Monitoring therapeutic anticoagulation with low molecular weight heparins: Is it useful or misleading?

Cardiovascular and Hematological Agents in Medicinal Chemistry

Volumn 6, Issue 4, 2008, Pages 282-286

  Hammerstingl, C ^a  

^a ST MARIEN HOSPITAL   (Germany)

Author keywords

Anti Xa testing; Anticoagulation; Low Molecular Weight Heparins; Myocardial ischemia; Oral anticoagulation (OAC); Pharmacokinetics; Unfractioned heparin (UFH); Vein thrombosis

Indexed keywords

2 [4 [(1 ACETIMIDOYL 3 PYRROLIDINYL)OXY]PHENYL] 3 (7 AMIDINO 2 NAPHTHYL)PROPIONIC ACID; ANTIVITAMIN K; BLOOD CLOTTING FACTOR 10A; CERTOPARIN; DALTEPARIN; ENOXAPARIN; FONDAPARINUX; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; PROTHROMBIN; REVIPARIN; TINZAPARIN;

ANTICOAGULANT THERAPY; ANTICOAGULATION; BLEEDING; BLOOD CLOTTING TIME; CHEMOPROPHYLAXIS; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; DEEP VEIN THROMBOSIS; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CHOICE; DRUG CLEARANCE; DRUG COST; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MEGADOSE; DRUG METABOLISM; DRUG MONITORING; DRUG SAFETY; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; LABORATORY TEST; LUNG EMBOLISM; PERIOPERATIVE PERIOD; REVIEW; SINGLE DRUG DOSE; THROMBIN TIME; THROMBOEMBOLISM; TREATMENT OUTCOME;

ANTICOAGULANTS; COST-BENEFIT ANALYSIS; FACTOR XA; HEPARIN, LOW-MOLECULAR-WEIGHT; HUMANS; THROMBIN; THROMBOPLASTIN; WHOLE BLOOD COAGULATION TIME;

EID: 54949113280     PISSN: 18715257     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152508785909492     Document Type: Review

References (35)

1. Salem, D.N.; Stein, P.D.; Al-Ahmad, A.; Bussey H.I.; Horstkotte, D.; Miller, N.; Pauker, S.G. Chest, 2004, 126, 457S.
2. Ansell, J.; Hirsh, J.; Poller, L.; Bussey, H.; Jacobson, A.; Hylek, E. Chest, 2004, 126, 204S.
3. Büller, H.R.; Agnelli, G.; Hull, R.D.; Hyers, T.M.; Prins, M.H.; Raskob, G.E. Chest, 2004, 126(3Suppl), 401S.
4. Dolovich, L.R.; Ginsberg, J.S.; Douketis, J.D.; Holbrook A.M.; Cheah G. Arch. Intern. Med., 2000, 160(2), 181.
5. Petersen, J.L.; Mahaffey, K.W.; Hasselblad, V.; Antman, E.M.; Cohen M.; Goodman, S.G.; Langer, A.; Blazing, M.A.; Le-Moigne-Amrani, A.; de Lemos, J.A.; Nessel, C.C.; Harrington, R.A.; Ferguson, J.J.; Braunwald, E.; Califf, R.M. JAMA, 2004, 292(1), 89.
6. Weitz, J.I. N. Engl. J. Med., 1997, 337(10), 688.
7. Hirsh, J.; Raschke, R. Chest, 2004, 126(3 Suppl.), 188S.
8. O'Donnell, M.J.; Kearon, C.; Johnson, J.; Robinson, M.; Zondag, M.; Turpie, I.; Turpie, A.G. Ann. Intern Med., 2007, 146, 184.
9. Douketis, J.D.; Woods, K.; Foster, G.A.; Crowther, M.A. Thromb. Haemost., 2005, 94(3), 528.
10. Alhenc-Gelas, M.; Jestin-Le Guernic, C.; Vitoux, J.E.; Kher, A.; Aiach, M.; Fiessinger, J.N. Thromb. Haemost., 1994, 71, 698.
11. Levine, M.N.; Planes, A.; Hirsh, J.; Goodyear, M.; Vochelle, N.; Gent; M. Thromb. Haemost., 1989, 62, 940.
12. Bara, L.; Leizorovicz, A.; Picolet, H; Samama, M. Thromb. Res., 1986, 56, 202.
13. Racine, E. Pharmaco-therapy, 2001, 21, 62.
14. Handeland, G.F.; Abildgaard, U.; Holm, H.A.; Arnesen, K.E. Eur. J. Clin. Pharmacol., 1990, 39, 107.
15. Danielsson, A.; Raub, E.; Lindahl, U.; Björk, I. J. Biol. Chem. 1986, 261, 15467.
16. Bara, L.; Samama, M.M. Acta Chir. Scand, 1988, 543, 65.
17. Bradbrook, I.D.; Magnani, H.N.; Moelker, H.C.; Morrison, P.J.; Robinson, J.; Rogers, H.J.; Spector, R.G.; Van Dinther, T.; Wijnand, H. Br. J. Clin. Pharmacol., 1987, 23, 667.
18. Kakkar, V.V.; Hoppenstead, D.A.; Fareed, J.; Kadziola, Z.; Scully, M.; Nakov, R.; Brddin, H.K. Blood, 2002, 99(6), 1965.
19. Brophy, D.F.; Martin, E.J.; Gehr, T.W.; Best, A.M.; Paul, K.; Carr, M.E., Jr. J. Thromb. Haemost., 2006, 4(2), 372.
20. Brophy, D.F.; Carr, M.E., Jr.; Martin, E.J.; Venitz J.; Gehr, T.W. J. Clin. Pharmacol., 2006, 46(8), 887.
21. Brophy, D.F.; Martin, E.J.; Gehr, T.W.; Carr, M.E., Jr. Am. J. Kidney Dis., 2004, 44(2), 270.
22. Marmur, J.D.; Anand, S.X.; Bagga, R.S.; Fareed, J.; Pan, C.M.; Sharma, S.K.; Richard, M.F. J. Am. Coll. Cardiol., 2003, 41, 394.
23. Cavusoglu, E.; Lakhani, M.; Marmur, J.D. J. Invasive Cardiol., 2005, 17(8), 416.
24. White, R.H.; Ginsberg, J.S. Br. J. Haematol., 2003, 121(1), 12.
25. Nenci, G.G. J. Thrombo. Haemost., 2003, 1(1), 12.
26. Nieuwenhuis, H.K.; Albada, J.; Banga, J.D.; Sixma, J.J. Blood, 1991, 78, 2337.
27. Becker, R.C.; Spencer, F.A.; Gibson, M.; Rush, J.E.; Sanderink, G.; Murphy, S.A.; Ball, S.P.; Antman, E.M. Am. Heart J., 2002, 143, 753.
28. Harenberg, J.; Stehle, G.; Blauth, M.; Huck, K.; Mall, K.; Heene, D.L. Semin. Thromb. Hemost., 1997, 23(1),83.
29. Bounameaux, H; DeMoerloose, P. J. Thromb. Haemost., 2004, 2, 551.
30. Harenberg, J. J. Thromb. Haemost., 2004, 2, 547.
31. Henry, T.D.; Satran, D.; Knox, LL.; Iacarella, CL.; Laxson, D.D.; Antman, E.M. Am. Heart., 2001, 142 (4), 590.
32. Harenberg, J.; Giese, C.; Hagedorn, A.; Traeger, I.; Fenyvesi, T. Semin. Thromb. Hemost., 2007, 33(5), 503.
33. Graff, J.; Picard-Willems, B.; Harder, S. Int. J. Clin. Pharmacol. Ther., 2007, 45(4), 237.
34. Gould, M.K.; Dembitzer, A.D.; Sanders, G.D.; Garber, A.M. Ann. Intern. Med., 1999, 130, 789.
35. Spyropoulos, A.C.; Frost, F.J.; Hurley, J.S.; Roberts, M. Chest, 2004, 125, 1642.