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Volumn 95, Issue 3, 2006, Pages 441-446

Anti-thrombotic effect of bivalirudin compared with eptifibatide and unfractionated heparin in diabetic patients. An ex vivo human study

Author keywords

Antiplatelet drugs; Antithrombin; Diabetes metabolic disorders; Direct antithrombin agents; Platelet pharmacology

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; EPTIFIBATIDE; FIBRIN; FIBRINOGEN RECEPTOR; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRULOG; PADGEM PROTEIN;

EID: 33645552143     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH05-10-0700     Document Type: Article
Times cited : (19)

References (39)
  • 1
    • 0032406132 scopus 로고    scopus 로고
    • Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement
    • Elezi S, et al. Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement. J Am Coll Cardiol 1998; 32: 1866-73.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1866-1873
    • Elezi, S.1
  • 2
    • 0037106945 scopus 로고    scopus 로고
    • ESPRIT Investigators. Comparison of one-year outcomes following coronary artery stenting in diabetic versus non-diabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin therapy [ESPRIT] trial)
    • Labinaz M, et al; ESPRIT Investigators. Comparison of one-year outcomes following coronary artery stenting in diabetic versus non-diabetic patients (from the Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin therapy [ESPRIT] trial). Am J Cardiol. 2002; 90: 585-90.
    • (2002) Am J Cardiol. , vol.90 , pp. 585-590
    • Labinaz, M.1
  • 3
    • 0031670506 scopus 로고    scopus 로고
    • The influence of diabetes mellitus on acute and late clinical outcomes following coronary stent implantation
    • Abizaid A, et al. The influence of diabetes mellitus on acute and late clinical outcomes following coronary stent implantation. J Am Coll Cardiol 1998; 32: 584-9.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 584-589
    • Abizaid, A.1
  • 4
    • 0029027376 scopus 로고
    • The activated megakaryocyte-platelet system in vascular disease: Focus on diabetes
    • Tschoepe D. The activated megakaryocyte-platelet system in vascular disease: focus on diabetes. Semin Thromb Hemost 1995; 21: 152-60.
    • (1995) Semin Thromb Hemost , vol.21 , pp. 152-160
    • Tschoepe, D.1
  • 5
    • 4544248162 scopus 로고    scopus 로고
    • Relation of augmented platelet reactivity to the magnitude of distribution of atherosclerosis
    • Keating FK, et al. Relation of augmented platelet reactivity to the magnitude of distribution of atherosclerosis. Am J Cardiol 2004; 94: 725-8.
    • (2004) Am J Cardiol , vol.94 , pp. 725-728
    • Keating, F.K.1
  • 6
    • 15044361097 scopus 로고    scopus 로고
    • Aspirin response and failure in diabetic patients with cardiovascular disease
    • Yan Y, Phillips DR. Aspirin response and failure in diabetic patients with cardiovascular disease. Curr Opin Pharmacol 2005; 5: 190-7.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 190-197
    • Yan, Y.1    Phillips, D.R.2
  • 7
    • 13044304178 scopus 로고    scopus 로고
    • Blood-borne tissue factor: Another view of thrombosis
    • Giesen PL, et al. Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci USA 1999; 96: 2311-5.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2311-2315
    • Giesen, P.L.1
  • 8
    • 0037465510 scopus 로고    scopus 로고
    • Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity
    • Sambola A, et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity. Circulation 2003; 107: 973-7.
    • (2003) Circulation , vol.107 , pp. 973-977
    • Sambola, A.1
  • 9
    • 0034654627 scopus 로고    scopus 로고
    • Abciximab reduces mortality in diabetics following percutaneous intervention
    • Bhatt DL, et al. Abciximab reduces mortality in diabetics following percutaneous intervention. J Am Coll Cardiol 2000; 35: 922-8.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 922-928
    • Bhatt, D.L.1
  • 10
    • 0035808028 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa inhibitors reduce mortality in diabetic patients with non-ST-segment elevation acute coronary syndromes
    • Roffi M, et al. Platelet glycoprotein IIb/IIIa inhibitors reduce mortality in diabetic patients with non-ST-segment elevation acute coronary syndromes. Circulation 2001; 104: 2767-71.
    • (2001) Circulation , vol.104 , pp. 2767-2771
    • Roffi, M.1
  • 11
    • 0345451004 scopus 로고    scopus 로고
    • Diabetes mellitus, glycoprotein IIb/IIIa blockade, and heparin: Evidence of a complex interaction in a multicenter trial
    • EPILOG investigators
    • Kleiman NS, et al. Diabetes mellitus, glycoprotein IIb/IIIa blockade, and heparin: evidence of a complex interaction in a multicenter trial. EPILOG investigators. Circulation 1998; 97: 1912-20.
    • (1998) Circulation , vol.97 , pp. 1912-1920
    • Kleiman, N.S.1
  • 12
    • 3843060250 scopus 로고    scopus 로고
    • REPLACE-2 Investigators. Long-term efficacy of bivalirudin and provisional glycoprotein IIb/IIIa blockade vs heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary revascularization: REPLACE-2 randomized trial
    • Lincoff AM, et al; REPLACE-2 Investigators. Long-term efficacy of bivalirudin and provisional glycoprotein IIb/IIIa blockade vs heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary revascularization: REPLACE-2 randomized trial. JAMA 2004; 292: 696-703.
    • (2004) JAMA , vol.292 , pp. 696-703
    • Lincoff, A.M.1
  • 13
    • 20444503437 scopus 로고    scopus 로고
    • Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus: An analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (REPLACE)-2 trial
    • Gurm HS, et al. Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus: an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (REPLACE)-2 trial. J Am Coll Cardiol 2005; 45: 1932-8.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1932-1938
    • Gurm, H.S.1
  • 14
    • 0037453968 scopus 로고    scopus 로고
    • REPLACE-2 Investigators. Bivalirudin and provisional glycoprotein IIb/ IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial
    • Lincoff AM, et al; REPLACE-2 Investigators. Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial. JAMA 2003; 289: 853-63.
    • (2003) JAMA , vol.289 , pp. 853-863
    • Lincoff, A.M.1
  • 15
    • 0037126041 scopus 로고    scopus 로고
    • Randomized comparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: The COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, and Eptifibatide
    • Batchelor WB, et al. Randomized comparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, and Eptifibatide. Circulation 2002; 106: 1470-6.
    • (2002) Circulation , vol.106 , pp. 1470-1476
    • Batchelor, W.B.1
  • 16
    • 0035281821 scopus 로고    scopus 로고
    • Administration of abciximab to patients receiving tirofiban or eptifibatide: Effect on platelet function
    • Lev EI, et al. Administration of abciximab to patients receiving tirofiban or eptifibatide: effect on platelet function. J Am Coll Cardiol 2001; 37: 847-55.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 847-855
    • Lev, E.I.1
  • 17
    • 1542394536 scopus 로고    scopus 로고
    • Administration of eptifibatide to acute coronary syndrome patients receiving enoxaparin or unfractionated heparin: Effect on platelet function and thrombus formation
    • Lev EI, et al. Administration of eptifibatide to acute coronary syndrome patients receiving enoxaparin or unfractionated heparin: effect on platelet function and thrombus formation. J Am Coll Cardiol 2004; 43: 966-71.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 966-971
    • Lev, E.I.1
  • 18
    • 0031845763 scopus 로고    scopus 로고
    • Administration of abciximab during percutaneous coronary intervention reduces both ex vivo platelet thrombus formation and fibrin deposition: Implications for a potential anticoagulant effect of abciximab
    • Dangas G, et al. Administration of abciximab during percutaneous coronary intervention reduces both ex vivo platelet thrombus formation and fibrin deposition: implications for a potential anticoagulant effect of abciximab. Arterioscler Thromb Vasc Biol 1998; 18: 1342-9.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1342-1349
    • Dangas, G.1
  • 19
    • 0036238248 scopus 로고    scopus 로고
    • Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide
    • Kleiman NS, et al. Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/ IIIa antagonist eptifibatide. Am Heart J 2002; 143: 585-93.
    • (2002) Am Heart J , vol.143 , pp. 585-593
    • Kleiman, N.S.1
  • 20
    • 0036263519 scopus 로고    scopus 로고
    • The role of thrombin inhibition during percutaneous coronary intervention
    • Wittkowsky AK. The role of thrombin inhibition during percutaneous coronary intervention. Pharmacotherapy 2002; 22: 97S-104S.
    • (2002) Pharmacotherapy , vol.22
    • Wittkowsky, A.K.1
  • 21
    • 0036624483 scopus 로고    scopus 로고
    • Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: Implications for coronary intervention
    • Aggarwal A, et al. Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention. J Thromb Thrombolysis 2002; 13: 161-5.
    • (2002) J Thromb Thrombolysis , vol.13 , pp. 161-165
    • Aggarwal, A.1
  • 22
    • 28944444765 scopus 로고    scopus 로고
    • The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention
    • Keating FK, et al. The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention. Coron Artery Dis 2005; 16: 401-5.
    • (2005) Coron Artery Dis , vol.16 , pp. 401-405
    • Keating, F.K.1
  • 23
    • 28344441333 scopus 로고    scopus 로고
    • The P-selectin, tissue factor, coagulation triad
    • Polgar J, et al. The P-selectin, tissue factor, coagulation triad. J Thromb Haemost 2005; 3: 1590-6.
    • (2005) J Thromb Haemost , vol.3 , pp. 1590-1596
    • Polgar, J.1
  • 24
    • 12444303861 scopus 로고    scopus 로고
    • Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin
    • Falati S, et al. Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin. J Exp Med 2003; 197: 1585-98.
    • (2003) J Exp Med , vol.197 , pp. 1585-1598
    • Falati, S.1
  • 25
    • 23944509766 scopus 로고    scopus 로고
    • Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation
    • Del Conde I, et al. Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation. Blood 2005; 106: 1604-11.
    • (2005) Blood , vol.106 , pp. 1604-1611
    • Del Conde, I.1
  • 26
    • 0028240452 scopus 로고
    • Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture
    • Fernandez-Ortiz A, et al. Characterization of the relative thrombogenicity of atherosclerotic plaque components: Implications for consequences of plaque rupture. J Am Coll Cardiol 1994; 23: 1562-9.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1562-1569
    • Fernandez-Ortiz, A.1
  • 27
    • 0023522703 scopus 로고
    • Characterization of a tubular flow chamber for studying platelet interaction with biologic and prosthetic materials: Deposition of indium 111-labeled platelets on collagen, subendothelium, and expanded polytetrafluoroethylene
    • Badimon L, et al. Characterization of a tubular flow chamber for studying platelet interaction with biologic and prosthetic materials: Deposition of indium 111-labeled platelets on collagen, subendothelium, and expanded polytetrafluoroethylene. J Lab Clin Med 1987; 110: 706-18.
    • (1987) J Lab Clin Med , vol.110 , pp. 706-718
    • Badimon, L.1
  • 28
    • 0028100628 scopus 로고
    • Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis: Relative contribution of fibrin(ogen) and platelets
    • Mailhac A, et al. Effect of an eccentric severe stenosis on fibrin(ogen) deposition on severely damaged vessel wall in arterial thrombosis: Relative contribution of fibrin(ogen) and platelets. Circulation 1994; 90: 988-96.
    • (1994) Circulation , vol.90 , pp. 988-996
    • Mailhac, A.1
  • 29
    • 16944365813 scopus 로고    scopus 로고
    • Tissue factor modulates the thrombogenicity of atherosclerotic plaques
    • Toschi V, et al. Tissue factor modulates the thrombogenicity of atherosclerotic plaques. Circulation 1997; 95: 594-9.
    • (1997) Circulation , vol.95 , pp. 594-599
    • Toschi, V.1
  • 30
    • 0026341861 scopus 로고
    • Large platelets circulate in an activated state in diabetes mellitus
    • Tschoepe D, et al. Large platelets circulate in an activated state in diabetes mellitus. Semin Thromb Hemost 1991; 17: 433-8.
    • (1991) Semin Thromb Hemost , vol.17 , pp. 433-438
    • Tschoepe, D.1
  • 31
    • 1842687413 scopus 로고    scopus 로고
    • Augmentation of inhibitory effects of glycoprotein IIb-IIIa antagonists in patients with diabetes
    • Keating FK, et al. Augmentation of inhibitory effects of glycoprotein IIb-IIIa antagonists in patients with diabetes. Thromb Res 2004; 113: 27-34.
    • (2004) Thromb Res , vol.113 , pp. 27-34
    • Keating, F.K.1
  • 32
    • 0027379765 scopus 로고
    • The assembly of the prothrombinase complex on adherent platelets
    • Swords NA, Mann KG. The assembly of the prothrombinase complex on adherent platelets. Arterioscler Thromb 1993; 13: 1602-12.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1602-1612
    • Swords, N.A.1    Mann, K.G.2
  • 33
    • 0034656989 scopus 로고    scopus 로고
    • Antithrombotic effects of abciximab
    • Hayes R, et al. Antithrombotic effects of abciximab. Am J Cardiol 2000; 85: 1167-72.
    • (2000) Am J Cardiol , vol.85 , pp. 1167-1172
    • Hayes, R.1
  • 34
    • 0028962959 scopus 로고
    • Inhibition of platelet deposition by combined hirulog and aspirin in a rat carotid endarterectomy model
    • Hamelink JK, et al. Inhibition of platelet deposition by combined hirulog and aspirin in a rat carotid endarterectomy model. J Vase Surg 1995; 21: 492-8.
    • (1995) J Vase Surg , vol.21 , pp. 492-498
    • Hamelink, J.K.1
  • 35
    • 12144291702 scopus 로고    scopus 로고
    • Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions
    • Coppinger JA, et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 2004; 103: 2096-104.
    • (2004) Blood , vol.103 , pp. 52096-52104
    • Coppinger, J.A.1
  • 36
    • 0036588770 scopus 로고    scopus 로고
    • Direct thrombin inhibitors
    • Weitz JI, Crowther M. Direct thrombin inhibitors. Thromb Res 2002; 106:V275-84.
    • (2002) Thromb Res , vol.106
    • Weitz, J.I.1    Crowther, M.2
  • 37
    • 0043192675 scopus 로고    scopus 로고
    • Effect of glycoprotein IIb/IIIa antagonist abciximab on monocyte-platelet aggregates and tissue factor expression
    • Steiner S, et al. Effect of glycoprotein IIb/IIIa antagonist abciximab on monocyte-platelet aggregates and tissue factor expression. Arterioscler Thromb Vasc Biol 2003; 23: 1697-702.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1697-1702
    • Steiner, S.1
  • 38
    • 0242490979 scopus 로고    scopus 로고
    • Abciximab reduces monocyte tissue factor in carotid angioplasty and stenting
    • Kopp CW, et al. Abciximab reduces monocyte tissue factor in carotid angioplasty and stenting. Stroke 2003; 34: 2560-7.
    • (2003) Stroke , vol.34 , pp. 2560-2567
    • Kopp, C.W.1
  • 39
    • 0036847576 scopus 로고    scopus 로고
    • Antithrombotic effects of DX-9065a, a direct factor Xa inhibitor: A comparative study in humans versus low molecular weight heparin
    • Shimbo D, et al. Antithrombotic effects of DX-9065a, a direct factor Xa inhibitor: a comparative study in humans versus low molecular weight heparin. Thromb Haemost 2002; 88: 733-8.
    • (2002) Thromb Haemost , vol.88 , pp. 733-738
    • Shimbo, D.1


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