Racial differences in microbleed prevalence in primary intracerebral hemorrhage

Neurology

Volumn 71, Issue 15, 2008, Pages 1176-1182

  Copenhaver, B R ^a   Hsia, A W ^a,b   Merino, J G ^c   Burgess, R E ^a   Fifi, J T ^b   Davis, L ^d   Warach, S ^d   Kidwell, C S ^a,b,e  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON HOSPITAL CENTER   (United States)

^c SUBURBAN HOSPITAL   (United States)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^e Washington Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; BRAIN HEMORRHAGE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HEALTH CENTER; HOSPITAL PATIENT; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; POPULATION; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; BRAIN CIRCULATION; CAUCASIAN; CLINICAL TRIAL; ETHNOLOGY; MICROCIRCULATION; MIDDLE AGED; MULTICENTER STUDY; NEGRO; PATHOPHYSIOLOGY; PILOT STUDY; PREVALENCE; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICS; STROKE; UNITED STATES;

BIOLOGICAL MARKER;

AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; BIOLOGICAL MARKERS; CEREBROVASCULAR CIRCULATION; DISTRICT OF COLUMBIA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; INTRACRANIAL HEMORRHAGES; MALE; MARYLAND; MICROCIRCULATION; MIDDLE AGED; PILOT PROJECTS; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; STROKE;

EID: 55249096203     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000327524.16575.ca     Document Type: Article

References (19)

1. Hill MD, Silver FL, Austin PC, Tu JV. Rate of stroke recurrence in patients with primary intracerebral hemorrhage. Stroke 2000;31:123-127.
2. Woo D, Sauerbeck LR, Kissela BM, et al. Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke 2002;33:1190-1195.
3. Greenberg SM, Vonsattel JP, Segal AZ, et al. Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy. Neurology 1998;50: 961-965.
4. Fazekas F, Kleinert R, Roob G, et al. Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of microangio-pathyrelated microbleeds. AJNR Am J Neuroradiol 1999;20:637-642.
5. Greenberg SM, O'Donnell HC, Schaefer PW, Kraft E. MRI detection of new hemorrhages: potential marker of progression in cerebral amyloid angiopathy. Neurology 1999;53:1135-1138.
6. Roob G, Lechner A, Schmidt R, Flooh E, Hartung HP, Fazekas F. Frequency and location of microbleeds in patients with primary intracerebral hemorrhage. Stroke 2000;31:2665-2669.
7. Jeerakathil T, Wolf PA, Beiser A, et al. Cerebral microbleeds: prevalence and associations with cardiovascular risk factors in the Framingham Study. Stroke 2004;35: 1831-1835.
8. Roob G, Schmidt R, Kapeller P, Lechner A, Hartung HP, Fazekas F. MRI evidence of past cerebral microbleeds in a healthy elderly population. Neurology 1999; 52:991-994.
9. Kwa VI, Franke CL, Verbeeten B, Jr, Stam J. Silent intra-cerebral microhemorrhages in patients with ischemic stroke: Amsterdam Vascular Medicine Group. Ann Neurol 1998;44:372-377.
10. Hanyu H, Tanaka Y, Shimizu S, et al. Cerebral microbleeds in Binswanger's disease: a gradient-echo T2*-weighted magnetic resonance imaging study. Neurosci Lett 2003;340:213-216.
11. Kinoshita T, Okudera T, Tamura H, Ogawa T, Hatazawa J. Assessment of lacunar hemorrhage associated with hypertensive stroke by echo-planar gradient-echo T2*-weighted MRI. Stroke 2000;31:1646-1650.
12. Tsushima Y, Tamura T, Unno Y, Kusano S, Endo K. Multifocal low-signal brain lesions on T2*-weighted gradient-echo imaging. Neuroradiol 2000;42:499-504.
13. Hsia AW, Warach S, Fifi J, et al. Hypertension, but not diabetes mellitus, is associated with cerebral microbleeds in patients with acute ischemic stroke. Stroke 2007;38:530.
14. Greenberg SM, Finklestein SP, Schaefer PW. Petechial hemorrhages accompanying lobar hemorrhage: detection by gradient-echo MRI. Neurology 1996;46:1751-1754.
15. Hsia AW, Huang L, Copenhaver BR, Schaewe TJ, Kidwell CS. Hemorrhage detection, both acute and chronic, is comparable on 1.5 vs 3.0 Tesla magnet strength Stroke 2008 (in press).
16. Fazekas F, Barkhof F, Wahlund LO, et al. CT and MRI rating of white matter lesions. Cerebrovasc Dis 2002;13 suppl 2:31-36.
17. Vernooij MW, van der Lugt A, Ikram MA, et al. Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study. Neurology 2008;70:1208-1214.
18. Cordonnier C, Al-Shahi Salman R, Wardlaw J. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain 2007;130:1988-2003.
19. Flaherty ML, Woo D, Haverbusch M, et al. Racial variations in location and risk of intracerebral hemorrhage. Stroke 2005;36:934-937.