Large-Scale Production of Major House Dust Mite Allergen Der f 2 Mutant (C8/119S) in Escherichia coli

Journal of Bioscience and Bioengineering

Volumn 106, Issue 4, 2008, Pages 387-392

  Koyanagi, Satoshi ^a   Maeda, Toshihiro ^a   Murakami, Toshio ^a   Kawatsu, Kenjirou ^a   Sugawara, Keishin ^a   Miyatsu, Yoshinobu ^a   Mizokami, Hiroshi ^a  

^a Chemo Sero Therapeutic Research Institute   (Japan)

Author keywords

C8 119S; Der f 2; Escherichia coli; fermentation; mite allergen; thermal induction

Indexed keywords

ANTIGENS; BIOCHEMICAL ENGINEERING; CHROMATOGRAPHIC ANALYSIS; DUST; PURIFICATION; WATER POLLUTION;

A STABLES; ALLERGIC DISEASES; C8/119S; DER F 2; E. COLI; EXPRESSION SYSTEMS; HIGH COSTS; HIGH TEMPERATURES; HOUSE DUSTS; IMMUNOLOGICAL PROPERTIES; INCLUSION BODIES; INDUSTRIAL PRODUCTIONS; LOW COSTS; MITE ALLERGEN; PURIFICATION PROCESSES; RECOMBINANT E. COLI; REFOLDING; THERMAL INDUCTION; WESTERN BLOTTING;

ESCHERICHIA COLI;

HOUSE DUST ALLERGEN; PROTEIN C8/119S; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL INCLUSION; CONTROLLED STUDY; ESCHERICHIA COLI; LARGE SCALE PRODUCTION; LOW TEMPERATURE; MUTANT; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; WESTERN BLOTTING;

ALLERGENS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; BIOTECHNOLOGY; CHROMATOGRAPHY; CHROMATOGRAPHY, GEL; ESCHERICHIA COLI; FERMENTATION; HYPERSENSITIVITY; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; PROTEIN DENATURATION; PROTEIN FOLDING;

ACARI; ESCHERICHIA COLI; PYROGLYPHIDAE;

EID: 55349096496     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.106.387     Document Type: Article

References (21)

1. Miyamoto T., Oshima S., Ishizaki T., and Sato S.H. Allergenic identity between the common floor mite (Dermatophagoides farinae Hughes, 1961) and house dust as a causative antigen in bronchial asthma. J. Allergy 42 (1968) 14-28
2. Van-Bever H.P., and Stevens W.J. Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus). Eur. Respir. J. 5 (1992) 318-322
3. Mchiels J.J., Somville M.A., Lebrum P.M., Lebecque S.J., Jacquemin M.G., and Saint-Remy J.M. Allergic bronchial asthma due to Dermatophagoides pteronyssinus hypersensitivity can be efficiently treated by inoculation of allergen-antibody complexes. J. Clin. Invest. 85 (1990) 1024-1035
4. Olsen O., Larsen K., Jacobsen L., and Svenden U. A one year placebo-controlled double-blind house dust mite immunotherapy study in asthmatic adults. Allergy 52 (1997) 853-859
5. Pichler C., Marquardsen A., Sparholt S., Lowenstein H., Bircher A., Bischof M., and Pichler W.J. Specific immunotherapy with Dermatophagoides pteronissinus and D farinae results in decreased bronchial hyperreactivity. Allergy 52 (1997) 274-283
6. Ewan P.W., Alexander M.M., Snape C., Ind P.W., Agrell B., and Dreborg S. Effective hyposensitization in allergic rhinitis using a potent partially purified extract of house dust mite. Clin. Allergy 18 (1988) 501-508
7. Haida M., Okudaira H., Ogita T., Ito K., Miyamoto T., Nakajima T., and Hongo O. Allergens of the house dust mite Dermatophagoides farinae-Immunochemical studies of four allergenic fractions. J. Allergy Clin. Immunol. 75 (1985) 686-692
8. Yuuki T., Okumura Y., Ando T., Yamakawa H., Suko M., Haida M., and Okudaira H. Cloning and sequencing of cDNAs corresponding to mite major allergen Der f II. Arerugi 39 (1990) 557-561
9. Nishiyama C., Yuuki T., Usui Y., Iwamoto N., Okumura Y., and Okudaira H. Effects of amino acid variations in recombinant Der f II on its human IgE and mouse IgG recognition. Int. Arch. Allergy Immunol. 105 (1994) 62-69
10. Nishiyama C., Fukada M., Usui Y., Iwamoto N., Yuuki T., Okumura Y., and Okudaira H. Analysis of the IgE-epitope of Der f 2, a major mite allergen, by in vitro mutagenesis. Mol. Immunol. 32 (1995) 1021-1029
11. Yuuki T., Okumura Y., Ando T., Yamakawa H., Suko M., Haida M., and Okudaira H. Cloning and expression of cDNA coding for the major house dust mite allergen Der f II in Escherichia coli. Agric. Biol. Chem. 55 (1991) 1233-1238
12. Ichikawa S., Hatanaka H., Yuuki T., Iwamoto N., Kojima S., Nishiyama C., Ogura K., Okumura Y., and Inagaki F. Solution structure of Der f 2, the major mite allergen for atopic diseases. J. Biol. Chem. 273 (1998) 356-360
13. Noguchi E., Shibasaki M., Nishiyama C., Okumura Y., and Takita H. IgE responsiveness to Dermatophagoides farinae in young asthmatic children: IgE binding study using recombinant allergens of Der f 1, Der f 2 and mutant proteins of Der f 2. Int. Arch. Allergy Immunol. 110 (1996) 380-387
14. Takai T., Yokota T., Yasue M., Nishiyama C., Yuuki T., Mori A., Okudaira H., and Okumura Y. Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy. Nat. Biotechnol. 15 (1997) 754-758
15. Korematsu S., Tanaka Y., Hosoi S., Koyanagi S., Yokota T., Mikami B., and Minato N. C8/119S mutation of major mite allergen Derf-2 leads to degenerate secondary structure and molecular polymerization and induces potent and exclusive Th1 cell differentiation. J. Immunol. 165 (2000) 2895-2902
16. Takai T., Ichikawa S., Yokota T., Hatanaka H., Inagaki F., and Okumura Y. Unlocking the allergenic structure of the major house dust mite allergen Der f 2 by elimination of key interactions. FEBS Lett. 484 (2000) 102-107
17. Ikehara M., Ohtsuka E., Tokunaga T., Taniyama Y., Iwai S., Kitano K., Miyamoto S., Ohgi T., Sakuragawa Y., Fujiyama K., and 12 other authors. Synthesis of a gene for human growth hormone and its expression in Escherichia coli. Proc. Natl. Acad. Sci. USA 81 (1984) 5956-5960
18. Takai T., Yuuki T., Okumura Y., Mori A., and Okudaira H. Determination of the N- and C-terminal sequences required to bind human IgE of the major house dust mite allergen Der f 2 and epitope mapping for monoclonal antibodies. Mol. Immunol. 34 (1997) 255-261
19. Nishiyama C., Hatanaka H., Ichikawa S., Fukada M., Akagawa M., Yuuki T., Yokota T., Inagawa F., and Okumura Y. Analysis of human IgE epitope of Der f 2 with anti-Der f 2 mouse monoclonal antibodies. Mol. Immunol. 36 (1999) 53-60
20. Pan S.H., and Malcolm B.A. Reduced background expression and improved plasmid stability with pET vectors in BL21 (DE3). BioTechniques 29 (2000) 1234-1238
21. Nishiyama C., Yuuki T., Takai T., Okumura Y., and Okudaira H. Determination of three disulfide bonds in a major house dust mite allergen, Der f II. Int. Arch. Allergy Immunol. 101 (1993) 159-166