O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis

Biochemistry

Volumn 47, Issue 44, 2008, Pages 11606-11615

  O'Leary, Seán E ^a   Jurgenson, Christopher T ^a   Ealick, Steven E ^a   Begley, Tadhg P ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; ASSOCIATION REACTIONS; BINDING SITES; CIVIL AVIATION; ENZYMES; ORGANIC ACIDS; PROTEINS; REACTION KINETICS; SULFUR;

A STABLES; ACTIVE SITES; CARRIER PROTEINS; CHEMICAL MECHANISMS; CONFORMATIONAL CHANGES; IN-VIVO; KINETIC CHARACTERIZATIONS; KINETIC PATHWAYS; MYCOBACTERIUM TUBERCULOSIS; ORDERS OF MAGNITUDES; RAPID EQUILIBRIUMS; SULFUR TRANSFERS; SYNTHASE;

SUBSTRATES;

ACRYLIC ACID; ALPHA AMINOACRYLATE; CARRIER PROTEIN; CYSTEINE SYNTHASE; ISOENZYME; PHOSPHOSERINE; PROTEIN CYSM; SULFUR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXYLATION; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

CARRIER PROTEINS; CYSTEINE; CYSTEINE SYNTHASE; KINETICS; MYCOBACTERIUM TUBERCULOSIS; OXIDATIVE STRESS; PHOSPHOSERINE; SERINE; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 55249100956     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8013664     Document Type: Article

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