Drosophila mechanotransduction linking proteins and functions

Fly

Volumn 1, Issue 4, 2007, Pages 238-241

  Albert, Jörg T ^a   Nadrowksi, Björn ^a   Göpfert, Martin C ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Auditory transducer; Biophysics; Chordotonal organ; Gating spring model; Insect hearing; Ion channel

Indexed keywords

HEXAPODA; VERTEBRATA;

DROSOPHILA PROTEIN;

ANIMAL; ARTICLE; DROSOPHILA MELANOGASTER; EAR; HEARING; MECHANOTRANSDUCTION; PHYSIOLOGY;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EAR; HEARING; MECHANOTRANSDUCTION, CELLULAR;

EID: 55249088375     PISSN: 19336934     EISSN: 19336942     Source Type: Journal    
DOI: 10.4161/fly.4990     Document Type: Article

References (28)

1. French AS. Transduction mechanisms of mechanosensilla. Ann Rev Entomol 1988; 33:39-58.
2. Walker RG, Willingham AT, Zuker CS. A Drosophila mechanosensory transduction channel. Science 2000; 287:2229-34.
3. Kim J, Chung YD, Park DY, Choi S, Shin DW, Soh H, Lee HW, Son W, Yim J, Park CS, Kernan MJ, Kim C. A TRPV family ion channel required for hearing in Drosophila. Nature 2003; 424:81-4.
4. Gong Z, Son W, Chung YD, Kim J, Shin DW, McClung CA, Lee Y, Lee HW, Chang DJ, Kaang BK, Cho H, Oh U, Hirsch J, Kernan MJ, Kim C. Two interdependent TRPV channel subunits, Inactive and Nanchung, mediate hearing in Drosophila. J Neurosci 2004; 24:9059-66.
5. Gillespie PG, Walker RG. Molecular basis of mechanosensory transduction. Nature 2001; 413:194-202.
6. Göpfert MC, Albert JT, Nadrowski BM, Kamikouchi A. Specification of auditory sensitivity by Drosophila TRP channels. Nat Neurosci 2006; 9:999-1000.
7. Kernan MJ. Mechanosensory and auditory transduction in Drosophila. Pflugers Arch 2007; 454:703-20.
8. Ernstrom GG, Chalfie M. Genetics of sensory mechanotransduction. Annu Rev Genet 2002; 36:411-53.
9. Christensen AP, Corey DP. TRP channels in mechanosensation: Direct or indirect activation? Nat Rev Neurosci 2007; 8:510-21.
10. Hille B. Ion channels of excitable membranes. 3rd ed. Sunderland, MA: Sinauer, 2001.
11. Sukharev S, Corey DP. Mechanosensitive channels: Multiplicity of families and gating paradigms. Sci STKE 2004; 3:re4.
12. Ranganathan R, Malicki DM, Zuker CS. Signal transduction in Drosophila photoreceptors. Annu Rev Neurosci 1995; 18:283-317.
13. Corey DP, Hudspeth AJ. Kinetics of the receptor current in bullfrog saccular hair cells. J Neurosci 1983; 3:962-76.
14. Howard J, Hudspeth AJ. Mechanical relaxation of the hair bundle mediates adaptation in mechanoelectrical transduction by the bullfrog's saccular hair cell. Proc Natl Acad Sci USA 1987; 84:3064-8.
15. Howard J, Hudspeth AJ. Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell. Neuron 1988; 1:189-99.
16. Albert JT, Nadrowski BM, Göpfert MC. Mechanical signatures of transducer gating in the Drosophila ear. Curr Biol 2007; 17:1000-6.
17. Göpfert MC, Robert D. Turning the key on Drosophila audition. Nature 2001; 411:908.
18. Göpfert MC, Robert D. The mechanical basis of Drosophila audition. J Exp Biol 2002; 205:1199-208.
19. Keil TA. Functional morphology of insect mechanoreceptors. Microsc Res Tech 1997; 39:506-31.
20. Eberl DF. Feeling the vibes: Chordotonal mechanisms in insect hearing. Curr Opin Neurobiol 1999; 9:389-93.
21. Yack JE. The structure and function of auditory chordotonal organs in insects. Microsc Res Tech 2004; 63:315-37.
22. Hudspeth AJ, Choe Y, Mehta AD, Martin P. Putting ion channels to work: Mechanoelectrical transduction adaptation and amplification by hair cells. Proc Natl Acad Sci USA 2000; 97:11765-72.
23. Albert JT, Nadrowski B, Kamikouchi A, Göpfert MC. Mechanical tracing of protein function in the Drosophila ear. Nat Protoc 2006; ((Published online November 3) 10.1038/ nprot.2006.364).
24. Kernan M, Cowan D, Zuker C. Genetic dissection of mechanosensory transduction: Mechanoreception-defective mutations of Drosophila. Neuron 1994; 12:1195-206.
25. Eberl DF, Duyk GM, Perrimon N. A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proc Natl Acad Sci USA 1997; 94:14837-42.
26. Armstrong JD, Texada MJ, Munjaal R, Baker DA, Beckingham KM. Gravitaxis in Drosophila melanogaster: A forward genetic screen. Genes Brain Behav 2006; 5:222-39.
27. Eberl DF, Hardy RW, Kernan MJ. Genetically similar transduction mechanisms for touch and hearing in Drosophila. J Neurosci 2000; 20:5981-8.
28. Kamikouchi A, Shimada T, Ito K. Comprehensive classification of the auditory sensory projections in the brain of the fruit fly Drosophila melanogaster. J Comp Neurol 2006; 499:317-56.