The cerebellar mutism syndrome and its relation to cerebellar cognitive function and the cerebellar cognitive affective disorder

Developmental Disabilities Research Reviews

Volumn 14, Issue 3, 2008, Pages 221-228

  Wells, Elizabeth M ^a   Walsh, Karin S ^a   Khademian, Zarir P ^a   Keating, Robert F ^a   Packer, Roger J ^a,b  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Cerebellar cognitive affective syndrome; Cerebellar mutism; Cerebellum; Medulloblastoma; Posterior fossa

Indexed keywords

METHOTREXATE;

ASTROCYTOMA; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CEREBELLAR MUTISM SYNDROME; CEREBELLUM VERMIS; CLINICAL FEATURE; COGNITION; EPENDYMOMA; HUMAN; MEDULLOBLASTOMA; MOOD DISORDER; MORBIDITY; MUTISM; NEUROIMAGING; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; POSTERIOR CRANIAL FOSSA TUMOR; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SPEECH DISORDER; TREATMENT OUTCOME;

EID: 55449121580     PISSN: 19405510     EISSN: 10982779     Source Type: Journal    
DOI: 10.1002/ddrr.25     Document Type: Review

References (66)

1. Akil H, Statham PF, Götz M, et al. 2006. Adult cerebellar mutism and cognitive-affective syndrome caused by cystic hemangioblastoma. Acta Neurochir 148:597-598.
2. Al-Anazi A, Hassounah M, Sheikh B, et al. 2001. Cerebellar mutism caused by arteriovenous malformation of the vermis. Br J Neurosurg 15:47-50.
3. Andreasen NC, O'Leary DS, Cizadlo T, et al. 1995. PET studies of memory: novel versus practiced free recall of word lists. Neuroimage 2:296-305.
4. Aarsen F, VanDongen H, Paquier P, VanMourik M, Catsman-Berrevoets C. 1995. Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 37:885-893.
5. Aarsen F, VanDongen H, Paquier P, VanMourik M, Catsman-Berrevoets C. 2004. Long-term sequelae in children after cerebellar astrocytoma surgery. Neurology 27:1311-1316.
6. Bellebaum C, Daum I. 2007. Cerebellar involvement in executive control. Cerebellum 6:184-192.
7. Chang YC, Huang CC, Huang SC. 1998. Volumetric neuroimaging in children with neurodevelopmental disorders - mapping the brain and behavior. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 39:285-292.
8. Cornish K, Kogan C, Turk J, Manly T, James N, Mills A, Dalton A. 2005. The emerging fragile X permutation phenotype: evidence from the domain of social cognition. Brain Cogn 57:53-60.
9. Dailey AT, McKhann GM II, Berger MS. 1995. The pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in children. J Neurosurg 83:467-475.
10. De Smet HJ, Baillieux H, Catsman-Berrevoets C, et al. 2007. Postoperative motor speech production in children with the syndrome of 'cerebellar' mutism and subsequent dysarthria: a critical review of the literature. Eur J Paediatr Neurol 11:193-207.
11. Di Cataldo A, Dollo C, Astuto M, et al. 2001. Mutism after surgical removal of a cerebellar tumor: two case reports. Pediatr Hematol Oncol 18:117-121.
12. Dietze DD Jr, Mickle JP. 1990. Cerebellar mutism after posterior fossa surgery. Pediatr Neurosurg 16:25-31.
13. Eckert MA, Leonard CM, Richards TL, et al. 2003. Anatomical correlates of dyslexia: frontal and cerebellar findings. Brain 126 (Part 2):482-494.
14. Ersahin Y, Mutluer S, Caǧli S, et al. 1996. Cerebellar mutism: report of seven cases and review of the literature. Neurosurgery 38:60-65.
15. Erşahin Y, Yararbas U, Duman Y, et al. 2002. Single photon emission tomography following posterior fossa surgery in patients with and without mutism. Childs Nerv Syst 18:318-325.
16. Fujisawa H, Yonaha H, Okumoto K, et al. 2005. Mutism after evacuation of acute subdural hematoma of the posterior fossa. Childs Nerv Syst 21:234-236.
17. Gelabert-González M, Fernández-Villa J. 2001. Mutism after posterior fossa surgery. Review of the literature. Clin Neurol Neurosurg 103:111-114.
18. Giedd JN, Blumenthal J, Molloy E, et al. 2001. Brain imaging of attention deficit/hyperactivity disorder. Ann N Y Acad Sci 931:33-49.
19. Glauser TA, Packer RJ. 1991. Cognitive deficits in long-term survivors of childhood brain tumors. Childs Nerv Syst 7:2-12.
20. Grill J, Viguier D, Kieffer V, et al. 2004. Critical risk factors for intellectual impairment in children with posterior fossa tumors: the role of cerebellar damage. J Neurosurg 101(2 Suppl):152-158.
21. Huber JF, Bradley K, Spiegler BJ, et al. 2006. Long-term effects of transient cerebellar mutism after cerebellar astrocytoma or medulloblastoma tumor resection in childhood. Childs Nerv Syst 22:132-138.
22. Ildan F, Tuna M, Erman T, et al. 2002. The evaluation and comparison of cerebellar mutism in children and adults after posterior fossa surgery: report of two adult cases and review of the literature. Acta Neurochir 144:463-473.
23. Koh S, Turkel SB, Baram TZ. 1997. Cerebellar mutism in children: report of six cases and potential mechanisms. Pediatr Neurol 16:218-219.
24. Leiner HC, Leiner AL, Dow RS. 1986. Does the cerebellum contribute to mental skills? Behav Neurosci 100:443-454.
25. Levisohn L, Cronin-Golomb A, Schmahmann JD. 2000. Neuropsychological consequences of cerebellar tumour resection in children: cerebellar cognitive affective syndrome in a paediatric population. Brain 123:1041-1050.
26. Liu GT, Phillips PC, Molloy PT, et al. 1998. Visual impairment associated with mutism after posterior fossa surgery in children. Neurosurgery 42:253-256.
27. Mabbott DJ, Penkman L, Witol A. 2008. Core neurocognitive functions in children treated for posterior fossa tumors. Neuropsychology 22:159-168.
28. Middleton FA, Strick PL. 1994. Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function. Science 266:458-461.
29. Mostofsky SH, Reiss AL, Lockhart P, et al. 1998. Evaluation of cerebellar size in attention-deficit hyperactivity disorder. J Child Neurol 13:434-439.
30. Mulhern R, Palmer S, Reddick W, Glass J, Kun L, Taylor J, et al. 2001. Risks of young age for selected neurocognitive deficits in medulloblastoma are associated with white matter loss. J Clin Onc 19:472-479.
31. Nandagopal R, Krishnamoorthy SG. 2004. Transient mutism due to posterior circulation infarction. Neurol India 52:510-511.
32. Nicolson R, Fawcett AJ, Dean P. 2001. Dyslexia, development and the cerebellum. Trends Neurosci 24:515-516.
33. Ozgur BM, Berberian J, Aryan HE. 2006. The pathophysiologic mechanism of cerebellar mutism. Surg Neurol 66:18-25.
34. Ozimek A, Richter S, Hein-Kropp C, et al. 2004. Cerebellar mutism - report of four cases. J Neurol 251:963-972.
35. Packer RJ, MacDonald T, Vezina G. 2008. Central nervous system tumors. Pediatr Clin North Am 55:121-145.
36. Packer RJ, Sutton LN, Atkins TE, et al. 1989. A prospective study of cognitive function in children receiving whole-brain radiotherapy and chemotherapy: 2-year results. J Neurosurg 70:707-713.
37. Palmer SL, Reddick WE, Gajjar A. 2007. Understanding the cognitive impact on children who are treated for medulloblastoma. J Pediatr Psychol 32:1040-1049.
38. Papavasiliou AS, Kotsalis C, Trakadas S. 2004. Transient cerebellar mutism in the course of acute cerebellitis. Pediatr Neurol 30:71-74.
39. Petersen SE, Fox PT, Posner MI. 1988. Positron emission tomographic studies of the cortical anatomy of single-word processing. Nature 331:585-589.
40. Pinter JD, Eliez S, Schmitt JE, et al. 2001. Neuroanatomy of Down's syndrome: a high-resolution MRI study. Am J Psychiatry 158:1659-1665.
41. Pollack IF. 1997. Posterior fossa syndrome. Int Rev Neurobiol 41:411-432.
42. Pollack IF, Polinko P, Albright AL, et al. 1995. Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 37:885-893.
43. Riva D, Giorgi C. 2000. The cerebellum contributes to higher functions during development: evidence from a series of children surgically treated for posterior fossa tumours. Brain 123:1051-1061.
44. Robertson PL, Muraszko KM, Holmes EJ, et al. 2006. Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology Group. J Neurosurg 105:444-451.
45. Rønning C, Sundet K, Duc-Tønnessen B, Lundar T, Halseth E. 2005. Persistent cognitive dysfunction secondary to cerebellar injury in patients treated for posterior fossa tumors in childhood. Pediatr Neurosurg 41:15-21.
46. Sadeh M, Cohen I. 2001. Transient loss of speech after removal of posterior fossa tumors - one aspect of a larger neuropsychological entity: the cerebellar cognitive affective syndrome. Pediatr Hematol Oncol 18:423-426.
47. Sagiuchi T, Ishii K, Aoki Y. 2001. Bilateral crossed cerebello-cerebral diaschisis and mutism after surgery for cerebellar medulloblastoma. Ann Nucl Med 15:157-160.
48. Schmahmann JD. 1991. An emerging concept. The cerebellar contribution to higher function. Arch Neurol 48:1178-1187.
49. Schmahmann JD, Sherman JC. 1998. The cerebellar cognitive affective syndrome. Brain 121(Part 4):561-579.
50. Siffert J, Poussaint TY, Goumnerova LC, et al. 2000. Neurological dysfunction associated with postoperative cerebellar mutism. J Neurooncol 48:75-81.
51. Steinbok P, Cochrane DD, Perrin R. 2003. Mutism after posterior fossa tumour resection in children: incomplete recovery on long-term follow-up. Pediatr Neurosurg 39:179-183.
52. Steinlin M. 2007. The cerebellum in cognitive processes: supporting studies in children. Cerebellum 6:237-241.
53. Stoodley CJ, Fawcett AJ, Nicolson RI, et al. 2006. Balancing and pointing tasks in dyslexic and control adults. Dyslexia 12:276-288.
54. Tavano A, Grasso R, Gagliardi C. 2007. Disorders of cognitive and affective development in cerebellar malformations. Brain 130(Part 10):2646-2660.
55. Timmann D, Daum I. 2007. Cerebellar contributions to cognitive functions: a progress report after two decades of research. Cerebellum 6:159-162.
56. Tohgi H, Takahashi S, Chiba K, et al. 1993. Cerebellar infarction. Clinical and neuroimaging analysis in 293 patients. The Tohoku Cerebellar Infarction Study Group. Stroke 24:1697-1701.
57. Turgut M. 1998. Transient "cerebellar" mutism. Childs Nerv Syst 14:161-166.
58. Turgut M. 2007. Re: the pathophysiologic mechanism of cerebellar mutism. Surg Neurol 68:117.
59. Turgut M. 2008. Cerebellar mutism. J Neurosurg Pediatrics 1:262.
60. Urban PP, Marx J, Hunsche S, et al. 2003. Cerebellar speech representation: lesion topography in dysarthria as derived from cerebellar ischemia and functional magnetic resonance imaging. Arch Neurol 60:965-972.
61. Vadeinse D, Hornyak JE. 1997. Linguistic and cognitive deficits associated with cerebellar mutism. Pediatr Rehabil 1:41-44.
62. Van Calenbergh F, Van de Laar A, Plets C, et al. 1995. Transient cerebellar mutism after posterior fossa surgery in children. Neurosurgery 37:894-898.
63. Van Dongen HR, Catsman-Berrevoets CE, van Mourik M. 1994. The syndrome of 'cerebellar' mutism and subsequent dysarthria. Neurology 44:2040-2046.
64. Van Mourik M, Catsman-Berrevoets CE, van Dongen HR, et al. 1997. Complex orofacial movements and the disappearance of cerebellar mutism: report of five cases. Dev Med Child Neurol 39:686-690.
65. Wells EM, Khademian ZP, Walsh KS, et al. Neuroradiographic features of patients with the Cerebellar Mutism Syndrome. Ann Neurol (in press).
66. Zang YF, He Y, Zhu CZ, et al. 2007. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev 29:83-91.