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Volumn 99, Issue 9, 2008, Pages 1387-1394

Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours

Author keywords

Advanced solid tumours; Angiogenesis; Gemcitabine; Lymphoma; Motesanib diphosphate; Pharmacokinetics

Indexed keywords

ANTINEOPLASTIC AGENT; GEMCITABINE; MOTESANIB; UNCLASSIFIED DRUG;

EID: 55249120960     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604723     Document Type: Article
Times cited : (16)

References (30)
  • 1
    • 33745621338 scopus 로고    scopus 로고
    • Pharmacokinetic evaluation of gemcitabine and 2′,2′- difluorodeoxycytidine-5′-triphosphate after prolonged infusion in patients affected by different solid tumors
    • Cattel L, Airoldi M, Delprino L, Passera R, Milla P, Pedani F (2006) Pharmacokinetic evaluation of gemcitabine and 2′,2′- difluorodeoxycytidine-5′-triphosphate after prolonged infusion in patients affected by different solid tumors. Ann Oncol 17: v142-v147
    • (2006) Ann Oncol , vol.17
    • Cattel, L.1    Airoldi, M.2    Delprino, L.3    Passera, R.4    Milla, P.5    Pedani, F.6
  • 2
    • 55249098566 scopus 로고    scopus 로고
    • Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 (2006) Cancer Therapy Evaluation Program, National Cancer Institute. Available at: Updated August 9, 2006. Accessed June 18, 2008
    • Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 (2006) Cancer Therapy Evaluation Program, National Cancer Institute. Available at: http://ctep.cancer.gov/reporting/ctc_v30.html Updated August 9, 2006. Accessed June 18, 2008
  • 4
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9: 669-676
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 5
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J, Shing Y (1992) Angiogenesis. J Biol Chem 267: 10931-10934
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 6
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson III AB (2007) Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25: 1539-1544
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson III, A.B.8
  • 8
    • 0037087531 scopus 로고    scopus 로고
    • Inhibition of KIT tyrosine kinase activity: A novel molecular approach to the treatment of KIT-positive malignancies
    • Heinrich MC, Blanke CD, Druker BJ, Corless CL (2002) Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 20: 1692-1703
    • (2002) J Clin Oncol , vol.20 , pp. 1692-1703
    • Heinrich, M.C.1    Blanke, C.D.2    Druker, B.J.3    Corless, C.L.4
  • 9
    • 36048982143 scopus 로고    scopus 로고
    • Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer
    • Herbst RS, O'Neill VJ, Fehrenbacher L, Belani CP, Bonomi PD, Hart L, Melnyk O, Ramies D, Lin M, Sandler A (2007) Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancer. J Clin Oncol 25: 4743-4750
    • (2007) J Clin Oncol , vol.25 , pp. 4743-4750
    • Herbst, R.S.1    O'Neill, V.J.2    Fehrenbacher, L.3    Belani, C.P.4    Bonomi, P.D.5    Hart, L.6    Melnyk, O.7    Ramies, D.8    Lin, M.9    Sandler, A.10
  • 10
    • 19844364244 scopus 로고    scopus 로고
    • Angiogenesis and lung cancer: Prognostic and therapeutic implications
    • Herbst RS, Onn A, Sandler A (2005) Angiogenesis and lung cancer: prognostic and therapeutic implications. J Clin Oncol 23: 3243-3256
    • (2005) J Clin Oncol , vol.23 , pp. 3243-3256
    • Herbst, R.S.1    Onn, A.2    Sandler, A.3
  • 14
    • 55249105391 scopus 로고    scopus 로고
    • Kindler HL, Niedzwiecki D, Hollis D, Oraefo E, Schrag D, Hurwitz H, McLeod HL, Mulcahy MF, Schilsky RL, Goldberg RM, B C.a.L.G (2007) A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) vs gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): a preliminary analysis of Cancer and Leukemia Group B (CALGB) [abstract]. J Clin Oncol 25: 4508
    • Kindler HL, Niedzwiecki D, Hollis D, Oraefo E, Schrag D, Hurwitz H, McLeod HL, Mulcahy MF, Schilsky RL, Goldberg RM, B C.a.L.G (2007) A double-blind, placebo-controlled, randomized phase III trial of gemcitabine (G) plus bevacizumab (B) vs gemcitabine plus placebo (P) in patients (pts) with advanced pancreatic cancer (PC): a preliminary analysis of Cancer and Leukemia Group B (CALGB) [abstract]. J Clin Oncol 25: 4508
  • 15
    • 55249106831 scopus 로고    scopus 로고
    • Manegold C, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, Leighl N, Mezger J, Archer V, Reck M, group t.B.s (2005) Randomised, double-blind multicentre phase III study of bevacizumab in combination with cisplatin and gemcitabine in chemotherapy-naïve patients with advanced or recurrent non-squamous non-small cell lung cancer (NSCLC): BO17704 [abstract]. J Clin Oncol 25: LBA7514
    • Manegold C, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, Leighl N, Mezger J, Archer V, Reck M, group t.B.s (2005) Randomised, double-blind multicentre phase III study of bevacizumab in combination with cisplatin and gemcitabine in chemotherapy-naïve patients with advanced or recurrent non-squamous non-small cell lung cancer (NSCLC): BO17704 [abstract]. J Clin Oncol 25: LBA7514
  • 16
    • 55249098281 scopus 로고    scopus 로고
    • Medical Dictionary for Regulatory Activities Terminology (MedDRA) version 6.1 (2008) International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use ICH, MedDRA/MSSO resources page. Available at: Updated October, 2003. Accessed June 18, 2008
    • Medical Dictionary for Regulatory Activities Terminology (MedDRA) version 6.1 (2008) International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). MedDRA/MSSO resources page. Available at: http://www.meddramsso.com/MSSOWeb/index.htm Updated October, 2003. Accessed June 18, 2008
  • 22
    • 33749000911 scopus 로고    scopus 로고
    • Polverino A, Coxon A, Starnes C, Diaz Z, Demelfi T, Wang L, Bready J, Estrada J, Cattley R, Kaufman S, Chen D, Gan Y, Kumar G, Meyer J, Neervannan S, Alva G, Talvenheimo J, Montestruque S, Tasker A, Patel V, Radinsky R, Kendall R (2006) AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts. Cancer Res 66: 8715-8721
    • Polverino A, Coxon A, Starnes C, Diaz Z, Demelfi T, Wang L, Bready J, Estrada J, Cattley R, Kaufman S, Chen D, Gan Y, Kumar G, Meyer J, Neervannan S, Alva G, Talvenheimo J, Montestruque S, Tasker A, Patel V, Radinsky R, Kendall R (2006) AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and Kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts. Cancer Res 66: 8715-8721
  • 29
    • 0038544202 scopus 로고    scopus 로고
    • Platelet-derived growth factor signaling and human cancer
    • Yu J, Ustach C, Kim HR (2003) Platelet-derived growth factor signaling and human cancer. J Biochem Mol Biol 36: 49-59
    • (2003) J Biochem Mol Biol , vol.36 , pp. 49-59
    • Yu, J.1    Ustach, C.2    Kim, H.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.