Multiple evolutionarily conserved enhancers control expression of Eya1

Developmental Dynamics

Volumn 237, Issue 11, 2008, Pages 3142-3156

  Ishihara, Tadashi ^a   Sato, Shigeru ^a   Ikeda, Keiko ^a   Yajima, Hiroshi ^a   Kawakami, Kiyoshi ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Chick; Electroporation; Enhancer; Evolutionarily conserved elements; Eya1

Indexed keywords

ARTICLE; CHICK EMBRYO; CONTROLLED STUDY; ELECTROPORATION; EMBRYONIC STRUCTURES; EXON; EYA 1 GENE; GENE; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; MOLECULAR EVOLUTION; MORPHOGENESIS; MUTATIONAL ANALYSIS; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BRAIN; CHICK EMBRYO; ENHANCER ELEMENTS, GENETIC; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUTATION; NUCLEAR PROTEINS; ORGAN SPECIFICITY; PROTEIN TYROSINE PHOSPHATASES; QUANTITATIVE TRAIT LOCI; SOMITES; SPECIES SPECIFICITY;

VERTEBRATA;

EID: 55549087607     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.21716     Document Type: Article

References (39)

1. Abdelhak S, Kalatzis V, Heilig R, Compain S, Samson D, Vincent C, Levi-Acobas F, Cruaud C, Le Merrer M, Mathieu M, König R, Vigneron J, Weissenbach J, Petit C, Weil D. 1997a. Clustering of mutations responsible for branchio-oto-renal (BOR) syndrome in the eyes absent homologous region (eyaHR) of EYA1. Hum Mol Genet 6:2247-2255.
2. Abdelhak S, Kalatzis V, Heilig R, Compain S, Samson D, Vincent C, Weil D, Cruaud C, Sahly I, Leibovici M, Bitner-Glindzicz M, Francis M, Lacombe D, Vigneron J, Charachon R, Boven K, Bedbeder P, Van Regemorter N, Weissenbach J, Petit C. 1997b. A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family. Nat Genet 15:157-164.
3. Boffelli D, Nobrega MA, Rubin EM. 2004. Comparative genomics at the vertebrate extremes. Nat Rev Genet 5:456-465.
4. Bonini NM, Leiserson WM, Benzer S. 1993. The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell 72:379-395.
5. Brudno M, Do CB, Cooper GM, Kim MF, Davydov E, Green ED, Sidow A, Batzoglou S. 2003. LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res 13:721-731.
6. Chang EH, Menezes M, Meyer NC, Cucci RA, Vervoort VS, Schwartz CE, Smith RJ. 2004. Branchio-oto-renal syndrome: the mutation spectrum in EYA1 and its phenotypic consequences. Hum Mutat 23:582-589.
7. Chen R, Amoui M, Zhang Z, Mardon G. 1997. Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila. Cell 91:893-903.
8. Cheng Y, Cheung M, Abu-Elmagd MM, Orme A, Scotting PJ. 2000. Chick sox10, a transcription factor expressed in both early neural crest cells and central nervous system. Brain Res Dev Brain Res 121:233-241.
9. Conte I, Bovolenta P. 2007. Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain. Genome Biol 8:R137.
10. de Melker AA, Desban N, Duband JL. 2004. Cellular localization and signaling activity of beta-catenin in migrating neural crest cells. Dev Dyn 230:708-726.
11. Frazer KA, Pachter L, Poliakov A, Rubin EM, Dubchak I. 2004. VISTA: computational tools for comparative genomics. Nucleic Acids Res 32:W273-279.
12. Hamburger V, Hamilton HL. 1951. A series of normal stages in the development of the chick embryo. J Morphol 88:49-92.
13. Hans S, Christison J, Liu D, Westerfield M. 2008. Fgf-dependent otic induction requires competence provided by FoxiI and Dlx3b. BMC Dev Biol 7:5.
14. Inoue M, Kamachi Y, Matsunami H, Imada K, Uchikawa M, Kondoh H. 2007. PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development. Genes Cells 12:1049-1061.
15. Ishihara T, Ikeda K, Sato S, Yajima H, Kawakami K. 2008. Differential expression of Eya1 and Eya2 during chick early embryonic development. Gene Expr Patterns 8:357-367.
16. Kozlowski DJ, Whitfield TT, Hukriede NA, Lam WK, Weinberg ES. 2005. The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line. Dev Biol 277:27-41.
17. Kutejova E, Engist B, Self M, Oliver G, Kirilenko P, Bobola N. 2008. Six2 functions redundantly immediately downstream of Hoxa2. Development 135:1463-1470.
18. Loots GG, Ovcharenko I. 2004. rVISTA 2.0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res 32:W217-221.
19. Matsuda T, Cepko CL. 2004. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc Natl Acad Sci USA 101:16-22.
20. Matsumata M, Uchikawa M, Kamachi Y, Kondoh H. 2005. Multiple N-cadherin enhancers identified by systematic functional screening indicate its Group B1 SOX-dependent regulation in neural and placodal development. Dev Biol 286:601-617.
21. Nica G, Herzog W, Sonntag C, Nowak M, Schwarz H, Zapata AG, Hammerschmidt M. 2006. Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis. Dev Biol 292:189-204.
22. Ohto H, Kamada S, Tago K, Tominaga SI, Ozaki H, Sato S, Kawakami K. 1999. Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. Mol Cell Biol 19:6815-6824.
23. Oosterwegel M, van de Wetering M, Timmerman J, Kruisbeek A, Destree O, Meijlink F, Clevers H. 1993. Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis. Development 118:439-448.
24. Ovcharenko I, Loots GG, Giardine BM, Hou M, Ma J, Hardison RC, Stubbs L, Miller W. 2005. Mulan: multiple-sequence local alignment and visualization for studying function and evolution. Genome Res 15:184-194.
25. Ozaki H, Nakamura K, Funahashi J, Ikeda K, Yamada G, Toakno H, Okamura HO, Kitamura K, Muta S, Kotaki H, Sudo K, Horai R, Iwakura Y, Kawakami K. 2004. Six1 controls pattering of the mouse otic vesicle. Development 131:551-562.
26. Pennacchio LA, Ahituv N, Moses AM, Prabhakar S, Nobrega MA, Shoukry M, Minovitsky S, Dubchak I, Holt A, Lewis KD, Plajzer-Frick I, Akiyama J, De Val S, Afzal V, Black BL, Couronne O, Eisen MB, Visel A, Rubin EM. 2006. In vivo enhancer analysis of human conserved noncoding sequences. Nature 444:499-502.
27. Robb L, Hartley L, Wang CC, Harvey RP, Begley CG. 1998. musculin: a murine basic helix-loop-helix transcription factor gene expressed in embryonic skeletal muscle. Mech Dev 76:197-201.
28. Sanggaard KM, Rendtorff ND, Kjaer KW, Eiberg H, Johnsen T, Gimsing S, Dyrmose J, Nielsen KO, Lage K, Tranebjaerg L. 2007. Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses. Eur J Hum Genet 15:1121-1131.
29. Sato S, Nakamura M, Cho DH, Tapscott SJ, Ozaki H, Kawakami K. 2002. Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1. Hum Mol Genet 11:1045-1058.
30. Schmidt M, Patterson M, Farrell E, Munsterberg A. 2004. Dynamic expression of Lef/Tcf family members and beta-catenin during chick gastrulation, neurulation, and early limb development. Dev Dyn 229:703-707.
31. Schug J. 2003. Unit 2.6: Using TESS to predict transcription factor binding sites in DNA sequence. In: Current protocols in bioinformatics 21:2.6.1-2.6.15. Hoboken, NJ: John Wiley and Sons.
32. Uchikawa M, Ishida Y, Takemoto T, Kamachi Y, Kondoh H. 2003. Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals. Dev Cell 4:509-519.
33. Uchikawa M, Takemoto T, Kamachi Y, Kondoh H. 2004. Efficient identification of regulatory sequences in the chicken genome by a powerful combination of embryo electroporation and genome comparison. Mech Dev 121:1145-1158.
34. Varela-Echavarria A, Pfaff SL, Guthrie S. 1996. Differential expression of LIM homeobox genes among motor neuron subpopulations in the developing chick brain stem. Mol Cell Neurosci 8:242-257.
35. von Scheven G, Bothe I, Ahmed MU, Alvares LE, Dietrich S. 2006. Protein and genomic organisation of vertebrate MyoR and Capsulin genes and their expression during avian development. Gene Expr Patterns 6:383-393.
36. Xu PX, Adams J, Peters H, Brown MC, Heaney S, Maas R. 1999. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet 23:113-117.
37. Xu PX, Woo I, Her H, Beier DR, Maas RL. 1997. Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development 124:219-231.
38. Xu PX, Zheng W, Laclef C, Maire P, Maas RL, Peters H, Xu X. 2002. Eya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroid. Development 129:3033-3044.
39. Zou D, Silvius D, Fritzsch B, Xu PX. 2004. Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. Development 131:5561-5572.