Immunomodulatory activities of Clausena excavata Burm. f. wood extracts

Journal of Ethnopharmacology

Volumn 89, Issue 1, 2003, Pages 155-160

  Manosroi, A ^a   Saraphanchotiwitthaya, A ^b   Manosroi, J ^a  

^a CHIANG MAI UNIVERSITY   (Thailand)

^b NONE

Author keywords

Acetone extract; Aqueous extract; Clausena excavata; Macrophage phagocytosis; Splenocyte proliferation; Thai folklore extract

Indexed keywords

CLAUSENA EXCAVATA EXTRACT; LIPOPOLYSACCHARIDE; LYSOSOME ENZYME; MITOGENIC AGENT; PLANT EXTRACT; POKEWEED MITOGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BIOASSAY; CELL PROLIFERATION; CLAUSENA EXCAVATA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; IMMUNE SYSTEM; IMMUNOMODULATION; IMMUNOPHARMACOLOGY; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; PHAGOCYTOSIS; RESPIRATORY BURST; SPLEEN CELL; T LYMPHOCYTE;

CLAUSENA EXCAVATA;

EID: 0141569088     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(03)00278-2     Document Type: Article

References (19)

1. Chihiro I., Hideki O., Hugh T.W., Hiroshi F. Constituents of Clausena excavata: isolation and structural elucidation of seven new carbazole alkaloids and new coumarin. Chemical and Pharmaceutical Bulletin. 44:1996;2231-2235.
2. Chihiro I., Masataka I., Shinya K., Mitsuo O., Harukuni T., Hoyoku N., Hirichi F. Chemical constituents of Clausena excavata: isolation and structure elucidation of novel furanone-coumarins with inhibitory effects for tumor-promotion. Journal of Natural Products. 63:2000;1218-1224.
3. Huang S.C., Wu P.L., Wu T.S. Two coumarins from the root bark of Clausena excavata. Phytochemistry. 44:1997;179-181.
4. Kang N.-S., Park S.-Y., Lee K.-R., Lee S.-M., Lee B.-G., Shin D.-H., Pyo S. Modulation of macrophage function activity by ethanolic extract of larvae of Holotrichia diomphalia. Journal of Ethnopharmacology. 79:2002;89-94.
5. Mossmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods. 65:1983;55-63.
6. Nakamura A., Nagai K., Suzuki S., Ando K., Tamura G. A novel method of screening for immunomodulating substances, establishment of an assay system and its application to culture broths of microorganisms. Journal of Antibiotics. 39:1986;1148-1154.
7. Puatanachokchai, R., Manosroi, J., Manosroi, A., Aritajat, S., Vinitketkumnuen, U., 1998. Antimutagenicity and anticarcinogenic enzyme inducing activity of San-Soke (Clausena excavata) and Nom-Nang (Pouteria cambodiana). In: Proceedings of the Third International Conference on Environmental Mutagen in Human Population, Bangkok, Thailand, November 29-December 4.
8. Rainard P. A colorimetric microassay for opsonins by reduction of NBT in phagocytosing bovine polymorphs. Journal of Immunological Methods. 90:1986;197-201.
9. Rudi, P.L., 1993. Immunomodulatory compounds. In: Steven, M., Russel, J.M. (Eds.), Bioactive Natural Products: Detection, Isolation, and Structure Determination. CRC Press, London, pp. 279-317.
10. Suzuki I., Tanaka H., Adachi Y., Yadomae T. Rapid measurement of phagocytosis by macrophages. Chemical and Pharmaceutical Bulletin. 36:1988;4871-4875.
11. Suzuki I., Tanaka H., Kinoshita A., Oikawa S., Osawa M., Yadomae T. Effect of orally administered betaglucan on macrophages function in mice. International Journal of Immunopharmacology. 12:1990;675-684.
12. Swarbrick, J.T., 1997. Environmental weeds and exotic plants on Christmas Island, Indian Ocean: a report to Park Australia, 29-30.
13. 8 T lymphocytes levels in advanced cancer patients. In: Proceedings of the 16th Annual Symposium of Health Science, Chiang Mai University, Chiang Mai, Thailand, August 20.
14. Wu T.S., Furukawa H. Biological and phytochemical investigation of Clausena excavata. Journal of Natural Products. 45:1982;718-720.
15. Wu C.C., Ko F.N., Wu T.S., Teng C.M. Antiplatelet effects of clausine-D isolated from Clausena excavata. Biochimica et Biophysica Acta. 1201:1994;1-6.
16. Wu T.S., Huang S.C., Wu P.L. Carbazole alkaloids from stem bark of Clausena excavata. Phytochemistry. 43:1996a;1427-1429.
17. Wu T.S., Huang S.C., Wu P.L. Carbazole-pyranocoumarin dimer and binary carbazole alkaloids from Clausena excavata. Tetrahedron Letters. 37:1996;7819-7822.
18. Wu T.S., Huang S.C., Wu P.L., Teng C.M. Carbazole alkaloids from Clausena excavata and their biological activity. Phytochemistry. 43:1996;133-140.
19. Wu T.S., Huang S.C., Wu P.L., Kuoh C.S. Alkaloidal and other constituents from the root bark of Clausena excavata. Phytochemistry. 52:1999;523-527.