Imaging the deluded brain

European Archives of Psychiatry and Clinical Neuroscience

Volumn 258, Issue SUPPL. 5, 2008, Pages 76-80

  Knobel, Astrid ^a   Heinz, Andreas ^a   Voss, Martin ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Brain imaging; Delusions; Dopamine; Functional and structural disconnection; Schizophrenia

Indexed keywords

DOPAMINE;

AFFECT; ANISOTROPY; ATTENTION; BRAIN BLOOD FLOW; BRAIN FUNCTION; BRAIN METABOLISM; BRAIN RADIOGRAPHY; BRAIN REGION; BRAIN SIZE; CATATONIC SCHIZOPHRENIA; COGNITION; CONFERENCE PAPER; DELUSION; DIFFUSION TENSOR IMAGING; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; FRONTAL LOBE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLUCOSE METABOLISM; HEBEPHRENIA; HUMAN; LIMBIC SYSTEM; NEUROANATOMY; NEUROIMAGING; NEUROPATHOLOGY; PARANOID SCHIZOPHRENIA; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL LOBE;

ANIMALS; BRAIN; BRAIN MAPPING; COGNITION DISORDERS; DIAGNOSTIC IMAGING; DOPAMINE; HUMANS; SCHIZOPHRENIA, PARANOID;

EID: 55449094080     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-008-5008-0     Document Type: Conference Paper

References (43)

1. A Abi-Dargham J Rodenhiser D Printz Y Zea-Ponce R Gil LS Kegeles R Weiss TB Cooper JJ Mann RL Van Heertum JM Gorman M Laruelle 2000 Increased baseline occupancy of D2 receptors by dopamine in schizophrenia Proc Natl Acad Sci USA 97 8104 8109
2. PJ Basser J Mattiello D LeBihan 1994 MR diffusion tensor spectroscopy and imaging Biophys J 66 259 267
3. RP Bentall S Kaney 1989 Content specific information processing and persecutory delusions: an investigation using the emotional Stroop test Br J Med Psychol 62 Pt 4 355 364
4. NJ Blackwood RJ Howard RP Bentall RM Murray 2001 Cognitive neuropsychiatric models of persecutory delusions Am J Psychiatry 158 527 539
5. NJ Blackwood RP Bentall DH Ffytche A Simmons RM Murray RJ Howard 2004 Persecutory delusions and the determination of self-relevance: an fMRI investigation Psychol Med 34 591 596
6. A Carlsson LO Hansson N Waters ML Carlsson 1999 A glutamatergic deficiency model of schizophrenia Br J Psychiatry Suppl 37 2 6
7. PR Corlett GD Honey MR Aitken A Dickinson DR Shanks AR Absalom M Lee E Pomarol-Clotet GK Murray PJ McKenna TW Robbins ET Bullmore PC Fletcher 2006 Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis Arch Gen Psychiatry 63 611 621
8. PR Corlett GK Murray GD Honey MRF Aitken DR Shanks TW Robbins ET Bullmore A Dickinson PC Fletcher 2007 Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions Brain 130 2387 2400
9. H Fujiwara C Namiki K Hirao J Miyata M Shimizu H Fukuyama N Sawamoto T Hayashi T Murai 2007 Anterior and posterior cingulum abnormalities and their association with psychopathology in schizophrenia: A diffusion tensor imaging study Schizophr Res 95 215 222
10. RE Gur V Maany PD Mozley C Swanson W Bilker RC Gur 1998 Subcortical MRI volumes in neuroleptic-naive and treated patients with schizophrenia Am J Psychiatry 155 1711 1717
11. A Heinz RC Saunders BS Kolachana DW Jones JG Gorey J Bachevalier DR Weinberger 1999 Striatal dopamine receptors and transporters in monkeys with neonatal temporal limbic damage Synapse 32 2 71 79
12. Heinz A, Weinberger DR (2000) Schizophrenia: the neurodevelopmental hypothesis. Current concepts in psychiatry (Psychiatrie der Gegenwart). Springer, Berlin, pp 89-104
13. A Heinz 2002 Dopaminergic dysfunction in alcoholism and schizophrenia-psychopathological and behavioral correlates Eur Psychiatry 17 9 16
14. Jaspers K (1965) Allgemeine Psychopathologie. 8. Auflage. Springer Berlin, Heidelberg, New York
15. G Juckel F Schlagenhauf M Koslowski T Wustenberg A Villringer B Knutson J Wrase A Heinz 2006 Dysfunction of ventral striatal reward prediction in schizophrenia Neuroimage 15 29 409 416
16. P Kalus C Buri J Slotboom J Gralla L Remonda T Dierks WK Strik G Schroth C Kiefer 2004 Volumetry and diffusion tensor imaging of hippocampal subregions in schizophrenia NeuroReport 15 5 867 871
17. P Kalus J Slotboom J Gallinat R Wiest C Ozdoba A Federspiel WK Strik C Buri G Schroth C Kiefer 2005 The amygdala in schizophrenia: a trimodal magnetic resonance imaging study Neurosci Lett 375 3 151 156
18. RD Kaplan H Szechtman S Franco B Szechtman C Nahmias ES Garnett S List JM Cleghorn 1993 Three clinical syndromes of schizophrenia in untreated subjects: relation to brain glucose activity measured by positron emission tomography (PET) Schizophr Res 11 47 54
19. S Kapur 2003 Psychosis as a state of aberrant salience: a framework linking biology, pheno- menology, and pharmacology in schizophrenia Am J Psychiatry 160 13 23
20. LS Kegeles A Abi-Dargham Y Zea-Ponce J Rodenhiser-Hill JJ Mann RL Van Heertum TB Cooper A Carlsson M Laruelle 2000 Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia Biol Psychiatry 48 7 627 640
21. T Kienast A Heinz 2006 Dopamine and the diseased brain CNS Neurol Disord Drug Targets 5 109 131
22. B Knutson GW Fong CM Adams JL Varner D Hommer 2001 Dissociation of reward anticipation and outcome with event-related fMRI NeuroReport 12 3683 3687
23. B Knutson JM Bjork GW Fong D Hommer VS Mattay DR Weinberger 2004 Amphetamine modulates human incentive processing Neuron 43 2 261 269
24. T Kohno T Shiga I Kusumi T Matsuyama H Kageyama C Katoh T Koyama N Tamaki 2006 Left temporal perfusion associated with suspiciousness score on the Brief Psychiatric Rating Scale in schizophrenia Psychiatry Res 30 147 163 171
25. M Kubicki H Park CF Westin RV Mulkern SE Maier M Niznikiewicz EE Connor JJ Levitt M Frumin R Kikinis FA Jolesz RW McCarley ME Shenton 2005 DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity Neuroimage 26 1109 1118
26. JS Kwon RW McCarley Y Hirayasu JE Anderson IA Fischer R Kikinis FA Jolesz ME Shenton 1999 Left planum temporale volume reduction in schizophrenia Arch Gen Psychiatry 56 142 148
27. PF Liddle KJ Friston CD Frith SR Hirsch T Jones RSJ Frackowiak 1992 Patterns of cerebral blood flow in schizophrenia Br J Psychiatry 160 179 186
28. SA Mitelman Y Torosjan RE Newmark JS Schneiderman KW Chu AM Brickman MM Haznedar EA Hazlett CY Tang L Shihabuddin MS Buchsbaum 2007 Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: A diffusion tensor imaging survey Schizophr Res 92 211 224
29. RM Murray SW Lewis 1987 Is schizophrenia a neurodevelopmental disorder? Br Med J (Clin Res Ed) 295 681 682
30. PG Nestor T Onitsuka RJ Gurrera M Niznikiewicz M Frumin ME Shenton RW McCarley 2007 Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia Schizophr Res 91 103 106
31. ML Phillips C Senior AS David 2000 Perception of threat in schizophrenics with persecutory delusions: an investigation using visual scan paths Psychol Med 30 157 167
32. BK Puri SK Lekh KS Nijran MS Bagary AJ Richardson 2001 SPECT neuroimaging in schizophrenia with religious delusions Int J Psychophysiol 40 2 143 148
33. DJ Ragland JN Valdez J Loughead RC Gur RE Gur 2006 Functional magnetic resonance imaging of internal source monitoring in schizophrenia: Recognition with and without recollection Schizophr Res 87 160 171
34. TA Russell E Reynaud K Kucharska-Pietura C Ecker PJ Benson F Zelaya V Giampietro M Brammer A David ML Phillips 2007 Neural responses to dynamic expressions of fear in schizophrenia Neuropsychologia 45 1 107 123
35. O Sabri R Erkwoh M Schreckenberger A Owega H Sass U Buell 1997 Correlation of positive symptoms exclusively to hyperperfusion or hypoperfusion of cerebral cortex in never-treated schizophrenics Lancet 349 1735 1739
36. W Schultz P Dayan PR Montague 1997 A neural substrate of prediction and reward Science 275 1593 1599
37. ME Shenton CC Dickey M Frumin RW McCarley 2001 A review of MRI findings in schizophrenia Schizophr Res 49 1 52
38. LR Skelly V Calhoun AM Shashwath K Jinsuh DH Mathalon GD Pearlson 2008 Diffusion Tensor imaging in schizophrenia: Realtionship to symptoms Schizophr Res 98 157 162
39. PR Szeszko RM Bilder T Lencz S Pollack JM Alvir M Ashtari H Wu JA Lieberman 1999 Investigation of frontal lobe subregions in first-episode schizophrenia Psychiatry Res 90 1 15
40. PR Szeszko DG Robinson M Ashtari J Vogel J Betensky S Sevy BA Ardekani T Lencz AK Malhotra J McCormack R Miller KO Lim H Gunduz-Bruce JM Kane RM Bilder 2008 Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia Neuropsychopharmacology 33 976 984
41. DR Weinberger 1987 Implications of normal brain development for the pathogenesis of schizophrenia Arch Gen Psychiatry 44 660 669
42. LM Williams P Das AW Harris BB Liddell MJ Brammer G Olivieri D Skerrett ML Phillips AS David A Peduto E Gordon 2004 Dysregulation of arousal and amygdala-prefrontal systems in paranoid schizophrenia Am J Psychiatry 161 480 489
43. Y Zhou N Shu Y Liu M Song Y Hao H Liu C Yu Z Liu T Jiang 2008 Altered resting-state functional connectivity and anatomical connectivity of hippocampus in schizophrenia Schizophr Res 100 1-3 120 132