Optimization of labile esters for esterase-assisted accumulation of nitroxides into cells: A model for in vivo EPR imaging

Bioconjugate Chemistry

Volumn 19, Issue 10, 2008, Pages 2068-2071

  Burks, Scott R ^a,b,c   Ni, Jiahong ^a   Muralidharan, Sukumaran ^a   Coop, Andrew ^d   Kao, Joseph P Y ^a,b,c,e   Rosen, Gerald M ^a,c,d,e  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CARBOXYLATION; CHAINS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESTERS; PARAMAGNETIC RESONANCE;

BLOOD-BRAIN BARRIER; CELL MODEL; CHAINS LENGTH; CULTURED CELL; ELECTRON PARAMAGNETIC RESONANCE IMAGING; IMAGING AGENT; IN-VIVO; NITROXIDES; OPTIMISATIONS; REAL- TIME;

NITROGEN OXIDES;

CARBOXYLIC ACID DERIVATIVE; ESTER DERIVATIVE; ESTERASE; METHYL GROUP; NITROXIDE DERIVATIVE;

ARTICLE; BIOACCUMULATION; BLOOD BRAIN BARRIER; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; HYDROLYSIS; IN VIVO STUDY; ISOMER; LIPOPHILICITY; MODEL; QUANTITATIVE ANALYSIS;

ANIMALIA;

EID: 55249115090     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc8001562     Document Type: Article

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