Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo

Circulation Research

Volumn 103, Issue 9, 2008, Pages 948-956

  Levay, Agata K ^a   Peacock, Jacqueline D ^a   Lu, Yinhui ^b   Koch, Manuel ^c   Hinton, Robert B ^d   Kadler, Karl E ^b   Lincoln, Joy ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF COLOGNE   (Germany)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Development; Extracellular matrix; Heart valves; Mouse heart development; Transcription factors

Indexed keywords

COLLAGEN FIBER; COLLAGEN TYPE 14; GREEN FLUORESCENT PROTEIN; SCLERAXIS; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; COL14A1 PROTEIN, MOUSE; COLLAGEN; GLYCOPROTEIN; RECOMBINANT PROTEIN; SCX PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARTILAGE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; FEMALE; HEART ATRIOVENTRICULAR NODE; HEART DEVELOPMENT; HEART MUSCLE FIBROSIS; IN VIVO STUDY; MALE; MARKER GENE; MESENCHYME CELL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VALVULAR HEART DISEASE; AGING; ANIMAL; FIBROSIS; GENE EXPRESSION REGULATION; GENETICS; GESTATIONAL AGE; GROWTH, DEVELOPMENT AND AGING; HEART VALVE; MESODERM; METABOLISM; MOUSE MUTANT; ORGANOGENESIS; PRENATAL DEVELOPMENT; ULTRASTRUCTURE;

AGING; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARTILAGE; CELL DIFFERENTIATION; CELL LINEAGE; COLLAGEN; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; GLYCOPROTEINS; GREEN FLUORESCENT PROTEINS; HEART VALVE DISEASES; HEART VALVES; MESODERM; MICE; MICE, KNOCKOUT; ORGANOGENESIS; RECOMBINANT PROTEINS;

EID: 55449128620     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.177238     Document Type: Article

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