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Volumn 49, Issue 10, 2008, Pages 749-755

Reducing antimicrobial resistance through appropriate antibiotic usage in Singapore

Author keywords

Antibiotic surveillance; Antibiotic usage; Antimicrobial drug resistance; Antimicrobial stewardship; Clinical education; Pharmaceutical industry

Indexed keywords

ACINETOBACTER; ANTIBIOTIC RESISTANCE; DRUG INDUSTRY; ESCHERICHIA COLI; HEALTH SURVEY; HUMAN; INFECTION CONTROL; KLEBSIELLA; MEDICAL RESEARCH; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PRESCRIPTION; PUBLIC HEALTH; REVIEW; SINGAPORE; WORLD HEALTH ORGANIZATION;

EID: 54949086715     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (29)

References (38)
  • 1
    • 34748856687 scopus 로고    scopus 로고
    • BMJ readers choose the "sanitary revolution" as greatest medical advance since 1840
    • Ferriman A. BMJ readers choose the "sanitary revolution" as greatest medical advance since 1840. BMJ 2007; 334:111.
    • (2007) BMJ , vol.334 , pp. 111
    • Ferriman, A.1
  • 3
    • 10444287383 scopus 로고    scopus 로고
    • Infectious Diseases Society of America, a public health crisis brews. July, Available at:, Accessed July 5, 2008
    • Infectious Diseases Society of America. Bad bugs, no drugs: as antibiotic discovery stagnates... a public health crisis brews. July 2004. Available at: www.idsociety.org/badbugsnodrugs.html. Accessed July 5, 2008.
    • (2004) Bad bugs, no drugs: As antibiotic discovery stagnates
  • 4
    • 42549086795 scopus 로고    scopus 로고
    • The research agenda of the National Institute of Allergy and Infectious Diseases for antimicrobial resistance
    • Peters NK, Dixon DM, Holland SM, Fauci AS. The research agenda of the National Institute of Allergy and Infectious Diseases for antimicrobial resistance. J Infect Dis 2008; 197:1087-93.
    • (2008) J Infect Dis , vol.197 , pp. 1087-1093
    • Peters, N.K.1    Dixon, D.M.2    Holland, S.M.3    Fauci, A.S.4
  • 5
    • 84871309967 scopus 로고    scopus 로고
    • Available at:, Accessed August 1, 2008
    • World Health Organization. Antimicrobial Resistance. Available at: www.who.int/mediacentre/factsheets/fs194/en/. Accessed August 1, 2008.
    • Antimicrobial Resistance
  • 6
    • 33846116186 scopus 로고    scopus 로고
    • Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalization
    • Supenshine RH, Wright MO, Maragakis LL, et al. Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalization. Emerg Infect Dis 2007; 13:97-103.
    • (2007) Emerg Infect Dis , vol.13 , pp. 97-103
    • Supenshine, R.H.1    Wright, M.O.2    Maragakis, L.L.3
  • 7
    • 15944419940 scopus 로고    scopus 로고
    • The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: Mortality, length of stay, and hospital charges
    • Cosgrove SE, Qi Y, Kaye KS, et al. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 2005; 26:166-74.
    • (2005) Infect Control Hosp Epidemiol , vol.26 , pp. 166-174
    • Cosgrove, S.E.1    Qi, Y.2    Kaye, K.S.3
  • 9
    • 0028610312 scopus 로고
    • Multiple antibiotic resistance in Klebsiella spp. and other Enterobacteriaceae isolated in Singapore
    • Inglis TJ, Kumarasinghe G, Chow C, Liew HY. Multiple antibiotic resistance in Klebsiella spp. and other Enterobacteriaceae isolated in Singapore. Singapore Med J 1994; 35:602-4.
    • (1994) Singapore Med J , vol.35 , pp. 602-604
    • Inglis, T.J.1    Kumarasinghe, G.2    Chow, C.3    Liew, H.Y.4
  • 10
    • 0027018775 scopus 로고
    • Antimicrobial resistance: Patterns and trends in the National University Hospital, Singapore
    • Kumarasinghe G, Liew HY, Chow C. Antimicrobial resistance: patterns and trends in the National University Hospital, Singapore (1989-1991). Malaysian J Pathol 1992; 14:95-103.
    • (1992) Malaysian J Pathol , vol.14 , pp. 95-103
    • Kumarasinghe, G.1    Liew, H.Y.2    Chow, C.3
  • 11
    • 37149040172 scopus 로고    scopus 로고
    • Antimicrobial drug resistance in Singapore hospitals
    • Hsu LY, Tan TY, Jureen R, et al. Antimicrobial drug resistance in Singapore hospitals. Emerg Infect Dis 2007; 13:1944-7.
    • (2007) Emerg Infect Dis , vol.13 , pp. 1944-1947
    • Hsu, L.Y.1    Tan, T.Y.2    Jureen, R.3
  • 12
    • 0029000628 scopus 로고
    • Antimicrobial resistance problem in a university hospital
    • Kumarasinghe G, Chow C, Koh BL, et al. Antimicrobial resistance problem in a university hospital. Pathology 1995; 27:67-70.
    • (1995) Pathology , vol.27 , pp. 67-70
    • Kumarasinghe, G.1    Chow, C.2    Koh, B.L.3
  • 13
    • 20444467276 scopus 로고    scopus 로고
    • Dissemination of multisusceptible methicillin-resistant Staphylococcus aureus in Singapore
    • Hsu LY, Koh TH, Singh K, et al. Dissemination of multisusceptible methicillin-resistant Staphylococcus aureus in Singapore. J Clin Microbiol 2005; 43:2923-5.
    • (2005) J Clin Microbiol , vol.43 , pp. 2923-2925
    • Hsu, L.Y.1    Koh, T.H.2    Singh, K.3
  • 14
    • 33644878926 scopus 로고    scopus 로고
    • Establishment of ST30 as the predominant clonal type among community-associated methicillin-resistant Staphylococcus aureus isolates in Singapore
    • Hsu LY, Koh YL, Chlebicka NL, et al. Establishment of ST30 as the predominant clonal type among community-associated methicillin-resistant Staphylococcus aureus isolates in Singapore. J Clin Microbiol 2006; 44:1090-3.
    • (2006) J Clin Microbiol , vol.44 , pp. 1090-1093
    • Hsu, L.Y.1    Koh, Y.L.2    Chlebicka, N.L.3
  • 15
    • 12344337545 scopus 로고    scopus 로고
    • Heterogeneous vancomycin-resistant Staphylococcus aureus (hetero-VISA) in Singapore
    • Sng LH, Koh TH, Wang GC, et al. Heterogeneous vancomycin-resistant Staphylococcus aureus (hetero-VISA) in Singapore. Int J Antimicrob Agents 2005; 25:177-9.
    • (2005) Int J Antimicrob Agents , vol.25 , pp. 177-179
    • Sng, L.H.1    Koh, T.H.2    Wang, G.C.3
  • 16
    • 40949098152 scopus 로고    scopus 로고
    • Control of a hospital-wide vancomycin-resistant enterococci outbreak
    • Kurup A, Chlebicki MP, Ling ML, et al. Control of a hospital-wide vancomycin-resistant enterococci outbreak. Am J Infect Control 2008; 36:206-11.
    • (2008) Am J Infect Control , vol.36 , pp. 206-211
    • Kurup, A.1    Chlebicki, M.P.2    Ling, M.L.3
  • 17
    • 54949147482 scopus 로고    scopus 로고
    • Prevalence and predictors of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) Gram-negative bacteria at hospital presentation in Singapore
    • Kuala Lumpur, Malaysia; June 19-22
    • Pada S, Lye DC, Krishnan P, et al. Prevalence and predictors of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) Gram-negative bacteria at hospital presentation in Singapore. 13th International Congress on Infectious Diseases, Kuala Lumpur, Malaysia; June 19-22, 2008.
    • (2008) 13th International Congress on Infectious Diseases
    • Pada, S.1    Lye, D.C.2    Krishnan, P.3
  • 18
    • 0003758794 scopus 로고    scopus 로고
    • Part I, Atlanta: Centers for Disease Control and Prevention, Available at:, Accessed July 8, 2008
    • Interagency Task Force on Antimicrobial Resistance. A public health action plan to combat antimicrobial resistance. Part I. Domestic issues. Atlanta: Centers for Disease Control and Prevention, 2001:1-43. Available at: www.cdc.gov/drugresistance/actionplan/index.htm. Accessed July 8, 2008.
    • (2001) A public health action plan to combat antimicrobial resistance. Domestic issues , pp. 1-43
  • 19
    • 0031225237 scopus 로고    scopus 로고
    • Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: Guidelines for the prevention of antimicrobial resistance in hospitals
    • Shlaes DM, Gerding DN, John JF Jr, et al. Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Clin Infect Dis 1997; 25:584-99.
    • (1997) Clin Infect Dis , vol.25 , pp. 584-599
    • Shlaes, D.M.1    Gerding, D.N.2    John Jr, J.F.3
  • 20
    • 33846153776 scopus 로고    scopus 로고
    • Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship
    • Dellit TH, Owens RC, McGowan JE Jr, et al. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 2007; 44:159-77.
    • (2007) Clin Infect Dis , vol.44 , pp. 159-177
    • Dellit, T.H.1    Owens, R.C.2    McGowan Jr, J.E.3
  • 21
    • 0037471542 scopus 로고    scopus 로고
    • Unnecessary use of antimicrobials in hospitalized patients: Current patterns of misuse with an emphasis on the antianaerobic spectrum of activity
    • Hecker MT, Aron DC, Patel NP, Lehmann MK, Donskey CJ. Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity. Arch Intern Med 2003; 163:972-8.
    • (2003) Arch Intern Med , vol.163 , pp. 972-978
    • Hecker, M.T.1    Aron, D.C.2    Patel, N.P.3    Lehmann, M.K.4    Donskey, C.J.5
  • 22
    • 0018078767 scopus 로고
    • A study of antimicrobial misuse in a university hospital
    • Maki DG, Schuna AA. A study of antimicrobial misuse in a university hospital. Am J Med Sci 1978; 275:271-82.
    • (1978) Am J Med Sci , vol.275 , pp. 271-282
    • Maki, D.G.1    Schuna, A.A.2
  • 23
    • 84866013772 scopus 로고    scopus 로고
    • A retrospective study evaluating the use of imipenem & meropenem in a tertiary referral hospital in Singapore
    • Apr 27-28
    • Quek CL. A retrospective study evaluating the use of imipenem & meropenem in a tertiary referral hospital in Singapore. SGH 16th Annual Scientific Meeting; 2007 Apr 27-28.
    • (2007) SGH 16th Annual Scientific Meeting
    • Quek, C.L.1
  • 24
    • 31344475123 scopus 로고    scopus 로고
    • Health industry practices that create conflicts of interest: A policy proposal for academic medical centers
    • Brennan TA, Rothman DJ, Blank L, et al. Health industry practices that create conflicts of interest: a policy proposal for academic medical centers. JAMA 2006; 295:429-33.
    • (2006) JAMA , vol.295 , pp. 429-433
    • Brennan, T.A.1    Rothman, D.J.2    Blank, L.3
  • 25
    • 35748955531 scopus 로고    scopus 로고
    • Doctors and drug companies - scrutinizing influential relationships
    • Campbell EG. Doctors and drug companies - scrutinizing influential relationships. N Eng J Med 2007; 357:1796-7.
    • (2007) N Eng J Med , vol.357 , pp. 1796-1797
    • Campbell, E.G.1
  • 26
    • 60749120503 scopus 로고    scopus 로고
    • Available at:, Accessed August 1, 2008
    • Pharmaceutical Research and Manufacturers of America. Code on Interactions with Healthcare Professionals. Available at: www.phrma.org/files/ PhRMA%20Marketing%20Code%202008.pdf. Accessed August 1, 2008.
    • Code on Interactions with Healthcare Professionals
  • 27
    • 78149403885 scopus 로고    scopus 로고
    • Singapore Association of Pharmaceutical Industries, Available at:, Accessed August 1, 2008
    • Singapore Association of Pharmaceutical Industries. SAPI Code of Marketing Practices. 2003. Available at: www.sapi.org.sg/mktg.htm. Accessed August 1, 2008.
    • (2003) SAPI Code of Marketing Practices
  • 28
    • 54949085984 scopus 로고    scopus 로고
    • Singapore Medical Council, Available at:, Accessed August 1, 2008
    • Singapore Medical Council. Ethical Codes and Ethical Guidelines. 1997. Available at: www.smc.gov.sg/html/1150880218803.html. Accessed August 1, 2008.
    • (1997) Ethical Codes and Ethical Guidelines
  • 29
    • 33644875731 scopus 로고    scopus 로고
    • Interventions to improve antibiotic prescribing practices for hospital inpatients
    • CD003543
    • Davey P, Brown E, Fenelon L, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst Rev 2005(4):CD003543.
    • (2005) Cochrane Database Syst Rev , Issue.4
    • Davey, P.1    Brown, E.2    Fenelon, L.3
  • 30
    • 27144465823 scopus 로고    scopus 로고
    • Antimicrobial stewardship programs in health care systems
    • MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev 2005; 18:638-56.
    • (2005) Clin Microbiol Rev , vol.18 , pp. 638-656
    • MacDougall, C.1    Polk, R.E.2
  • 31
    • 33646473562 scopus 로고    scopus 로고
    • Optimising antimicrobial prescription in hospitals by introducing an antimicrobial stewardship programme in Hong Kong: Consensus statement
    • Ho PL, Cheng JC, Ching PT, et al. Optimising antimicrobial prescription in hospitals by introducing an antimicrobial stewardship programme in Hong Kong: consensus statement. Hong Kong Med J 2006; 12:141-8.
    • (2006) Hong Kong Med J , vol.12 , pp. 141-148
    • Ho, P.L.1    Cheng, J.C.2    Ching, P.T.3
  • 32
    • 85184973867 scopus 로고    scopus 로고
    • Nathwani D, Davey P. Antibiotic prescribing - are there lessons for physicians? QJM 1999; 92-287-92.
    • Nathwani D, Davey P. Antibiotic prescribing - are there lessons for physicians? QJM 1999; 92-287-92.
  • 33
    • 0029944327 scopus 로고    scopus 로고
    • Implementing antibiotic practice guidelines through computer-assisted decision support: Clinical and financial outcomes
    • Pestotnik SL, Classen DC, Evans RS, Burke JP. Implementing antibiotic practice guidelines through computer-assisted decision support: Clinical and financial outcomes. Ann Intern Med 1996; 124:884-90.
    • (1996) Ann Intern Med , vol.124 , pp. 884-890
    • Pestotnik, S.L.1    Classen, D.C.2    Evans, R.S.3    Burke, J.P.4
  • 34
    • 0032556943 scopus 로고    scopus 로고
    • A computer-assisted management program for antibiotics and other anti-infective agents
    • Evans RS, Pestotnik SL, Classen DC, et al. A computer-assisted management program for antibiotics and other anti-infective agents. N Engl J Med 1998; 338:232-8.
    • (1998) N Engl J Med , vol.338 , pp. 232-238
    • Evans, R.S.1    Pestotnik, S.L.2    Classen, D.C.3
  • 35
    • 27744605282 scopus 로고    scopus 로고
    • Clinical decision support and appropriateness of antimicrobial prescribing: A randomised trial
    • Samore MH, Bateman K, Alder SC, et al. Clinical decision support and appropriateness of antimicrobial prescribing: A randomised trial. JAMA 2005; 294: 2305-14.
    • (2005) JAMA , vol.294 , pp. 2305-2314
    • Samore, M.H.1    Bateman, K.2    Alder, S.C.3
  • 37
    • 0035916949 scopus 로고    scopus 로고
    • Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: Background, specific aims, and methods
    • Gonzales R, Bartlett JG, Besser RE, et al. Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Ann Intern Med 2001; 134:479-86.
    • (2001) Ann Intern Med , vol.134 , pp. 479-486
    • Gonzales, R.1    Bartlett, J.G.2    Besser, R.E.3
  • 38


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.