QSAR of antiproliferative activity of N-substituted 2-amino-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles in various human cancer cells

QSAR and Combinatorial Science

Volumn 27, Issue 5, 2008, Pages 607-617

  Matysiak, Joanna ^a  

^a UNIVERSITY OF LIFE SCIENCES IN LUBLIN   (Poland)

Author keywords

2 Amino 1,3,4 thiadiazoles; Antiproliferative activity; Lipophilicity; Quantum chemical descriptors

Indexed keywords

CANCER CELLS; CELL CULTURE; CELLS; COMPUTATIONAL CHEMISTRY; DISEASES; ELECTRONIC PROPERTIES; LINEAR REGRESSION; QUANTUM CHEMISTRY; SUBSTITUTION REACTIONS;

2-AMINO-1,3,4-THIADIAZOLE; ANTIPROLIFERATIVE ACTIVITIES; CANCER CELL LINES; HUMAN CANCER CELLS; IN-VITRO; LIPOPHILICITY; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; QUANTUM CHEMICAL DESCRIPTORS; RELATIONSHIP EQUATIONS; THIADIAZOLES;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

2 AMINO 5 (2,4 DIHYDROXYPHENYL) 1,3,4 THIADIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ACCURACY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ARTIFICIAL MEMBRANE; BLADDER CANCER; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; LUNG NON SMALL CELL CANCER; MULTIPLE LINEAR REGRESSION ANALYSIS; NEOPLASM; OVERPRESSURED LAYER CHROMATOGRAPHY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECTUM CARCINOMA;

EID: 54949126380     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200610157     Document Type: Article

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