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Volumn 68, Issue 16, 2008, Pages 2345-2356

Bivalirudin: In patients with acute coronary syndromes planned for urgent or early intervention

Author keywords

Acute coronary syndromes; Adis Drug Profiles; Bivalirudin, general

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; ENOXAPARIN; FIBRINOGEN RECEPTOR ANTAGONIST; FONDAPARINUX; HEMOGLOBIN; HEPARIN; HIRULOG; TICLOPIDINE; TROPONIN;

EID: 55049131196     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/0003495-200868160-00006     Document Type: Review
Times cited : (4)

References (40)
  • 1
    • 34547772153 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes
    • Jul;
    • Bassand JP, Hamm CW, Ardissino D, et al. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J 2007 Jul; 28 (13): 1598-660
    • (2007) Eur Heart J , vol.28 , Issue.13 , pp. 1598-1660
    • Bassand, J.P.1    Hamm, C.W.2    Ardissino, D.3
  • 2
    • 10644234807 scopus 로고    scopus 로고
    • Antiplatelet and antithrombin therapy for early management of acute coronary syndromes
    • Wiggins BS, Spinler S. Antiplatelet and antithrombin therapy for early management of acute coronary syndromes. J Pharmacy Practice 2004; 17 (5): 347-69
    • (2004) J Pharmacy Practice , vol.17 , Issue.5 , pp. 347-369
    • Wiggins, B.S.1    Spinler, S.2
  • 3
    • 55049095305 scopus 로고    scopus 로고
    • American Heart Association and American Stroke Association. Heart disease and stroke statistics: 2008 update at-a-glance [online]. Available from URL: http://www.americanheart.org/downloadable/heart/1200082005246HS_Stats%202008. final.pdf [Accessed 2008 Jun 3]
    • American Heart Association and American Stroke Association. Heart disease and stroke statistics: 2008 update at-a-glance [online]. Available from URL: http://www.americanheart.org/downloadable/heart/1200082005246HS_Stats%202008. final.pdf [Accessed 2008 Jun 3]
  • 4
    • 34249026356 scopus 로고    scopus 로고
    • Evidence-based medical therapy of patients with acute coronary syndromes
    • Ramanath VS, Eagle KA. Evidence-based medical therapy of patients with acute coronary syndromes. Am J Cardiovasc Drugs 2007; 7 (2): 95-116
    • (2007) Am J Cardiovasc Drugs , vol.7 , Issue.2 , pp. 95-116
    • Ramanath, V.S.1    Eagle, K.A.2
  • 5
    • 20444497400 scopus 로고    scopus 로고
    • Routine vs selective invasive strategies in patients with acute coronary syndromes: A collaborative meta-analysis of randomized trials
    • Jun 15;
    • Mehta SR, Cannon CP, Fox KAA, et al. Routine vs selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials. JAMA 2005 Jun 15; 293 (23): 2908-17
    • (2005) JAMA , vol.293 , Issue.23 , pp. 2908-2917
    • Mehta, S.R.1    Cannon, C.P.2    Fox, K.A.A.3
  • 6
    • 85124050907 scopus 로고    scopus 로고
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2007 Aug 14; 50 (7): e1-157
    • Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2007 Aug 14; 50 (7): e1-157
  • 7
    • 0142041382 scopus 로고    scopus 로고
    • Predictors of major bleeding in acute coronary syndromes: The Global Registry of Acute Coronary Events (GRACE)
    • Oct;
    • Moscucci M, Fox KA, Cannon CP, et al. Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 2003 Oct; 24 (20): 1815-23
    • (2003) Eur Heart J , vol.24 , Issue.20 , pp. 1815-1823
    • Moscucci, M.1    Fox, K.A.2    Cannon, C.P.3
  • 8
    • 4644350897 scopus 로고    scopus 로고
    • Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes
    • Oct 6;
    • Rao SV, Jollis JG, Harrington RA, et al. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. JAMA 2004 Oct 6; 292 (13): 1555-62
    • (2004) JAMA , vol.292 , Issue.13 , pp. 1555-1562
    • Rao, S.V.1    Jollis, J.G.2    Harrington, R.A.3
  • 9
    • 25844504265 scopus 로고    scopus 로고
    • Predictors and 1-year outcome of major bleeding in patients with non-ST-elevation acute coronary syndromes: Insights from the Canadian Acute Coronary Syndrome Registries
    • Oct;
    • Segev A, Strauss BH, Tan M, et al. Predictors and 1-year outcome of major bleeding in patients with non-ST-elevation acute coronary syndromes: insights from the Canadian Acute Coronary Syndrome Registries. Am Heart J 2005 Oct; 150 (4): 690-4
    • (2005) Am Heart J , vol.150 , Issue.4 , pp. 690-694
    • Segev, A.1    Strauss, B.H.2    Tan, M.3
  • 10
    • 2942630624 scopus 로고    scopus 로고
    • Bivalent direct thrombin inhibitors: Hirudin and bivalirudin
    • Mar;
    • Warkentin TE. Bivalent direct thrombin inhibitors: hirudin and bivalirudin. Best Pract Res Clin Haematol 2004 Mar; 17 (1): 105-25
    • (2004) Best Pract Res Clin Haematol , vol.17 , Issue.1 , pp. 105-125
    • Warkentin, T.E.1
  • 11
    • 0003443998 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 May 14
    • European Medicines Agency. Angiox: summary of product characteristics [online]. Available from URL: http://www.emea.europa.eu/humandocs/PDFs/EPAR/ angiox/H-562-PI-en.pdf [Accessed 2008 May 14]
    • Angiox: Summary of product characteristics
  • 12
    • 55049128412 scopus 로고    scopus 로고
    • and, US prescribing information [online, Available from URL:, Accessed 2008 Jun 20
    • US Food and Drug Administration. Angiomax®: US prescribing information [online]. Available from URL: http://www.fda.gov/cder/foi/label/ 2005/020873s011lbl.pdf [Accessed 2008 Jun 20]
    • Angiomax®
    • Food, U.S.1
  • 13
    • 24344493000 scopus 로고    scopus 로고
    • Bivalirudin: A review of its use in patients undergoing percutaneous coronary intervention
    • Moen MD, Keating GM, Wellington K. Bivalirudin: a review of its use in patients undergoing percutaneous coronary intervention. Drugs 2005; 65 (13): 1869-91
    • (2005) Drugs , vol.65 , Issue.13 , pp. 1869-1891
    • Moen, M.D.1    Keating, G.M.2    Wellington, K.3
  • 14
    • 0036247598 scopus 로고    scopus 로고
    • Bivalirudin: A review of its potential place in the management of acute coronary syndromes
    • Carswell CI, Plosker GL. Bivalirudin: a review of its potential place in the management of acute coronary syndromes. Drugs 2002; 62 (5): 841-70
    • (2002) Drugs , vol.62 , Issue.5 , pp. 841-870
    • Carswell, C.I.1    Plosker, G.L.2
  • 15
    • 2542581490 scopus 로고    scopus 로고
    • Bivalirudin: An anticoagulant option for percutaneous coronary intervention
    • Mar;
    • Bates ER. Bivalirudin: an anticoagulant option for percutaneous coronary intervention. Expert Rev Cardiovasc Ther 2004 Mar; 2 (2): 153-62
    • (2004) Expert Rev Cardiovasc Ther , vol.2 , Issue.2 , pp. 153-162
    • Bates, E.R.1
  • 16
    • 33646758200 scopus 로고    scopus 로고
    • Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro
    • Jun;
    • Nielsen VG, Steenwyk BL, Gurley WQ, et al. Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro. J Heart Lung Transplant 2006 Jun; 25 (6): 653-63
    • (2006) J Heart Lung Transplant , vol.25 , Issue.6 , pp. 653-663
    • Nielsen, V.G.1    Steenwyk, B.L.2    Gurley, W.Q.3
  • 17
    • 34748921031 scopus 로고    scopus 로고
    • Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin
    • Oct;
    • Tanaka KA, Szlam F, Sun HY, et al. Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin. Anesth Analg 2007 Oct; 105 (4): 933-9
    • (2007) Anesth Analg , vol.105 , Issue.4 , pp. 933-939
    • Tanaka, K.A.1    Szlam, F.2    Sun, H.Y.3
  • 18
    • 0027392867 scopus 로고
    • Anticoagulant activity of Hirulog™, a direct thrombin inhibitor, in humans
    • Feb 1;
    • Fox I, Dawson A, Loynds P, et al. Anticoagulant activity of Hirulog™, a direct thrombin inhibitor, in humans. Thromb Haemost 1993 Feb 1; 69 (2): 157-63
    • (1993) Thromb Haemost , vol.69 , Issue.2 , pp. 157-163
    • Fox, I.1    Dawson, A.2    Loynds, P.3
  • 19
    • 11144357395 scopus 로고    scopus 로고
    • Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to reduced Clinical Events [REPLACE]-1 trial)
    • May 1;
    • Lincoff AM, Bittl JA, Kleiman NS, et al. Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to reduced Clinical Events [REPLACE]-1 trial). Am J Cardiol 2004 May 1; 93 (9): 1092-6
    • (2004) Am J Cardiol , vol.93 , Issue.9 , pp. 1092-1096
    • Lincoff, A.M.1    Bittl, J.A.2    Kleiman, N.S.3
  • 20
    • 0035983918 scopus 로고    scopus 로고
    • Bivalirudin pharmacokinetics and pharmacodynamics: Effect of renal function, dose, and gender
    • Jun;
    • Robson R, White H, Aylward P, et al. Bivalirudin pharmacokinetics and pharmacodynamics: effect of renal function, dose, and gender. Clin Pharmacol Ther 2002 Jun; 71 (6): 433-9
    • (2002) Clin Pharmacol Ther , vol.71 , Issue.6 , pp. 433-439
    • Robson, R.1    White, H.2    Aylward, P.3
  • 21
    • 0036238248 scopus 로고    scopus 로고
    • Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide
    • Apr;
    • Kleiman NS, Klem J, Fernandes LS, et al. Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide. Am Heart J 2002 Apr; 143 (4): 585-93
    • (2002) Am Heart J , vol.143 , Issue.4 , pp. 585-593
    • Kleiman, N.S.1    Klem, J.2    Fernandes, L.S.3
  • 22
    • 0027513462 scopus 로고
    • Anticoagulant effects of hirulog, a novel thrombin inhibitor, in patients with coronary artery disease
    • Apr 1;
    • Cannon CP, Maraganore JM, Loscalzo J, et al. Anticoagulant effects of hirulog, a novel thrombin inhibitor, in patients with coronary artery disease. Am J Cardiol 1993 Apr 1; 71 (10): 778-82
    • (1993) Am J Cardiol , vol.71 , Issue.10 , pp. 778-782
    • Cannon, C.P.1    Maraganore, J.M.2    Loscalzo, J.3
  • 23
    • 0027497137 scopus 로고
    • Initial experience with a direct antithrombin, hirulog, in unstable angina: Anticoagulant, antithrombotic, and clinical effects
    • Oct;
    • Lidón R-M, Théroux P, Juneau M, et al. Initial experience with a direct antithrombin, hirulog, in unstable angina: anticoagulant, antithrombotic, and clinical effects. Circulation 1993 Oct; 88 (4 Pt 1): 1495-501
    • (1993) Circulation , vol.88 , Issue.4 PART 1 , pp. 1495-1501
    • Lidón, R.-M.1    Théroux, P.2    Juneau, M.3
  • 24
    • 34447645830 scopus 로고    scopus 로고
    • Comparison of platelet function and morphology in patients undergoing percutaneous coronary intervention receiving bivalirudin versus unfractionated heparin versus clopidogrel pretreatment and bivalirudin
    • Aug 1;
    • Anand SX, Kim MC, Kamran M, et al. Comparison of platelet function and morphology in patients undergoing percutaneous coronary intervention receiving bivalirudin versus unfractionated heparin versus clopidogrel pretreatment and bivalirudin. Am J Cardiol 2007 Aug 1; 100 (3): 417-24
    • (2007) Am J Cardiol , vol.100 , Issue.3 , pp. 417-424
    • Anand, S.X.1    Kim, M.C.2    Kamran, M.3
  • 25
    • 0036624483 scopus 로고    scopus 로고
    • Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: Implications for coronary intervention
    • Jun;
    • Aggarwal A, Sobel BE, Schneider DJ. Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention. J Thromb Thrombolysis 2002 Jun; 13 (3): 161-5
    • (2002) J Thromb Thrombolysis , vol.13 , Issue.3 , pp. 161-165
    • Aggarwal, A.1    Sobel, B.E.2    Schneider, D.J.3
  • 26
    • 33745989916 scopus 로고    scopus 로고
    • Increased expression of platelet P-selectin and formation of platelet-leukocyte aggregates in blood from patients treated with unfractionated heparin plus eptifibatide compared with bivalirudin
    • Keating FK, Dauerman HL, Whitaker DA, et al. Increased expression of platelet P-selectin and formation of platelet-leukocyte aggregates in blood from patients treated with unfractionated heparin plus eptifibatide compared with bivalirudin. Thromb Res 2006; 118 (3): 361-9
    • (2006) Thromb Res , vol.118 , Issue.3 , pp. 361-369
    • Keating, F.K.1    Dauerman, H.L.2    Whitaker, D.A.3
  • 27
    • 33645552143 scopus 로고    scopus 로고
    • Anti-thrombotic effect of bivalirudin compared with eptifibatide and unfractionated heparin in diabetic patients: An ex vivo human study
    • Mar;
    • Lev EI, Patel R, Karim A, et al. Anti-thrombotic effect of bivalirudin compared with eptifibatide and unfractionated heparin in diabetic patients: an ex vivo human study. Thromb Haemost 2006 Mar; 95 (3): 441-6
    • (2006) Thromb Haemost , vol.95 , Issue.3 , pp. 441-446
    • Lev, E.I.1    Patel, R.2    Karim, A.3
  • 28
    • 28944444765 scopus 로고    scopus 로고
    • The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention
    • Sep 1;
    • Keating FK, Dauerman HL, Whitaker DA, et al. The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention. Coron Artery Dis 2005 Sep 1; 16 (6): 401-5
    • (2005) Coron Artery Dis , vol.16 , Issue.6 , pp. 401-405
    • Keating, F.K.1    Dauerman, H.L.2    Whitaker, D.A.3
  • 29
    • 2142641994 scopus 로고    scopus 로고
    • Pharmacodynamics (PD) and kinetics (PK) of bivalirudin (BIV) in renal failure (RF) and hemodialysis (HD) [abstract no. PIII-104]
    • Feb;
    • Irvin W, Sica D, Gehr T, et al. Pharmacodynamics (PD) and kinetics (PK) of bivalirudin (BIV) in renal failure (RF) and hemodialysis (HD) [abstract no. PIII-104]. Clin Pharmacol Ther 1999 Feb; 65 (2): 202
    • (1999) Clin Pharmacol Ther , vol.65 , Issue.2 , pp. 202
    • Irvin, W.1    Sica, D.2    Gehr, T.3
  • 30
    • 0029148676 scopus 로고    scopus 로고
    • Fuchs J, Cannon CP. Hirulog in the treatment of unstable angina: results of the Thrombin Inhibition in Myocardial Ischemia (TIMI) 7 trial. Circulation 1995 Aug 15; 92 (4): 727-33
    • Fuchs J, Cannon CP. Hirulog in the treatment of unstable angina: results of the Thrombin Inhibition in Myocardial Ischemia (TIMI) 7 trial. Circulation 1995 Aug 15; 92 (4): 727-33
  • 31
    • 0036482419 scopus 로고    scopus 로고
    • Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: Observations from the TIMI 8 trial
    • Feb;
    • Antman EM, McCabe CH, Braunwald E. Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: observations from the TIMI 8 trial. Am Heart J 2002 Feb; 143 (2): 229-34
    • (2002) Am Heart J , vol.143 , Issue.2 , pp. 229-234
    • Antman, E.M.1    McCabe, C.H.2    Braunwald, E.3
  • 32
    • 33751221316 scopus 로고    scopus 로고
    • Bivalirudin for patients with acute coronary syndromes
    • Nov 23;
    • Stone GW, McLaurin BT, Cox DA, et al. Bivalirudin for patients with acute coronary syndromes. N Engl J Med 2006 Nov 23; 355 (21): 2203-16
    • (2006) N Engl J Med , vol.355 , Issue.21 , pp. 2203-2216
    • Stone, G.W.1    McLaurin, B.T.2    Cox, D.A.3
  • 33
    • 36849087424 scopus 로고    scopus 로고
    • Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management: One-year results from the ACUITY trial
    • Dec 5;
    • Stone GW, Ware JH, Bertrand ME, et al. Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management: one-year results from the ACUITY trial. JAMA 2007 Dec 5; 298 (21): 2497-506
    • (2007) JAMA , vol.298 , Issue.21 , pp. 2497-2506
    • Stone, G.W.1    Ware, J.H.2    Bertrand, M.E.3
  • 34
    • 33947187284 scopus 로고    scopus 로고
    • Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary intervention: A subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial
    • Mar 17;
    • Stone GW, White HD, Ohman EM, et al. Bivalirudin in patients with acute coronary syndromes undergoing percutaneous coronary intervention: a subgroup analysis from the Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial. Lancet 2007 Mar 17; 369 (9565): 907-19
    • (2007) Lancet , vol.369 , Issue.9565 , pp. 907-919
    • Stone, G.W.1    White, H.D.2    Ohman, E.M.3
  • 35
    • 43049084442 scopus 로고    scopus 로고
    • Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: Results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
    • May 6;
    • White HD, Chew DP, Hoekstra JW, et al. Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. J Am Coll Cardiol 2008 May 6; 51 (18): 1734-41
    • (2008) J Am Coll Cardiol , vol.51 , Issue.18 , pp. 1734-1741
    • White, H.D.1    Chew, D.P.2    Hoekstra, J.W.3
  • 36
    • 43049160934 scopus 로고    scopus 로고
    • Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: A report from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
    • Apr 29;
    • Feit F, Manoukian SV, Ebrahimi R, et al. Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. J Am Coll Cardiol 2008 Apr 29; 51 (17): 1645-52
    • (2008) J Am Coll Cardiol , vol.51 , Issue.17 , pp. 1645-1652
    • Feit, F.1    Manoukian, S.V.2    Ebrahimi, R.3
  • 37
    • 50249086970 scopus 로고    scopus 로고
    • Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention: 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial
    • Sep 2;
    • White HD, Ohman M, Lincoff AM, et al. Safety and efficacy of bivalirudin with and without glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention: 1-year results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial. J Am Coll Cardiol 2008 Sep 2; 52 (10): 807-14
    • (2008) J Am Coll Cardiol , vol.52 , Issue.10 , pp. 807-814
    • White, H.D.1    Ohman, M.2    Lincoff, A.M.3
  • 38
    • 55049115271 scopus 로고    scopus 로고
    • European Medicines Agency. Angiox: scientific discussion [online]. Available from URL: http://www. emea.europa.eu/humandocs/PDFs/EPAR/angiox/ Angiox-AR-H-562-II-08.pdf [Accessed 2008 Jul 25]
    • European Medicines Agency. Angiox: scientific discussion [online]. Available from URL: http://www. emea.europa.eu/humandocs/PDFs/EPAR/angiox/ Angiox-AR-H-562-II-08.pdf [Accessed 2008 Jul 25]
  • 39
    • 13144257420 scopus 로고    scopus 로고
    • Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: Study design and rationale
    • Nov;
    • Stone GW, Bertrand M, Colombo A, et al. Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: study design and rationale. Am Heart J 2004 Nov; 148 (5): 764-75
    • (2004) Am Heart J , vol.148 , Issue.5 , pp. 764-775
    • Stone, G.W.1    Bertrand, M.2    Colombo, A.3
  • 40
    • 0034675059 scopus 로고    scopus 로고
    • The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making
    • Aug 16;
    • Antman EM, Cohen M, Bernink PJLM, et al. The TIMI risk score for unstable angina/non-ST elevation MI: a method for prognostication and therapeutic decision making. JAMA 2000 Aug 16; 284 (7): 835-42
    • (2000) JAMA , vol.284 , Issue.7 , pp. 835-842
    • Antman, E.M.1    Cohen, M.2    Bernink, P.J.L.M.3


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