosis in ovarian follicles atresia and postovulatory regression Endocrinology. 129 2799 801
5. H Billig I Furuta AJ Hsueh 1994 Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells Endocrinology. 134 245 52 doi:10.1210/en.134.1.245
6. GN Piquette JL Tilly LE Prichard C Simon ML Polan 1994 Detection of apoptosis in human and rat ovarian follicles J Soc Gynecol Investig. 1 297 301
7. T Kaneko H Saito T Takahashi N Ohta T Saito M Hiroi 2000 Effects of controlled ovarian hyperstimulation on oocyte quality in terms of the incidence of apoptotic granulosa cells J Assist Reprod Genet. 17 580 5 doi:10.1023/A:1026439409584
8. Thoma FH, Vanderhyden BC. Oocyte granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth. Reprod Biol Endocrinol. 4:19. ( http://www.rbej.com./content/4/1/ 19 ).
9. K Nakahara H Saito T Saito M Ito N Ohta T Takahashi 1997 The incidence of apoptotic bodies in membrane granulosa can predict prongnosis of ova from patients participating in invitro fertilization programs Fertil Steril. 68 312 7 doi:10.1016/S0015-0282(97)81521-X
10. C Sifer JL Bénifla AF Bringuier R Porcher G Blanc-Layrac P Madélénat 2002 Could induced apoptosis of granulosa cells predict in vitro fertilization-embryo transfer? A preliminary study of 25 women Eur J Obstet Gynecol Reprod Biol. 103 150 3 doi:10.1016/S0301-2115(02)00043-X
11. E Bencomo R Pérez MF Arteaga E Acosta O Pena L Lopez 2006 Apoptosis of cultured granulosa-lutein cells is reduced by insulin-like growth factor I and may correlate with embryo fragmentation and pregnancy rate Fertil Steril. 85 474 80 doi:10.1016/j.fertnstert.2005.08.014
12. CS Suh BC Jee YM Choi JG Kim JY Lee SY Moon 2002 Prognosis implication of apoptosis in human luteinized granulosa cells during IVF-ET J Assist Reprod Genet. 19 209 14 doi:10.1023/A:1015319617598
13. GJ Oosterhuis HW Michgelsen CB Lambalk J Schoemaker I Vermes 1998 Apoptotic cell death in human granulosa lutein cells: a possible indicator of in vitro fertilization outcome Fertil Steril. 70 747 9 doi:10.1016/S0015-0282(98) 00266-0
14. CM Corn C Hauser-Kronberger M Moser G Tews T Ebner 2005 Predictive value of cumulus cell apoptosis with regard to blastocyst development of corresponding gametes Fertil Steril. 84 627 33 doi:10.1016/j.fertnstert.2005.03.061
15. P Serafini I Yadid ELA Motta JR Alegretti J Fioravanti M Coslovsky 2006 Ovarian stimulation with daily late follicular phase administration of low-dose human chorionic gonadotropin for in vitro fertilization: a prospective, randomized trial Fertil Steril. 86 830 8 doi:10.1016/j.fertnstert.2006.02.110
16. G Ruvolo L Bosco A Pane G Morici E Cittadini MC Roccheri 2007 Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures Fertil Steril. 87 542 6 doi:10.1016/j.fertnstert.2006. 06.059
17. Veeck L. Atlas of the human Ooocyte and Early Conceptus, vol 2. Baltimore: Williams & Wilkins; 1991.
18. Zar JH. Biostatistical analysis. New Jersey: Prentice Hall; 1999.
19. AJW Hsueh H Billing A Tsafriri 1994 Ovarian Follicle Atresia: a hormonally controlled apoptotic process Endocr Rev. 15 707 24 doi:10.1210/er.15.6.707
20. A Amsterdam I Keren-Tal D Aharoni 1996 Cross-talk between cAMP and p53-generated signals in induction of differentiation and apoptosis in steroidogenic granulosa cells Steroids. 61 252 6 doi:10.1016/0039-128X(96)00031- 1
21. A Amsterdam A Dantes N Selvaraj D Aharoni 1997 Apoptosis in steroidogenic cells: structure-function analysis Steroids. 62 207 11 doi:10.1016/S0039- 128X(96)00182-1
22. A Amsterdam A Dantes K Hosokawa CP Schere-Levy F Kotsuji D Aharoni 1998 Steroid regulation during apoptosis of ovarian follicular cells Steroids. 63 314 8 doi:10.1016/S0039-128X(98)00016-6
23. A Amsterdam I Keren-Tal D Aharoni A Dantes A Land-Bracha E Rimon 2003 Steroidogenesis and apoptosis in the mammalian ovary Steroids. 68 861 7 doi:10.1016/j.steroids.2003.09.003
24. RC Chian A Ao HJ Clarke T Tulandi SL Tan 1999 Production of steroids from human cumulus cells treated with different concentrations of gonadotropins during culture in vitro Fertil Steril. 71 61 6 doi:10.1016/S0015-0282(98)00416-6