Evaluating the tolerability and efficacy of etanercept compared to triamcinolone acetonide for the intralesional treatment of keloids

Journal of Drugs in Dermatology

Volumn 7, Issue 8, 2008, Pages 757-761

  Berman, Brian ^a   Patel, Jitendrakumar K ^a   Perez, Oliver A ^a   Viera, Martha H ^a   Amini, Sadegh ^a   Block, Samantha ^a   Zell, Deborah ^a   Tadicherla, Sujatha ^a   Villa, Adriana ^a   Ramirez, Claudia ^a   De Araujo, Tami ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN G; NONSTEROID ANTIINFLAMMATORY AGENT; TNFR FC FUSION PROTEIN; TNFR-FC FUSION PROTEIN; TRIAMCINOLONE ACETONIDE; TUMOR NECROSIS FACTOR RECEPTOR;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLICULITIS; HUMAN; INJECTION; MALE; MIDDLE AGED; PATHOLOGY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SKIN;

ACNE KELOID; ADULT; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FEMALE; HUMANS; IMMUNOGLOBULIN G; INJECTIONS; MALE; MIDDLE AGED; PRURITUS; RECEPTORS, TUMOR NECROSIS FACTOR; SKIN; TRIAMCINOLONE ACETONIDE;

EID: 55249083612     PISSN: 15459616     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Berman B, Frankel S, Villa AM, et al. Double-blind, randomized, placebo-controlled, prospective study evaluating the tolerability and effectiveness of imiquimod applied to postsurgical excisions on scar cosmesis. Dermatol Surg. 2005;31:1399-1403.
2. Meier K, Nanney LB. Emerging new drugs for scar reduction. Expert Opin Emerg Drugs. 2006;11:39-47.
3. Al-Attar A, Mess S, Thomassen JM, et al. Keloid pathogenesis and treatment. Plast Reconstr Surg. 2006;117:286-300. (Pubitemid 44391579)
4. Rapala K. The effect of tumor necrosis factor-alpha on wound healing. An experimental study. Ann Chir Gynaecol Suppl. 1996;211:1-53. (Pubitemid 26189116)
5. English RS, Shenefelt PD. Keloids and hypertrophic scars. Dermatol Surg. 1999;25:631-638. (Pubitemid 29383470)
6. Berman B, Bieley HC. Adjunct therapies to surgical management of keloids. Dermatol Surg. 1996;22:126-130. (Pubitemid 26069616)
7. Slemp AE, Kirschner RE. Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and management. Curr Opin Pediatr. 2006;18:396-402. (Pubitemid 44258997)
8. Devlin-Rooney K, James W. Management and prevention of abnormal scars. Nurs Stand. 2005;19:45-54.
9. Kelly AP. Medical and surgical therapies for keloids. Dermatol Ther. 2004;17:212-218. (Pubitemid 38656914)
10. Leventhal D, Furr M, Reiter D. Treatment of keloids and hypertrophic scars: a meta-analysis and review of the literature. Arch Facial Plast Surg. 2006;8:362-368. (Pubitemid 44862494)
11. Atiyeh BS, Costagliola M, Hayek SN. Keloid or hypertrophic scar: the controversy: review of the literature. Ann Plast Surg. 2005;54:676-680. (Pubitemid 40726841)
12. Mutalik S. Treatment of keloids and hypertrophic scars. Indian J Dermatol Venereol Leprol. 2005;71:3-8. (Pubitemid 40348224)
13. Berman B, Villa AM, Ramirez CC. Novel opportunities in the treatment and prevention of scarring. J Cutan Med Surg. 2004;8 (Suppl):32-36. (Pubitemid 40685111)
14. Berman B, Viera MH, Amini S, et al. Prevention and management of hypertrophic scars and keloids after burns in children. J Craniofac Surg. Accepted August 2007.
15. Duncan MR, Berman B. Differential regulation of collagen, glycosaminoglycan, fibronectin, and collagenase activity production in cultured human adult dermal fibroblasts by interleukin 1-alpha and beta and tumor necrosis factor-alpha and beta. J Invest Dermatol. 1989;92:699-706. (Pubitemid 19143619)
16. Papp KA, Keystone EC, Shear NH. Mechanism of action, pharmacokinetics, and drug interactions of etanercept in dermatology. J Cutan Med Surg. 2007;11 (Suppl):S3-S13.
17. Chou DH, Lee W, McCulloch CA. TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis. J Immunol. 1996;156:4354-4362. (Pubitemid 26165834)
18. Dhillon S, Lyseng-Williamson KA, Scott LJ. Etanercept: a review of its use in the management of rheumatoid arthritis. Drugs. 2007;67: 1211-1241. (Pubitemid 46880983)
19. Asilian A, Darougheh A, Shariati F. New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. Dermatol Surg. 2006;32:907-915. (Pubitemid 44034368)
20. Manuskiatti W, Fitzpatrick RE. Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. Arch Dermatol. 2002;138:1149-1155. (Pubitemid 35025686)