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Volumn 14, Issue 30, 2008, Pages 4735-4738

Therapy for acute pancreatitis with platelet-activating factor receptor antagonists

Author keywords

Acute pancreatitis; BN52021; Lexipafant; Platelet activating factor; Platelet activating factor receptor antagonist

Indexed keywords

3 BROMO 5 [N PHENYL N [2 [[2 (1,2,3,4 TETRAHYDRO 2 ISOQUINOLYLCARBONYLOXY)ETHYL]CARBAMOYL]ETHYL]CARBAMOYL] 1 PROPYLPYRIDINIUM NITRATE; APAFANT; BEPAFANT; GINKGOLIDE B; LEXIPAFANT; PLACEBO; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; ANTIINFLAMMATORY AGENT; ANTITHROMBOCYTIC AGENT; AZEPINE DERIVATIVE; DRUG DERIVATIVE; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GINKGOLIDE; IMIDAZOLE DERIVATIVE; LACTONE; LEUCINE; PYRIDINIUM DERIVATIVE; TETRAHYDROISOQUINOLINE DERIVATIVE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; TRIAZOLE DERIVATIVE;

EID: 55449132205     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.4735     Document Type: Review
Times cited : (26)

References (34)
  • 1
    • 47849092483 scopus 로고    scopus 로고
    • Severe acute pancreatitis in the elderly: Etiology and clinical characteristics
    • Xin MJ, Chen H, Luo B, Sun JB. Severe acute pancreatitis in the elderly: Etiology and clinical characteristics. World J Gastroenterol 2008; 14: 2517-2521
    • (2008) World J Gastroenterol , vol.14 , pp. 2517-2521
    • Xin, M.J.1    Chen, H.2    Luo, B.3    Sun, J.B.4
  • 2
    • 15944393587 scopus 로고    scopus 로고
    • Outcome of severe acute pancreatis
    • Malangoni MA, Martin AS. Outcome of severe acute pancreatis. Am J Surg 2005; 189: 273-277.
    • (2005) Am J Surg , vol.189 , pp. 273-277
    • Malangoni, M.A.1    Martin, A.S.2
  • 4
    • 0032916081 scopus 로고    scopus 로고
    • Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis
    • Johnson CD. Platelet-activating factor and platelet-activating factor antagonists in acute pancreatitis. Dig Surg 1999; 16: 93-101
    • (1999) Dig Surg , vol.16 , pp. 93-101
    • Johnson, C.D.1
  • 5
    • 1542407663 scopus 로고    scopus 로고
    • Platelet activating factor receptor binding plays a critical role in jet fuel-induced immune suppression
    • Ramos G, Kazimi N, Nghiem DX, Walterscheid JP, Ullrich SE. Platelet activating factor receptor binding plays a critical role in jet fuel-induced immune suppression. Toxicol Appl Pharmacol 2004; 195: 331-338
    • (2004) Toxicol Appl Pharmacol , vol.195 , pp. 331-338
    • Ramos, G.1    Kazimi, N.2    Nghiem, D.X.3    Walterscheid, J.P.4    Ullrich, S.E.5
  • 6
    • 33646913594 scopus 로고    scopus 로고
    • Platelet-activating factor (PAF) increase intracellular lipid accumulation by increasing both LDL and scavenger receptors in human mesangial cells
    • Fragopoulou E, Iatrou C, Antonopoulou S, Ruan XZ, Fernando RL, Powis SH, Moorhead JF, Varghese Z. Platelet-activating factor (PAF) increase intracellular lipid accumulation by increasing both LDL and scavenger receptors in human mesangial cells. J Lab Clin Med 2006; 147: 281-289
    • (2006) J Lab Clin Med , vol.147 , pp. 281-289
    • Fragopoulou, E.1    Iatrou, C.2    Antonopoulou, S.3    Ruan, X.Z.4    Fernando, R.L.5    Powis, S.H.6    Moorhead, J.F.7    Varghese, Z.8
  • 7
    • 25444446396 scopus 로고    scopus 로고
    • Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis
    • Zinchuk O, Fukushima A, Zinchuk V, Fukata K, Ueno H. Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis. Mol Vis 2005; 11: 114-123
    • (2005) Mol Vis , vol.11 , pp. 114-123
    • Zinchuk, O.1    Fukushima, A.2    Zinchuk, V.3    Fukata, K.4    Ueno, H.5
  • 9
    • 15944405039 scopus 로고    scopus 로고
    • The role of platelet-activating factor in pathogenesis of type 1 diabetes
    • Ersoy B, Huseyinov A, Darcan S. The role of platelet-activating factor in pathogenesis of type 1 diabetes. Diabetes Care 2005; 28: 980
    • (2005) Diabetes Care , vol.28 , pp. 980
    • Ersoy, B.1    Huseyinov, A.2    Darcan, S.3
  • 11
    • 0033619384 scopus 로고    scopus 로고
    • Nutrition in acute pancreatitis]
    • Zazzo JF. [Nutrition in acute pancreatitis] Schweiz Med Wochenschr 1999; 129: 1617-1625
    • (1999) Schweiz Med Wochenschr , vol.129 , pp. 1617-1625
    • Zazzo, J.F.1
  • 12
    • 0021203265 scopus 로고
    • Acetylcholine-like effects of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine ('platelet-activating factor') and its analogues in exocrine secretory glands
    • Soling HD, Eibl H, Fest W. Acetylcholine-like effects of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine ('platelet-activating factor') and its analogues in exocrine secretory glands. Eur J Biochem 1984; 144: 65-72
    • (1984) Eur J Biochem , vol.144 , pp. 65-72
    • Soling, H.D.1    Eibl, H.2    Fest, W.3
  • 14
    • 0041825238 scopus 로고    scopus 로고
    • Magnitude of effect and special approach to Ginkgo biloba extract EGb 761 in cognitive disorders
    • Le Bars PL. Magnitude of effect and special approach to Ginkgo biloba extract EGb 761 in cognitive disorders. Pharmacopsychiatry 2003; 36 Suppl 1: S44-S49
    • (2003) Pharmacopsychiatry , vol.36 , Issue.SUPPL. 1
    • Le Bars, P.L.1
  • 15
    • 1642492956 scopus 로고    scopus 로고
    • The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis
    • Ewer AK, Al-Salti W, Coney AM, Marshall JM, Ramani P, Booth IW. The role of platelet activating factor in a neonatal piglet model of necrotising enterocolitis. Gut 2004; 53: 207-213
    • (2004) Gut , vol.53 , pp. 207-213
    • Ewer, A.K.1    Al-Salti, W.2    Coney, A.M.3    Marshall, J.M.4    Ramani, P.5    Booth, I.W.6
  • 16
    • 34248222657 scopus 로고    scopus 로고
    • Acute pancreatitis affects non-parenchymal liver cells by a mechanism dependent on platelet-activating factor
    • Souza LJ, Shio MT, Molan NA, Machado MC, Jancar S. Acute pancreatitis affects non-parenchymal liver cells by a mechanism dependent on platelet-activating factor. Pancreatology 2007; 7: 67-73
    • (2007) Pancreatology , vol.7 , pp. 67-73
    • Souza, L.J.1    Shio, M.T.2    Molan, N.A.3    Machado, M.C.4    Jancar, S.5
  • 17
    • 34249802307 scopus 로고    scopus 로고
    • Wang S b, Tang YL, Yang YZ, Xu ZX, Peng K. Opposite effects of WEB2086 on angiogenesis in atheromas and ischemic hindlimb of apoE gene deficient mice. Chin Med J (Engl) 2007; 120: 886-892
    • Wang S b, Tang YL, Yang YZ, Xu ZX, Peng K. Opposite effects of WEB2086 on angiogenesis in atheromas and ischemic hindlimb of apoE gene deficient mice. Chin Med J (Engl) 2007; 120: 886-892
  • 18
    • 0032906182 scopus 로고    scopus 로고
    • Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats
    • Yamaguchi Y, Matsumura F, Liang J, Okabe K, Matsuda T, Ohshiro H, Ishihara K, Akizuki E, Yamada S, Ogawa M. Platelet-activating factor antagonist (TCV-309) attenuates the priming effects of bronchoalveolar macrophages in cerulein-induced pancreatitis rats. Pancreas 1999; 18: 355-363
    • (1999) Pancreas , vol.18 , pp. 355-363
    • Yamaguchi, Y.1    Matsumura, F.2    Liang, J.3    Okabe, K.4    Matsuda, T.5    Ohshiro, H.6    Ishihara, K.7    Akizuki, E.8    Yamada, S.9    Ogawa, M.10
  • 19
    • 1242270580 scopus 로고    scopus 로고
    • Effects of molsidomine and lexipafant in hepatic ischaemia-reperfusion injury
    • Aldemir M, Bosnak M, Al B, Buyukbayram H, Tacyildiz I. Effects of molsidomine and lexipafant in hepatic ischaemia-reperfusion injury. Injury 2004; 35: 232-237
    • (2004) Injury , vol.35 , pp. 232-237
    • Aldemir, M.1    Bosnak, M.2    Al, B.3    Buyukbayram, H.4    Tacyildiz, I.5
  • 20
    • 33747621139 scopus 로고    scopus 로고
    • Effects of lexipafant (BB-882), a platelet activating factor receptor antagonist, on liver damage due to bile duct ligation in rats
    • Ozturk H, Ozturk H, Dokucu AI, Otcu S. Effects of lexipafant (BB-882), a platelet activating factor receptor antagonist, on liver damage due to bile duct ligation in rats. Acta Gastroenterol Belg 2006; 69: 197
    • (2006) Acta Gastroenterol Belg , vol.69 , pp. 197
    • Ozturk, H.1    Ozturk, H.2    Dokucu, A.I.3    Otcu, S.4
  • 21
    • 0032959414 scopus 로고    scopus 로고
    • Treatment with lexipafant ameliorates the severity of pancreatic microvascular endothelial barrier dysfunction in rats with acute hemorrhagic pancreatitis
    • Wang X, Sun Z, Borjesson A, Haraldsen P, Aldman M, Deng X, Leveau P, Andersson R. Treatment with lexipafant ameliorates the severity of pancreatic microvascular endothelial barrier dysfunction in rats with acute hemorrhagic pancreatitis. Int J Pancreatol 1999; 25: 45-52
    • (1999) Int J Pancreatol , vol.25 , pp. 45-52
    • Wang, X.1    Sun, Z.2    Borjesson, A.3    Haraldsen, P.4    Aldman, M.5    Deng, X.6    Leveau, P.7    Andersson, R.8
  • 22
    • 17044378440 scopus 로고    scopus 로고
    • Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant
    • Leveau P, Wang X, Sun Z, Borjesson A, Andersson E, Andersson R. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. Biochem Pharmacol 2005; 69: 1325-1331
    • (2005) Biochem Pharmacol , vol.69 , pp. 1325-1331
    • Leveau, P.1    Wang, X.2    Sun, Z.3    Borjesson, A.4    Andersson, E.5    Andersson, R.6
  • 23
    • 0034900299 scopus 로고    scopus 로고
    • Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis
    • Lane JS, Todd KE, Gloor B, Chandler CF, Kau AW, Ashley SW, Reber HA, McFadden DW. Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis. J Surg Res 2001; 99: 365-370
    • (2001) J Surg Res , vol.99 , pp. 365-370
    • Lane, J.S.1    Todd, K.E.2    Gloor, B.3    Chandler, C.F.4    Kau, A.W.5    Ashley, S.W.6    Reber, H.A.7    McFadden, D.W.8
  • 24
    • 0032994189 scopus 로고    scopus 로고
    • The effect of lexipafant on bacterial translocation in acute necrotizing pancreatitis in rats
    • discussion 617
    • Liu Q, Djuricin G, Rossi H, Bewsey K, Nathan C, Gattuso P, Weinstein RA, Prinz RA. The effect of lexipafant on bacterial translocation in acute necrotizing pancreatitis in rats. Am Surg 1999; 65: 611-616; discussion 617
    • (1999) Am Surg , vol.65 , pp. 611-616
    • Liu, Q.1    Djuricin, G.2    Rossi, H.3    Bewsey, K.4    Nathan, C.5    Gattuso, P.6    Weinstein, R.A.7    Prinz, R.A.8
  • 25
    • 0036342321 scopus 로고    scopus 로고
    • Lexipafant and acute pancreatitis: A critical appraisal of the clinical trials
    • Abu-Zidan FM, Windsor JA. Lexipafant and acute pancreatitis: a critical appraisal of the clinical trials. Eur J Surg 2002; 168: 215-219
    • (2002) Eur J Surg , vol.168 , pp. 215-219
    • Abu-Zidan, F.M.1    Windsor, J.A.2
  • 26
    • 0000918029 scopus 로고    scopus 로고
    • Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis
    • Vincent JL, Spapen H, Bakker J, Webster NR, Curtis L. Phase II multicenter clinical study of the platelet-activating factor receptor antagonist BB-882 in the treatment of sepsis. Crit Care Med 2000; 28: 638-642
    • (2000) Crit Care Med , vol.28 , pp. 638-642
    • Vincent, J.L.1    Spapen, H.2    Bakker, J.3    Webster, N.R.4    Curtis, L.5
  • 27
    • 0035159658 scopus 로고    scopus 로고
    • Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis
    • Johnson CD, Kingsnorth AN, Imrie CW, McMahon MJ, Neoptolemos JP, McKay C, Toh SK, Skaife P, Leeder PC, Wilson P, Larvin M, Curtis LD. Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. Gut 2001; 48: 62-69
    • (2001) Gut , vol.48 , pp. 62-69
    • Johnson, C.D.1    Kingsnorth, A.N.2    Imrie, C.W.3    McMahon, M.J.4    Neoptolemos, J.P.5    McKay, C.6    Toh, S.K.7    Skaife, P.8    Leeder, P.C.9    Wilson, P.10    Larvin, M.11    Curtis, L.D.12
  • 28
    • 0023921543 scopus 로고
    • Immune complex induced pancreatitis: Effect of BN 52021, a selective antagonist of platelet-activating factor
    • Jancar S, De Giaccobi G, Mariano M, Mencia-Huerta JM, Sirois P, Braquet P. Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor. Prostaglandins 1988; 35: 757-770
    • (1988) Prostaglandins , vol.35 , pp. 757-770
    • Jancar, S.1    De Giaccobi, G.2    Mariano, M.3    Mencia-Huerta, J.M.4    Sirois, P.5    Braquet, P.6
  • 29
    • 34447096301 scopus 로고    scopus 로고
    • Significance of platelet activating factor receptor expression in pancreatic tissues of rats with severe acute pancreatitis and effects of BN52021
    • Xia SH, Hu CX, Zhao ZL, Xia GD, Di Y. Significance of platelet activating factor receptor expression in pancreatic tissues of rats with severe acute pancreatitis and effects of BN52021. World J Gastroenterol 2007; 13: 2992-2998
    • (2007) World J Gastroenterol , vol.13 , pp. 2992-2998
    • Xia, S.H.1    Hu, C.X.2    Zhao, Z.L.3    Xia, G.D.4    Di, Y.5
  • 30
    • 2942744532 scopus 로고    scopus 로고
    • Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors
    • Huang SH, Duke RK, Chebib M, Sasaki K, Wada K, Johnston GA. Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1beta2gamma2L GABAA receptors. Eur J Pharmacol 2004; 494: 131-138
    • (2004) Eur J Pharmacol , vol.494 , pp. 131-138
    • Huang, S.H.1    Duke, R.K.2    Chebib, M.3    Sasaki, K.4    Wada, K.5    Johnston, G.A.6
  • 31
    • 0037333821 scopus 로고    scopus 로고
    • Transcriptional suppression of the adrenal cortical peripheral-type benzodiazepine receptor gene and inhibition of steroid synthesis by ginkgolide B
    • Amri H, Drieu K, Papadopoulos V. Transcriptional suppression of the adrenal cortical peripheral-type benzodiazepine receptor gene and inhibition of steroid synthesis by ginkgolide B. Biochem Pharmacol 2003; 65: 717-729
    • (2003) Biochem Pharmacol , vol.65 , pp. 717-729
    • Amri, H.1    Drieu, K.2    Papadopoulos, V.3
  • 32
    • 2442489678 scopus 로고    scopus 로고
    • Beneficial effects of recombinant platelet-activating factor acetylhydrolase and BN 52021 on bacterial translocation in cerulein-induced pancreatitis
    • Bedirli A, Gokahmetoglu S, Sakrak O, Soyuer I, Ince O, Sozuer E. Beneficial effects of recombinant platelet-activating factor acetylhydrolase and BN 52021 on bacterial translocation in cerulein-induced pancreatitis. Eur Surg Res 2004; 36: 136-141
    • (2004) Eur Surg Res , vol.36 , pp. 136-141
    • Bedirli, A.1    Gokahmetoglu, S.2    Sakrak, O.3    Soyuer, I.4    Ince, O.5    Sozuer, E.6
  • 33
    • 0034122493 scopus 로고    scopus 로고
    • Lysosomal activity of pulmonary alveolar macrophages in acute experimental pancreatitis in rats with reference to positive PAF-antagonist (BN 52021) effect
    • Wereszczynska-Siemiatkowska U, Dlugosz JW, Siemiatkowski A, Chyczewski L, Gabryelewicz A. Lysosomal activity of pulmonary alveolar macrophages in acute experimental pancreatitis in rats with reference to positive PAF-antagonist (BN 52021) effect. Exp Toxicol Pathol 2000; 52: 119-125
    • (2000) Exp Toxicol Pathol , vol.52 , pp. 119-125
    • Wereszczynska-Siemiatkowska, U.1    Dlugosz, J.W.2    Siemiatkowski, A.3    Chyczewski, L.4    Gabryelewicz, A.5
  • 34
    • 40749101078 scopus 로고    scopus 로고
    • Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF
    • Grypioti AD, Kostopanagiotou G, Demopoulos CA, Roussos A, Mykoniatis M. Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF. Dig Dis Sci 2008; 53: 1054-1062
    • (2008) Dig Dis Sci , vol.53 , pp. 1054-1062
    • Grypioti, A.D.1    Kostopanagiotou, G.2    Demopoulos, C.A.3    Roussos, A.4    Mykoniatis, M.5


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