Urocanic acid-modified chitosan-mediated p53 gene delivery inducing apoptosis of human hepatocellular carcinoma cell line HepG2 is involved in its antitumor effect in vitro and in vivo

Biochemical and Biophysical Research Communications

Volumn 377, Issue 2, 2008, Pages 567-572

  Wang, Wei ^a   Yao, Jing ^a   Zhou, Jian Ping ^a   Lu, Yun ^a   Wang, Yu ^a   Tao, Lei ^a   Li, Yi Ping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Hepatocellular carcinoma; P53 gene delivery; Urocanic acid modified chitosan

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; CHITOSAN; ENHANCED GREEN FLUORESCENT PROTEIN; LIPOCORTIN 5; MESSENGER RNA; PROTEIN P53; UROCANIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CELL STRAIN HEPG2; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CHITOSAN; GENE THERAPY; HUMANS; LIVER NEOPLASMS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UROCANIC ACID;

MUS MUSCULUS;

EID: 55549089604     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.023     Document Type: Article

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