Local and systemic up-regulation of TNFα, IL-1β and IL-6 in mice intratracheally inoculated with Porphyromonas gingivalis

Acta Veterinaria Brno

Volumn 77, Issue 3, 2008, Pages 377-385

  Pavlica, Zlatko ^a,c   Nemec, A ^a   Nemec Svete, A ^a   Erzen D ^b   Crossley, D A ^a   Petelin, M ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY CLINIC OF RESPIRATORY AND ALLERGIC DISEASES   (Slovenia)

^c NONE   (Slovenia)

Author keywords

Mice; Periodontopathogenic bacteria; Proinflammatory cytokines; Systemic effects

Indexed keywords

ANIMALIA; BACTERIA (MICROORGANISMS); MUS; PORPHYROMONAS GINGIVALIS;

EID: 55549105083     PISSN: 00017213     EISSN: None     Source Type: Journal    
DOI: 10.2754/avb200877030377     Document Type: Article

References (33)

1. BAYLIS C 1987: Effects of administered thromboxanes on the intact, normal rat kidney. Ren Physiol 10: 110-121
2. BRADFORD MM 1976: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-54
3. COOK HT, SULLIVAN R 1991: Glomerular nitrite synthesis in in situ immune complex glomerulonephritis in the rat. Am J Pathol 139: 1047-1052
4. DeBOWES LJ, MOSIER D, LOGAN E, HARVEY CE, LOWRY S, RICHARDSON DC 1996: Association of periodontal disease and histologic lesions in multiple organs from 45 dogs. J Vet Dent 13: 57-60
5. EBERSOLE JL, CAPPELLI D, MATHYS EC, STEFFEN MJ, SINGER RE, MONTGOMERY M, MOTT GE, NOVAK MJ 2002: Periodontitis in humans and non-human primates: oral-systemic linkage inducing acute phase proteins. Ann Periodontol 7: 102-111
6. FRANEK E, BLACH A, WITULA A, KOLONKO A, CHUDEK J, DRUGACZ J, WIECEK A 2005: Association between chronic periodontal disease and left ventricular hypertrophy in kidney transplant recipients. transplantation 80: 3-5
7. KARZAI W, CUI X, MEHLHORN B, STRAUBE E, HARTUNG T, GERSTENBERGER E, BANKS SM, NATANSON C, REINHART K, EICHACKER PQ 2003: Protection with antibody to tumor necrosis factor differs with similarly lethal Escherichia coli versus Staphylococcus aureus pneumonia in rats. Anesthesiology 99: 81-89
8. KHLGATIAN M, NASSAR H, CHOU HH, GIBSON FC, 3RD, GENCO CA 2002: Fimbria-dependent activation of cell adhesion molecule expression in Porphyromonas gingivalis-infected endothelial cells. Infect Immun 70: 257-267
9. KIKUCHI, T, KOBAYASHI T, GOMI, K, SUZUKI, T, TOKUE, Y, WATANABE, A, NUKIWA, T 2004: Dendritic cells pulsed with live and dead Legionella pneumophila elicit distinct immune responses. J Immunol 172: 1727 - 1734
10. KIMIZUKA R, KATO T, ISHIHARA K, OKUDA K 2003: Mixed infections with Porphyromonas gingivalis and Treponema denticola cause excessive inflammatory responses in a mouse pneumonia model compared with monoinfections. Microbes Infect 5: 1357-1362
11. LAH TT, BABNIK J, SCHIFFMANN E, TURK V, SKALERIC U 1993: Cysteine proteinases and inhibitors in inflammation: their role in periodontal disease. J Periodontol 64: 485-491
12. LAMONT RJ, JENKINSON HF 1998: Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 62: 1244-1263
13. MACDOUGALL DF, COOK T, STEWARD AP, CATTELL V 1986: Canine chronic renal disease: prevalence and types of glomerulonephritis in the dog. Kidney Int 29: 1144-1151
14. MOLLOY RG, MANNICK JA, RODRICK ML 1993: Cytokines, sepsis and immunomodulation. Br J Surg 80: 289-297
15. NELSON S, BAGBY GJ, BAINTON BG, WILSON LA, THOMPSON JJ, SUMMER WR 1989: Compartmentalization of intraalveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis 159: 189-194
16. NIETO FJ 1998: Infections and atherosclerosis: new clues from an old hypothesis? Am J Epidemiol 148: 937-948
17. ORTIZ A, GOMEZ-CHIARRI M, LERMA JL, GONZALEZ E, EGIDO J 1991: The role of platelet-activating factor (PAF) in experimental glomerular injury. Lipids 26: 1310-1315
18. PASTER BJ, BOCHES SK, GALVIN JL, ERICSOR RE, LAU CN, LEVANOS VA, SAHASRABUDHE A, DEWHIRST FE 2001: Bacterial diversity in human subgingival plaque. J Bacteriol 183: 3770-3783
19. PAVLICA Z, PETELIN M, ŠTIBLAR-MARTINČIČ D, NEMEC A, NEMEC AL, ERŽEN D, SKALERIČ U 2006: Inflammatory and immune responses in mice after peroral infection with Porphyromonas gingivalis. Zobozdrav Vestn 61: 73-82
20. PETELIN M, NARUISHI K, SHIOMI N, MINESHIBA J, ARAI H, NISHIMURA F, TAKASHIBA S, MURAYAMA Y 2004: Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice. Exp Mol Pathol 76: 76-81
21. RENVERT S, WIKSTROM M, MUGRABI M, CLAFFEY n 1996: Histological and microbiological aspects of ligature-induced periodontitis in beagle dogs. J Clin Periodontol 23: 310-319
22. RUSSELL SL, BOYLAN RJ, KASLICK RS, SCANNAPIECO FA, KATZ RV 1999: Respiratory pathogen colonization of the dental plaque of institutionalized elders. Spec Care Dentist 19: 128-134
23. SCANNAPIECO FA 1994: Saliva-bacterium interactions in oral microbial ecology. Crit Rev Oral Biol Med 5: 203-248
24. SCANNAPIECO FA 2005: Systemic effects of periodontal diseases. Dent Clin North Am 49: 533-550
25. SCANNAPIECO FA, GENCO RJ 1999: Association of periodontal infections with atherosclerotic and pulmonary diseases. J Periodontal Res 34: 340-345
26. SEDOR JR, KONIECZKOWSKI M, HUANG S, GRONICH JH, NAKAZATO Y, GORDON G, KING CH 1993: Cytokines, mesangial cell activation and glomerular injury. Kidney Int Suppl 39: S65-S70
27. SHARMA A, NOVAK EK, SOJAR HT, SWANK RT, KURAMITSU HK, GENCO RJ 2000: Porphyromonas gingivalis platelet aggregation activity: outer membrane vesicles are potent activators of murine platelets. Oral Microbiol Immunol 15: 393-396
28. SVANBORG, C, HEDLUND, M, CONNELL, H, AGACE, W, DUAN, R D, NILSSON, A, WULLT, B 1996: Bacterial adherence and mucosal cytokine responses. Receptors and transmembrane signaling. Ann N Y Acad Sci 797: 177-90
29. ULICH TR, WATSON LR, YIN SM, GUO KZ, WANG P, THAGG H, DEL CASTILLO J 1991: The intratracheal administration of endotoxin and cytokines. I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate. Am J Pathol 138: 1485-1496
30. VAN DEN BERG WB 2001: Anti-cytokine therapy in chronic destructive arthritis. Arthritis Res 3: 18-26
31. rd ed. Georg Thieme Verlag, Stuttgart, 38 p.
32. WONG GG, CLARK SC 1988: Multiple actions of interleukin 6 within a cytokine network. Immunol Today 9: 137-139
33. XING Z, GAULDIE J, COX G, BAUMANN H, JORDANA M, LEI XF, ACHONG MK 1998: IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest 101: 311-320