메뉴 건너뛰기




Volumn 121, Issue 1, 2003, Pages 12-20

Low-molecular-weight heparins: Are they all the same?

Author keywords

Comparison; Daltaparin; Enoxaparin; Low molecular weight heparin; Tinzaparin

Indexed keywords

DALTEPARIN; ENOXAPARIN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; TINZAPARIN; WARFARIN;

EID: 0037394009     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04196.x     Document Type: Review
Times cited : (79)

References (51)
  • 1
    • 0035023991 scopus 로고    scopus 로고
    • Plasma levels of total and free tissue factor pathway inhibitor (TFPI) as individual pharmacological parameters of various heparins
    • Alban, S. & Gastpar, R. (2001) Plasma levels of total and free tissue factor pathway inhibitor (TFPI) as individual pharmacological parameters of various heparins. Thrombosis and Haemostasis, 85, 824-829.
    • (2001) Thrombosis and Haemostasis , vol.85 , pp. 824-829
    • Alban, S.1    Gastpar, R.2
  • 2
    • 0029979442 scopus 로고    scopus 로고
    • Are the pharmacokinetic parameters of low molecular weight heparins predictive of their clinical efficacy?
    • Andrassy, K. & Eschenfelder, V. (1996) Are the pharmacokinetic parameters of low molecular weight heparins predictive of their clinical efficacy? Thrombosis Research, 81, s29-s38.
    • (1996) Thrombosis Research , vol.81
    • Andrassy, K.1    Eschenfelder, V.2
  • 4
    • 0032957278 scopus 로고    scopus 로고
    • Occurrence of thrombosis and haemorrhage, relationship with anti-Xa, anti-IIa activities, and D-dimer plasma levels in patients receiving a low-molecular-weight heparin, enoxaparin or tinzaparin, to prevent deep vein thrombosis after hip surgery
    • Bara, L., Planès, A. & Samama, M.M. (1999) Occurrence of thrombosis and haemorrhage, relationship with anti-Xa, anti-IIa activities, and D-dimer plasma levels in patients receiving a low-molecular-weight heparin, enoxaparin or tinzaparin, to prevent deep vein thrombosis after hip surgery. British Journal of Haematology, 104, 230-240.
    • (1999) British Journal of Haematology , vol.104 , pp. 230-240
    • Bara, L.1    Planès, A.2    Samama, M.M.3
  • 5
    • 0034091393 scopus 로고    scopus 로고
    • Dose-dependent release of endogenous tissue factor pathway inhibitor by different low molecular weight heparins
    • Bendz, B., Andersen, T.O. & Sandset, P.M. (2000) Dose-dependent release of endogenous tissue factor pathway inhibitor by different low molecular weight heparins. Blood Coagulation and Fibrinolysis, 11, 343-348.
    • (2000) Blood Coagulation and Fibrinolysis , vol.11 , pp. 343-348
    • Bendz, B.1    Andersen, T.O.2    Sandset, P.M.3
  • 6
    • 0032732653 scopus 로고    scopus 로고
    • Low molecular weight heparins: Differences and similarities in approved preparations in the United States
    • Bick, R.L. & Fareed, J. (1999) Low molecular weight heparins: differences and similarities in approved preparations in the United States. Clinical Applied Thrombosis and Hemostasis, 5, s63-s66.
    • (1999) Clinical Applied Thrombosis and Hemostasis , vol.5
    • Bick, R.L.1    Fareed, J.2
  • 7
    • 0027410948 scopus 로고
    • A comparison of the antithrombotic effects of heparin and of low-molecular-weight heparins with increasing antifactor Xa/antifactor IIa ratio in the rabbit
    • Carrie, D., Caranobe, C. & Boneu, B. (1993) A comparison of the antithrombotic effects of heparin and of low-molecular-weight heparins with increasing antifactor Xa/antifactor IIa ratio in the rabbit. British Journal of Haematology, 83, 622-626.
    • (1993) British Journal of Haematology , vol.83 , pp. 622-626
    • Carrie, D.1    Caranobe, C.2    Boneu, B.3
  • 8
    • 8544279582 scopus 로고    scopus 로고
    • A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease
    • Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group
    • Cohen, M., Demers, C., Gurfinkel, E.P., Turpie, A.G., Fromell, G.J., Goodman, S., Langer, A., Califf, R.M., Fox, K.A., Premmereur, J. & Bigonzi, F. (1997) A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group. New England Journal of Medicine, 337, 447-452.
    • (1997) New England Journal of Medicine , vol.337 , pp. 447-452
    • Cohen, M.1    Demers, C.2    Gurfinkel, E.P.3    Turpie, A.G.4    Fromell, G.J.5    Goodman, S.6    Langer, A.7    Califf, R.M.8    Fox, K.A.9    Premmereur, J.10    Bigonzi, F.11
  • 10
    • 0034707685 scopus 로고    scopus 로고
    • A meta-analysis comparing low-molecular-weight heparins with unfractionated heparin in the treatment of venous thromboembolism: Examining some unanswered questions regarding location of treatment, product type, and dosing frequency
    • Dolovich, L.R., Ginsberg, J.S., Douketis, J.D., Holbrook, A.M. & Cheah, G. (2000) A meta-analysis comparing low-molecular-weight heparins with unfractionated heparin in the treatment of venous thromboembolism: examining some unanswered questions regarding location of treatment, product type, and dosing frequency. Archives of Internal Medicine, 160, 181-188.
    • (2000) Archives of Internal Medicine , vol.160 , pp. 181-188
    • Dolovich, L.R.1    Ginsberg, J.S.2    Douketis, J.D.3    Holbrook, A.M.4    Cheah, G.5
  • 11
    • 0034600424 scopus 로고    scopus 로고
    • Unfractionated heparin and low-molecular-weight heparin in acute coronary syndrome without ST elevation: A meta-analysis
    • Eikelboom, J.W., Anand, S.S., Malmberg, K., Weitz, J.I., Ginsberg, J.S. & Yusuf, S. (2000) Unfractionated heparin and low-molecular-weight heparin in acute coronary syndrome without ST elevation: a meta-analysis. Lancet, 355, 1936-1942.
    • (2000) Lancet , vol.355 , pp. 1936-1942
    • Eikelboom, J.W.1    Anand, S.S.2    Malmberg, K.3    Weitz, J.I.4    Ginsberg, J.S.5    Yusuf, S.6
  • 12
    • 0035657406 scopus 로고    scopus 로고
    • Thromboprophylaxis following caesarean section. A comparison of the antithrombotic properties of three low molecular weight heparins: Dalteparin, enoxaparin and tinzaparin
    • Ellison, J., Thomson, A.J., Conkie, J.A., McCall, F., Walker, D. & Greer, A. (2001) Thromboprophylaxis following caesarean section. A comparison of the antithrombotic properties of three low molecular weight heparins: dalteparin, enoxaparin and tinzaparin. Thrombosis and Haemostasis, 86, 1374-1378.
    • (2001) Thrombosis and Haemostasis , vol.86 , pp. 1374-1378
    • Ellison, J.1    Thomson, A.J.2    Conkie, J.A.3    McCall, F.4    Walker, D.5    Greer, A.6
  • 13
    • 0028947113 scopus 로고
    • A comparative study of three low-molecular weight heparins (LMWH) and unfractionated heparin (UH) in healthy volunteers
    • Eriksson, B.I., Soderberg, K., Widlund, L., Wandeli, B., Tengborn, L. & Risberg, B. (1995) A comparative study of three low-molecular weight heparins (LMWH) and unfractionated heparin (UH) in healthy volunteers. Thrombosis and Haemostasis, 73, 398-401.
    • (1995) Thrombosis and Haemostasis , vol.73 , pp. 398-401
    • Eriksson, B.I.1    Soderberg, K.2    Widlund, L.3    Wandeli, B.4    Tengborn, L.5    Risberg, B.6
  • 14
    • 0036171348 scopus 로고    scopus 로고
    • A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in Orthopaedic surgery
    • Eriksson, B.I., Arfwidsson, A.C., Frison, L., Eriksson, U.G., Bylock, A., Kalebo, P., Fager, G. & Gustafsson, D. (2002) A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in Orthopaedic surgery. Thrombosis and Haemostasis, 87, 231-237.
    • (2002) Thrombosis and Haemostasis , vol.87 , pp. 231-237
    • Eriksson, B.I.1    Arfwidsson, A.C.2    Frison, L.3    Eriksson, U.G.4    Bylock, A.5    Kalebo, P.6    Fager, G.7    Gustafsson, D.8
  • 17
    • 0033612951 scopus 로고    scopus 로고
    • Invasive compared with non-invasive treatment in unstable coronary-artery disease; FRISC II prospective randomised multicentre study
    • Fragmin and Fast Revascularisation during Instability in Coronary Artery Disease Investigators (1999) Invasive compared with non-invasive treatment in unstable coronary-artery disease; FRISC II prospective randomised multicentre study. Lancet, 354, 708-715.
    • (1999) Lancet , vol.354 , pp. 708-715
  • 18
    • 9044243412 scopus 로고    scopus 로고
    • Low-molecular-weight heparin during instability in coronary artery disease
    • Fragmin during Instability in Coronary Artery Disease (FRISC) Study Group (1996) Low-molecular-weight heparin during instability in coronary artery disease. Lancet, 347, 561-568.
    • (1996) Lancet , vol.347 , pp. 561-568
  • 21
    • 0036098789 scopus 로고    scopus 로고
    • Tissue factor and tissue factor pathway inhibitor levels in unstable angina patients during short-term low-molecular-weight heparin administration
    • Gori, A.M., Fedi, S., Pepe, G., Falciani, M., Rogolino, A., Prisco, D., Gensini, G.F. & Abbate, R. (2002) Tissue factor and tissue factor pathway inhibitor levels in unstable angina patients during short-term low-molecular-weight heparin administration. British Journal of Haematology, 117, 693-698.
    • (2002) British Journal of Haematology , vol.117 , pp. 693-698
    • Gori, A.M.1    Fedi, S.2    Pepe, G.3    Falciani, M.4    Rogolino, A.5    Prisco, D.6    Gensini, G.F.7    Abbate, R.8
  • 22
    • 0032925807 scopus 로고    scopus 로고
    • Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A cost-effectiveness analysis
    • Gould, M.K., Dembitzer, A.D., Sanders, G.D. & Gather, A.M. (1999) Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A cost-effectiveness analysis. Annals of Internal Medicine, 130, 789-799.
    • (1999) Annals of Internal Medicine , vol.130 , pp. 789-799
    • Gould, M.K.1    Dembitzer, A.D.2    Sanders, G.D.3    Gather, A.M.4
  • 23
    • 0343627727 scopus 로고    scopus 로고
    • Thromoboprophylaxis in hip fracture surgery: A pilot study comparing danaparoid, enoxaparin and dalteparin
    • Group, T.S. (1999) Thromoboprophylaxis in hip fracture surgery: a pilot study comparing danaparoid, enoxaparin and dalteparin. Haemostasis, 29, 310-317.
    • (1999) Haemostasis , vol.29 , pp. 310-317
    • Group, T.S.1
  • 25
    • 0034667833 scopus 로고    scopus 로고
    • For the initial treatment of venous thromboembolism: Are all low-molecular-weight heparin compounds the same?
    • van der Heijden, J.F., Prins, M.H. & Büller, H.R. (2000) For the initial treatment of venous thromboembolism: are all low-molecular-weight heparin compounds the same? Thrombosis Research, 100, V121-V130.
    • (2000) Thrombosis Research , vol.100
    • Van Der Heijden, J.F.1    Prins, M.H.2    Büller, H.R.3
  • 27
    • 0036499045 scopus 로고    scopus 로고
    • Comparison of effects of dalteparin and enoxaparin on hemostatic parameters and von Willebrand factor in patients with unstable angina pectoris or non-ST-segment elevation acute myocardial infarction
    • Hodl, R., Huber, K., Kraxner, W., Nikfardjam, M., Schumacher, M., Fruhwald, F.M., Zorn, G., Wonisch, M. & Klein, W. (2002) Comparison of effects of dalteparin and enoxaparin on hemostatic parameters and von Willebrand factor in patients with unstable angina pectoris or non-ST-segment elevation acute myocardial infarction. American Journal of Cardiology, 89, 589-592.
    • (2002) American Journal of Cardiology , vol.89 , pp. 589-592
    • Hodl, R.1    Huber, K.2    Kraxner, W.3    Nikfardjam, M.4    Schumacher, M.5    Fruhwald, F.M.6    Zorn, G.7    Wonisch, M.8    Klein, W.9
  • 30
    • 0034042313 scopus 로고    scopus 로고
    • Low molecular weight heparin in acute coronary syndrome: Evidence for superior or equivalent efficacy compared with unfractionated heparin?
    • Kaul, S. & Shah, P.K. (2000) Low molecular weight heparin in acute coronary syndrome: evidence for superior or equivalent efficacy compared with unfractionated heparin? Journal of the American College of Cardiology, 35, 1699-1712.
    • (2000) Journal of the American College of Cardiology , vol.35 , pp. 1699-1712
    • Kaul, S.1    Shah, P.K.2
  • 31
    • 0030789174 scopus 로고    scopus 로고
    • Comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease. Fragmin in unstable coronary artery disease study (FRIC)
    • Klein, W., Buchwald, A., Hillis, S.E., Monrad, S., Sanz, G., Turpie, A.G., van der Meer, J., Olaisson, E., Undeland, S. & Ludwig, K. (1997) Comparison of low-molecular-weight heparin with unfractionated heparin acutely and with placebo for 6 weeks in the management of unstable coronary artery disease. Fragmin in unstable coronary artery disease study (FRIC). Circulation, 96, 61-68.
    • (1997) Circulation , vol.96 , pp. 61-68
    • Klein, W.1    Buchwald, A.2    Hillis, S.E.3    Monrad, S.4    Sanz, G.5    Turpie, A.G.6    Van Der Meer, J.7    Olaisson, E.8    Undeland, S.9    Ludwig, K.10
  • 32
    • 0035873988 scopus 로고    scopus 로고
    • Low molecular weight heparin and unfractionated heparin in thrombosis prophylaxis: Meta-analysis based on original patient data
    • Koch, A., Ziegler, S., Breitschwerdt, H. & Victor, N. (2001) Low molecular weight heparin and unfractionated heparin in thrombosis prophylaxis: meta-analysis based on original patient data. Thrombosis Research, 102, 295-309.
    • (2001) Thrombosis Research , vol.102 , pp. 295-309
    • Koch, A.1    Ziegler, S.2    Breitschwerdt, H.3    Victor, N.4
  • 34
    • 0027399508 scopus 로고
    • Factor Xa inhibition: Correlation between the plasma levels of anti-Xa activity and occurrence of thrombosis and haemorrhage
    • Leizorovicz, A., Bara, L., Samama, M.M. & Haugh, M.C. (1993) Factor Xa inhibition: correlation between the plasma levels of anti-Xa activity and occurrence of thrombosis and haemorrhage. Haemostasis, 23, 89-98.
    • (1993) Haemostasis , vol.23 , pp. 89-98
    • Leizorovicz, A.1    Bara, L.2    Samama, M.M.3    Haugh, M.C.4
  • 35
    • 0025988854 scopus 로고
    • The anti-coagulant effect in heparinized blood and plasma resulting from interactions with extrinsic pathway inhibitor
    • Lindahl, A.K., Abildgaard, U. & Staalesen, R. (1991) The anti-coagulant effect in heparinized blood and plasma resulting from interactions with extrinsic pathway inhibitor. Thrombosis Research, 64, 155-168.
    • (1991) Thrombosis Research , vol.64 , pp. 155-168
    • Lindahl, A.K.1    Abildgaard, U.2    Staalesen, R.3
  • 36
    • 0035380604 scopus 로고    scopus 로고
    • Low-molecular-weight heparins are essentially the same for treatment and prevention of venous thromboembolism
    • Lopez, L.M. (2001) Low-molecular-weight heparins are essentially the same for treatment and prevention of venous thromboembolism. Pharmacotherapy, 21, 56s-61s, 71s-72s.
    • (2001) Pharmacotherapy , vol.21
    • Lopez, L.M.1
  • 37
    • 0036014077 scopus 로고    scopus 로고
    • Therapeutic equivalency of low-molecular-weight heparins
    • McCart, G.M. & Kayser, S.R. (2002) Therapeutic equivalency of low-molecular-weight heparins. Annals of Pharmacotherapy, 36, 1042-1057.
    • (2002) Annals of Pharmacotherapy , vol.36 , pp. 1042-1057
    • McCart, G.M.1    Kayser, S.R.2
  • 38
    • 0033956811 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism in internal medicine with unfractionated or low-molecular-weight heparins: A meta-analysis of randomised clinical trials
    • Mismetti, P., Laporte-Simitsidis, S., Tardy, B., Cucherat, M., Buchmuller, A., Juillard-Delsart, D. & Decousus, H. (2000) Prevention of venous thromboembolism in internal medicine with unfractionated or low-molecular-weight heparins: a meta-analysis of randomised clinical trials. Thrombosis and Haemostasis, 81, 14-19.
    • (2000) Thrombosis and Haemostasis , vol.81 , pp. 14-19
    • Mismetti, P.1    Laporte-Simitsidis, S.2    Tardy, B.3    Cucherat, M.4    Buchmuller, A.5    Juillard-Delsart, D.6    Decousus, H.7
  • 39
    • 0035668874 scopus 로고    scopus 로고
    • Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery
    • Mismetti, P., Laporte, S., Darmon, J.Y., Buchmuller, A. & Decousus, H. (2001) Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery. British Journal of Surgery, 88, 913-930.
    • (2001) British Journal of Surgery , vol.88 , pp. 913-930
    • Mismetti, P.1    Laporte, S.2    Darmon, J.Y.3    Buchmuller, A.4    Decousus, H.5
  • 41
    • 0034325120 scopus 로고    scopus 로고
    • Anti-thrombotic efficacies of enoxaparin, dalteparin, and unfractionated heparin in venous thrombo-embolism
    • Morris, T.A., Marsh, J.J., Konopka, R., Pedersen, C.A. & Chiles, P.G. (2000) Anti-thrombotic efficacies of enoxaparin, dalteparin, and unfractionated heparin in venous thrombo-embolism. Thrombosis Research, 100, 185-194.
    • (2000) Thrombosis Research , vol.100 , pp. 185-194
    • Morris, T.A.1    Marsh, J.J.2    Konopka, R.3    Pedersen, C.A.4    Chiles, P.G.5
  • 43
    • 0031001452 scopus 로고    scopus 로고
    • Efficacy and safety of low molecular weight heparin, unfractionated heparin and warfarin for thrombo-embolism prophylaxis in orthopaedic surgery: A meta-analysis of randomised clinical trials
    • Palmer, A.J., Koppenhagen, K., Kirchhof, B., Weber, U. & Bergemann, R. (1997) Efficacy and safety of low molecular weight heparin, unfractionated heparin and warfarin for thrombo-embolism prophylaxis in orthopaedic surgery: a meta-analysis of randomised clinical trials. Haemostasis, 27, 75-84.
    • (1997) Haemostasis , vol.27 , pp. 75-84
    • Palmer, A.J.1    Koppenhagen, K.2    Kirchhof, B.3    Weber, U.4    Bergemann, R.5
  • 44
    • 0032892273 scopus 로고    scopus 로고
    • Prevention of deep vein thrombosis after hip replacement: Comparison between two low-molecular heparins, tinzaparin and enoxaparin
    • Planès, A., Samama, M.M., Lensing, A.W., Büller, H.R., Barre, J., Vochelle, N. & Beau, B. (1999) Prevention of deep vein thrombosis after hip replacement: comparison between two low-molecular heparins, tinzaparin and enoxaparin. Thrombosis and Haemostasis, 81, 22-25.
    • (1999) Thrombosis and Haemostasis , vol.81 , pp. 22-25
    • Planès, A.1    Samama, M.M.2    Lensing, A.W.3    Büller, H.R.4    Barre, J.5    Vochelle, N.6    Beau, B.7
  • 45
    • 0035380706 scopus 로고    scopus 로고
    • Differentiation of the low-molecular-weight heparins
    • discussion 71S-72S
    • Racine, E. (2001) Differentiation of the low-molecular-weight heparins. Pharmacotherapy, 21, 62S-70S; discussion 71S-72S.
    • (2001) Pharmacotherapy , vol.21
    • Racine, E.1
  • 47
    • 0030992622 scopus 로고    scopus 로고
    • Dose-ranging trial of enoxaparin for unstable angina: Results of TIMI 11A
    • The Thrombolysis in Myocardial Infarction (TIMI) 11A Trial Investigators (1997) Dose-ranging trial of enoxaparin for unstable angina: results of TIMI 11A. Journal of the American College of Cardiology, 29, 1474-1482.
    • (1997) Journal of the American College of Cardiology , vol.29 , pp. 1474-1482
  • 48
    • 0032904315 scopus 로고    scopus 로고
    • Hotline sessions at the 20th European Congress of Cardiology
    • Verheugt, F.W. (1999) Hotline sessions at the 20th European Congress of Cardiology, European Heart Journal, 20, 7-10.
    • (1999) European Heart Journal , vol.20 , pp. 7-10
    • Verheugt, F.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.