Zinc as a translation regulator in neurons: Implications for P-body aggregation

Journal of Cell Science

Volumn 121, Issue 19, 2008, Pages 3253-3260

  Blumenthal, Jacob ^a   Ginzburg, Irith ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Dcp1a; HuD; Neurons; P bodies; Translation

Indexed keywords

DROSOPHILA PROTEIN; MESSENGER RNA; PROTEIN DCP1A PROTEIN; RNA BINDING PROTEIN; RNA BINDING PROTEIN HUD; RNA BINDING PROTEIN IMP1; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL DISRUPTION; CELL GROWTH; CELL INCLUSION; CELL STIMULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROCESSING BODY; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SUCROSE GRADIENT; SYNAPSE VESICLE; TRANSLATION REGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CYTOPLASMIC STRUCTURES; ENDORIBONUCLEASES; GROWTH CONES; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; HUMANS; NEURONS; PC12 CELLS; POLYRIBOSOMES; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; RATS; RNA; RNA-BINDING PROTEINS; TRANS-ACTIVATORS; ZINC;

EID: 55449100564     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.033266     Document Type: Article

References (29)

1. Alirezaei, M., Nairn, A. C., Glowinski, J., Premont, J. and Marin, P. (1999). Zinc inhibits protein synthesis in neurons: potential role of phosphorylation of translation initiation factor-2alpha. J. Biol. Chem. 274, 32433-32438.
2. An, W. L., Bjorkdahl, C., Liu, R., Cowburn, R. F., Winblad, B. and Pei, J. J. (2005). Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells. J. Neurochem. 92, 1104-1115.
3. Aranda-Abreu, G. E., Behar, L., Chung, S., Furneaux, H. and Ginzburg, I. (1999). Embryonic lethal abnormal vision-like RNA binding proteins regulate neurite outgrowth and tau expression in PC12 Cells. J. Neurosci. 19, 6907-6917.
4. Aronov, S., Marx, R. and Ginzburg, I. (1999). Identification of 3′UTR region implicated in tau mRNA stabilization in neuronal cells. J. Mol. Neurosci. 12, 131-145.
5. Aronov, S., Aranda, G., Behar, L. and Ginzburg, I. (2001). Axonal tau mRNA localization coincides with tau protein in living neuronal cells and depends on axonal targeting signal. J. Neurosci. 21, 6577-6587.
6. Aronov, S., Aranda, G., Behar, L. and Ginzburg, I. (2002). Visualization of translated tau protein in the axons of neuronal P19 cells and characterization of tau RNP granules. J. Cell Sci. 115, 3817-3827.
7. Atlas, R., Behar, L., Elliott, E. and Ginzburg, I. (2004). The insulin-like growth factor mRNA binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells. J. Neurochem. 89, 613-626.
8. Atlas, R., Behar, L., Sapoznik, S. and Ginzburg, I. (2007). Dynamic association with polysomes during P19 neuronal differentiation and an untranslated-region-dependent translation regulation of the tau mRNA by the tau mRNA-associated proteins IMP1, HuD, and G3BP1. J. Neurosci. Res. 85, 173-183.
9. Barbee, S. A., Estes, P. S., Cziko, A. M., Hillebrand, J., Luedeman, R. A., Coller, J. M., Johnson, N., Howlett, I. C., Geng, C., Ueda, R. et al. (2006). Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 52, 997-1009.
10. Beaulieu, C., Dyck R. and Cynader, M. (1992). Enrichment of glutamate in zinc-containing terminals of the cat visual cortex. NeuroReport 3, 861-864.
11. Behm-Ansmant, I., Rehwinkel, J., Doerks, T., Stark, A., Bork, P. and Izaurralde, E. (2006). mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev. 20, 1885-1898.
12. Brengues, M., Teixeira, D. and Parker, R. (2005). Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies. Science 310, 486-489.
13. Bush, A. I., Pettingell, W. H., Jr, Paradis, M. D. and Tanzi, R. E. (1994a). Modulation of A beta adhesiveness and secretase site cleavage by zinc. J. Biol. Chem. 269, 12152-12158.
14. Bush, A. I., Pettingell, W. H., Jr, de Paradis, M., Tanzi, R. E. and Wasco, W. (1994b). The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily. J. Biol. Chem. 269, 26618-26621.
15. Choi, D. W. and Koh, J. Y. (1998). Zinc and brain injury. Annu. Rev. Neurosci. 21, 347-375.
16. Cougot, N., Babajko, S. and Seraphin, B. (2004). Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell Biol. 165, 31-40.
17. Danscher, G., Jensen, K. B., Frederickson, C. J., Kemp, K., Andreasen, A., Juhl, S., Stoltenberg, M. and Ravid, R. (1997). Increased amount of zinc in the hippocampus and amygdala of Alzheimer's diseased brains: a proton-induced X-ray emission spectroscopic analysis of cryostat sections from autopsy material. J. Neurosci. Methods 76, 53-59.
18. Hillebrand, J., Barbee, S. A. and Ramaswami, M. (2007). P-body components, microRNA regulation, and synaptic plasticity. ScientificWorldJournal 7, 178-190.
19. Horne, Z. and Hesketh, J. (1990). Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution. Biochem. J. 268, 231-236.
20. Hwang, J. J., Park, M. H., Choi, S. Y. and Koh, J. Y. (2005). Activation of the Trk signaling pathway by extracellular zinc. Role of metalloproteinases. J. Biol. Chem. 280, 11995-12001.
21. Kiebler, M. A. and Bassell, G. J. (2006). Neuronal RNA granules: movers and makers. Neuron 51, 685-690.
22. Liu, J., Valencia-Sanchez, M. A., Hannon, G. J. and Parker, R. (2005). MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7, 719-723.
23. Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L. and Markesbery, W. R. (1998). Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurol. Sci. 158, 47-52.
24. McLardy, T. (1976). Anatomical rationale of ablative surgery for temporal lobe seizures and dyscontrol: suggested stereo-chemode chelate-blockade alternative. Acta Neurochir. (Wien), 119-124.
25. Nielsen, F. C., Nielsen, J., Kristensen, M. A., Koch, G. and Christiansen, J. (2002). Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domains. J. Cell Sci. 115, 2087-2097.
26. Sheth, U. and Parker, R. (2003). Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300, 805-808.
27. Szabo, A., Dalmau, J., Manley, G., Rosenfeld, M., Wong, E., Henson, J., Posner, J. B. and Furneaux, H. M. (1991). HuD, a paraneoplastic encephalomyelitis antigen, contain RNA binding domains and is homologous to Elav and Sex-lethal. Cell 67, 325-333.
28. Teixeira, D., Sheth, U., Valencia-Sanchez, M. A., Brengues, M. and Parker, R. (2005). Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA 11, 371-382.
29. Vessey, J. P., Vaccani, A., Xie, Y., Dahm, R., Karra, D., Kiebler, M. A. and Macchi, P. (2006). Dendritic localization of the translational repressor Pumilio 2 and its contribution to dendritic stress granules. J. Neurosci. 26, 6496-6508.