Effect of Bacopa monniera Linn. extract on murine immune response in vitro

Phytotherapy Research

Volumn 22, Issue 10, 2008, Pages 1330-1335

  Saraphanchotiwitthaya, Aurasorn ^a   Ingkaninan, Kornkanok ^a   Sripalakit, Pattana ^a  

^a NARESUAN UNIVERSITY   (Thailand)

Author keywords

Bacopa monniera Linn.; ICR mice; Immunomodulating activity; Lysosomal enzyme activity assay; NBT dye reduction assay; Proliferation assay

Indexed keywords

BACOPA MONNIERI EXTRACT; BACOSIDE A; CONCANAVALIN A; LIPOPOLYSACCHARIDE; PHYTOHEMAGGLUTININ; PLANT EXTRACT; POKEWEED MITOGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACOPA MONNIERI; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; MOUSE; NONHUMAN; PHAGOCYTOSIS; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; BACOPA; CELL PROLIFERATION; FEMALE; HUMANS; IMMUNE SYSTEM; MICE; MICE, INBRED ICR; PLANT EXTRACTS;

BACOPA MONNIERI; MURINAE; MUS; PHYTOLACCACEAE;

EID: 55449112542     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2491     Document Type: Article

References (30)

1. Amirghofran Z, Azadbakht M, Karimi M. 2000. Evaluation of the immunomodulatory effects of five herbal plants. J Ethnopharmacol 72: 167-172.
2. Anbarasi K, Vani G, Balakrishna K, Devi CS. 2005. Effect of bacoside A on membrane-bound ATPases in the brain of rats exposed to cigarette smoke. J Biochem Mol Toxicol 19: 59-65.
3. Bhattacharya SK, Ghosal S. 1998. Anxiolytic activity of a standardized extract of Bacopa monniera: an experimental study. Phytomedicine 5: 77-82.
4. Boonyaprapath N. 1999. Folklore Medicinal Plants (3). Prachachon Company Ltd: Bangkok, 249-250.
5. Channa S, Dar A, Yaqoob M, Anjum S, Sultani Z, Rahman A. 2003. Broncho-vasodilatory activity of fractions and pure constituents isolated from Bacopa monniera. J Ethnopharmacol 86: 27-35.
6. Das A, Shanker G, Nath C, Pal R, Singh S, Singh HK. 2002. A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba: Anticholinesterase and cognitive enhancing activities. Pharmacol Biochem Behav 73: 893-900.
7. Deepak M, Sangli GK, Arun PC, Amit A. 2005. Quantitative determination of the major saponin mixture bacoside A in Bacopa monniera by HPLC. Phytochem Anal 16: 24-29.
8. Dorababu M, Prabha T, Priyambada S, Agrawal VK, Aryya NC, Goel RK. 2004. Effect of Bacopa monniera and Azadirachta indica on gastric ulceration and healing in experimental NIDDM rats. Indian J Exp Biol 42: 389-397.
9. Elangovan V, Govindasamy S, Ramamoorthy N, Balasubramanian K. 1995. In vitro studies on the anticancer activity of Bacopa monnieri. Fitoterapia 66: 211-215.
10. Hirano T, Oka K, Kawashima E, Akiba M. 1989. Effects of synthetic and natural occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytes. Life Sci 45: 1407-1411.
11. Jain P, Khanna NK, Trehan T, Pendse VK, Godhwani JL. 1994. Anti-inflammatory effects of an Ayurvedic preparation, Brahmi Rasayan, in rodents. Indian J Exp Biol 32: 633-636.
12. Kang N-S, Park S-Y, Lee K-R et al. 2002. Modulation of macrophage function activity by ethanolic extract of larvae of Holotrichia diomphalia. J Ethnopharmacol 79: 89-94.
13. Mahato SB, Garai S, Chakravarthy AK. 2000. Bacosaponins E&F: two jujubogenin bisdesmosides from Bacopa monniera. Phytochemistry 53: 711-716.
14. Manosroi A, Saraphanchotiwitthaya A, Manosroi J. 2003. Immunomodulatory activities of Clausena excavata Burm. f. wood extracts. J Ethnopharmacol 89: 155-160.
15. Mookerjee BK, Lee TP, Logue GP, Lippe HA, Middleton E. 1986. Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological and Structural-Activity Relationships. Alan R. Liss.: New York, 511-550.
16. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
17. Nakamura A, Nagai K, Suzuki S, Ando K, Tamura G. 1986. A novel method of screening for immunomodulating substances, establishment of an assay system and its application to culture broths of microorganisms. J Antibiotic 39: 1148-1154.
18. Namgoong SY, Son KH, Chang HW, Kang SS, Kim HP. 1993. Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture. Life Sci 54: 313-320.
19. Pawar R, Gopalakrishnan C, Bhutani KK. 2001. Dammarane triterpene saponin from Bacopa monniera as the superoxide inhibitor in polymorphonuclear cells. Planta Med 67: 752-754.
20. Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK. 2003. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacol Biochem Behav 75: 823-830.
21. Rainard P. 1986. A colorimetric microassay for opsonins by reduction of NBT in phagocytosing bovine polymorphs. J Immunol Methods 90: 197-201.
22. Sairam K, Dorababu M, Goel RK, Bhattacharya SK. 2002. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Phytomedicine 9: 207-211.
23. Singh HK, Dhawan BN. 1997. Neuropsychopharmacological effects of the Ayurvedic nootropic Bacopa monniera Linn (Brahmi). Indian J Pharmacol 29: S359-S365.
24. Sumathi T, Nayeem M, Balakrishna K, Veluchamy G, Devaraj SN. 2002. Alcoholic extract of Bacopa monniera reduces the in vitro effects of morphine withdrawal in guinea-pig ileum. J Ethnopharmacol 82: 75-81.
25. Suzuki I, Tanaka H, Adachi Y, Yadomae T. 1988. Rapid measurement of phagocytosis by macrophages. Chem Pharm Bull 36: 4871-4875.
26. Suzuki I, Tanaka H, Kinoshita A, Oikawa S, Osawa M, Yadomae T. 1990. Effect of orally administered betaglucan on macrophages function in mice. Int J Immunopharmacol 12: 675-684.
27. Swamy SMK, Tan BKH. 2000. Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seed. J Ethnopharmacol 70: 1-7.
28. Vohora SB, Khanna T, Athar M. 1997. Analgesic activity of bacosine, a new triterpene isolated from Bacopa monniera. Fitoterapia 68: 361-365.
29. Vohora D, Pal SN, Pillai KK. 2000. Protection from phenytoin-induced cognitive deficit by Bacopa monniera, a reputed nootropic plant. J Ethnopharmacol 71: 383-390.
30. You K, Son K, Chang H, Kang S, Kim H. 1998. Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro. Planta Med 64: 546-550.