Relationship of perioperative hyperglycemia and postoperative infections in patients who undergo general and vascular surgery

Annals of Surgery

Volumn 248, Issue 4, 2008, Pages 585-590

  Rogers, Selwyn O ^a   Ramos, Margarita ^a   Khalpey, Zain ^a   Lipsitz, Stuart ^a   Steinberg, Jill ^a   Panizales, Maria Theresa ^a   Zinner, Michael ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; ORAL ANTIDIABETIC AGENT; STEROID;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD TRANSFUSION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; EMERGENCY SURGERY; FEMALE; GENERAL SURGERY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPERGLYCEMIA; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OPERATION DURATION; PERIOPERATIVE PERIOD; POSTOPERATIVE INFECTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; SURGICAL RISK; VASCULAR SURGERY; BLOOD; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; FOLLOW UP; INCIDENCE; METABOLISM; MIDDLE AGED; POSTOPERATIVE PERIOD; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SEX RATIO; SURGICAL INFECTION; UNITED STATES;

AGE DISTRIBUTION; BLOOD GLUCOSE; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERGLYCEMIA; INCIDENCE; MALE; MASSACHUSETTS; MIDDLE AGED; POSTOPERATIVE PERIOD; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SEX DISTRIBUTION; SURGICAL WOUND INFECTION; VASCULAR SURGICAL PROCEDURES;

EID: 55449125205     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31818990d1     Document Type: Article

References (36)

1. Herwaldt LA, Cullen JJ, Scholz D, et al. A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections. Infect Control Hosp Epidemiol. 2006;27:1291-1298.
2. Ambiru S, Kato A, Kimura F, et al. Poor postoperative blood glucose control increases surgical site infections after surgery for hepato-biliary- pancreatic cancer: a prospective study in a high-volume institute in Japan. J Hosp Infect. 2008;68:230-233.
3. Gale SC, Sicoutris C, Reilly PM, et al. Poor glycemic control is associated with increased mortality in critically ill trauma patients. Am Surg. 2007;73:454-460.
4. Whitcomb BW, Pradhan EK, Pittas AG, et al. Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations. Crit Care Med. 2005;33:2772-2777.
5. Van den Berghe G, Wilmer A, Hermans G, et al. Intensive insulin therapy in the medical ICU. N Engl J Med. 2006;354:449-461.
6. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001;345:1359-1367.
7. DeFrances CJ, Hall MJ. 2005 national hospital discharge survey. Adv Data. 2007:1-19.
8. Noordzij PG, Boersma E, Schreiner F, et al. Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery. Eur J Endocrinol. 2007;156:137-142.
9. Sperry JL, Frankel HL, Vanek SL, et al. Early hyperglycemia predicts multiple organ failure and mortality but not infection. J Trauma. 2007;63:487-493; discussion 493-494.
10. Ganai S, Lee KF, Merrill A, et al. Adverse outcomes of geriatric patients undergoing abdominal surgery who are at high risk for delirium. Arch Surg. 2007;142:1072-1078.
11. Mahid SS, Polk HC Jr, Lewis JN, et al. Opportunities for improved performance in surgical specialty practice. Ann Surg. 2008;247:380-388.
12. Brown JR, Edwards FH, O'Connor GT, et al. The diabetic disadvantage: historical outcomes measures in diabetic patients undergoing cardiac surgery -the pre- intravenous insulin era. Semin Thorac Cardiovasc Surg. 2006;18:281-288.
13. Guvener M, Pasaoglu I, Demircin M, et al. Perioperative hyperglycemia is a strong correlate of postoperative infection in type II diabetic patients after coronary artery bypass grafting. Endocr J. 2002;49:531-537.
14. Schmeltz LR, DeSantis AJ, Thiyagarajan V, et al. Reduction of surgical mortality and morbidity in diabetic patients undergoing cardiac surgery with a combined intravenous and subcutaneous insulin glucose management strategy. Diabetes Care. 2007;30:823-828.
15. Vriesendorp TM, Morelis QJ, Devries JH, et al. Early post-operative glucose levels are an independent risk factor for infection after peripheral vascular surgery. A retrospective study. Eur J Vasc Endovasc Surg. 2004;28:520 -525.
16. Scalea TM, Bochicchio GV, Bochicchio KM, et al. Tight glycemic control in critically injured trauma patients. Ann Surg. 2007;246:605-10; discussion 610-612.
17. Swenne CL, Lindholm C, Borowiec J, et al. Peri-operative glucose control and development of surgical wound infections in patients undergoing coronary artery bypass graft. J Hosp Infect. 2005;61:201-212.
18. Khuri SF, Daley J, Henderson W, et al. The department of Veterans affairs' NSQIP: the first national, validated, outcome-based, risk-adjusted, and peer-controlled program for the measurement and enhancement of the quality of surgical care. National VA surgical quality improvement program. Ann Surg. 1998;228:491-507.
19. Khuri SF, Daley J, Henderson W, et al. Risk adjustment of the postoperative mortality rate for the comparative assessment of the quality of surgical care: results of the national Veterans affairs surgical risk study. J Am Coll Surg. 1997;185:315-327.
20. Daley J, Khuri SF, Henderson W, et al. Risk adjustment of the postoperative morbidity rate for the comparative assessment of the quality of surgical care: results of the national Veterans affairs surgical risk study. J Am Coll Surg. 1997;185:328 -340.
21. Khuri SF, Henderson WG, Daley J, et al. The patient safety in surgery study: background, study design, and patient populations. J Am Coll Surg. 2007;204:1089 -1102.
22. Henderson WG, Khuri SF, Mosca C, et al. Comparison of risk-adjusted 30-day postoperative mortality and morbidity in department of Veterans affairs hospitals and selected university medical centers: general surgical operations in men. J Am Coll Surg. 2007;204:1103-1114.
23. Fink AS, Hutter MM, Campbell DC Jr, et al. Comparison of risk-adjusted 30-day postoperative mortality and morbidity in department of Veterans affairs hospitals and selected university medical centers: general surgical operations in women. J Am Coll Surg. 2007;204:1127-1136.
24. Fink AS, Campbell DA Jr, Mentzer RM Jr, et al. The National Surgical Quality Improvement Program in non-veterans administration hospitals: initial demonstration of feasibility. Ann Surg. 2002;236:344-353; discussion 353-354.
25. Daley J, Forbes MG, Young GJ, et al. Validating risk-adjusted surgical outcomes: site visit assessment of process and structure. National VA surgical risk study. J Am Coll Surg. 1997;185:341-351.
26. Bilotta F, Spinelli A, Giovannini F, et al. The effect of intensive insulin therapy on infection rate, vasospasm, neurologic outcome, and mortality in neurointensive care unit after intracranial aneurysm clipping in patients with acute subarachnoid hemorrhage: a randomized prospective pilot trial. J Neurosurg Anesthesiol. 2007;19:156 -160.
27. Lazar HL, Chipkin SR, Fitzgerald CA, et al. Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events. Circulation. 2004; 109:1497-1502.
28. Zerr KJ, Furnary AP, Grunkemeier GL, et al. Glucose control lowers the risk of wound infection in diabetics after open heart operations. Ann Thorac Surg. 1997;63:356-361.
29. Furnary AP, Zerr KJ, Grunkemeier GL, et al. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg. 1999;67:352-360; discussion 360-362.
30. Braithwaite SS, Edkins R, Macgregor KL, et al. Performance of a dose-defining insulin infusion protocol among trauma service intensive care unit admissions. Diabetes Technol Ther. 2006;8:476 -488.
31. Goldberg PA, Sakharova OV, Barrett PW, et al. Improving glycemic control in the cardiothoracic intensive care unit: clinical experience in two hospital settings. JCardiothorac Vasc Anesth. 2004;18:690-697.
32. Lonergan T, Compte AL, Willacy M, et al. A pilot study of the SPRINT protocol for tight glycemic control in critically ill patients. Diabetes Technol Ther. 2006;8:449-462.
33. Taylor BE, Schallom ME, Sona CS, et al. Efficacy and safety of an insulin infusion protocol in a surgical ICU. J Am Coll Surg. 2006;202:1-9.
34. Zimmerman CR, Mlynarek ME, Jordan JA, et al. An insulin infusion protocol in critically ill cardiothoracic surgery patients. Ann Pharmaco- ther. 2004;38:1123-1129.
35. Vriesendorp TM, DeVries JH, Hulscher JB, et al. Early postoperative hyperglycaemia is not a risk factor for infectious complications and prolonged in-hospital stay in patients undergoing oesophagectomy: a retrospective analysis of a prospective trial. Crit Care. 2004;8:R437- R442.
36. Van den Berghe G. First do no harm. hypoglycemia or hyperglycemia? Crit Care Med. 2006;34:2843-2844.