Subcutaneous injection of Mycobacterium ulcerans causes necrosis, chronic inflammatory response and fibrosis in skeletal muscle

Microbes and Infection

Volumn 10, Issue 12-13, 2008, Pages 1236-1243

  Houngbédji, Mabèrou Germain ^a   Boissinot, Maurice ^a   Bergeron, G Michel ^a,b   Frenette, Jérôme ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Inflammatory response; Muscle damage; Mycobacterium ulcerans

Indexed keywords

CYTOKINE; GROWTH FACTOR; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CONTROLLED STUDY; MACROPHAGE; MALE; MAST CELL; MEMBRANE DAMAGE; MOUSE; MUSCLE NECROSIS; MUSCLE STIFFNESS; MYCOBACTERIUM ULCERANS; MYOFIBROSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

MUS; MYCOBACTERIUM ULCERANS;

EID: 54849430712     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2008.07.041     Document Type: Article

References (29)

1. Asiedu K., and Etuaful S. Socioeconomic implications of Buruli ulcer in Ghana: a three-year review. Am. J. Trop. Med. Hyg. 59 (1998) 1015-1022
2. Marsollier L., Deniaux E., Brodin P., Marot A., Wondje C.M., Saint-Andre J.P., Chauty A., Johnson C., Tekaia F., Yeramian E., Legras P., Carbonnelle B., Reysset G., Eyangoh S., Milon G., Cole S.T., and Aubry J. Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva. PLoS Med. 4 (2007) e64
3. van der Werf T.S., van der Graaf W.T., Tappero J.W., and Asiedu K. Mycobacterium ulcerans infection. Lancet. 354 (1999) 1013-1018
4. Guarner J., Bartlett J., Whitney E.A., Raghunathan P.L., Stienstra Y., Asamoa K., Etuaful S., Klutse E., Quarshie E., van der Werf T.S., van der Graaf W.T., King C.H., and Ashford D.A. Histopathologic features of Mycobacterium ulcerans infection. Emerg. Infect. Dis. 9 (2003) 651-656
5. Stienstra Y., van Roest M.H., van Wezel M.J., Wiersma I.C., Hospers I.C., Dijkstra P.U., Johnson R.C., Ampadu E.O., Gbovi J., Zinsou C., Etuaful S., Klutse E.Y., van der Graaf W.T., and van der Werf T.S. Factors associated with functional limitations and subsequent employment or schooling in Buruli ulcer patients. Trop. Med. Int. Health. 10 (2005) 1251-1257
6. Pahlevan A.A., Wright D.J., Andrews C., George K.M., Small P.L., and Foxwell B.M. The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kappa B function. J. Immunol. 163 (1999) 3928-3935
7. George K.M., Barker L.P., Welty D.M., and Small P.L. Partial purification and characterization of biological effects of a lipid toxin produced by Mycobacterium ulcerans. Infect. Immun. 66 (1998) 587-593
8. Coutanceau E., Marsollier L., Brosch R., Perret E., Goossens P., Tanguy M., Cole S.T., Small P.L., and Demangel C. Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin. Cell Microbiol. 7 (2005) 1187-1196
9. Kiszewski A.E., Becerril E., Aguilar L.D., Kader I.T., Myers W., Portaels F., and Hernandez Pando R. The local immune response in ulcerative lesions of Buruli disease. Clin. Exp. Immunol. 143 (2006) 445-451
10. Yeboah-Manu D., Peduzzi E., Mensah-Quainoo E., Asante-Poku A., Ofori-Adjei D., Pluschke G., and Daubenberger C.A. Systemic suppression of interferon-gamma responses in Buruli ulcer patients resolves after surgical excision of the lesions caused by the extracellular pathogen Mycobacterium ulcerans. J. Leukoc. Biol. 79 (2006) 1150-1156
11. Phillips R., Horsfield C., Mangan J., Laing K., Etuaful S., Awuah P., Nyarko K., Osei-Sarpong F., Butcher P., Lucas S., and Wansbrough-Jones M. Cytokine mRNA expression in Mycobacteriam ulcerans-infected human skin and correlation with local inflammatory response. Infect. Immun. 74 (2006) 2917-2924
12. Schipper H.S., Rutgers B., Huitema M.G., Etuaful S.N., Westenbrink B.D., Limburg P.C., Timens W., and van der Werf T.S. Systemic and local interferon-gamma production following Mycobacterium ulcerans infection. Clin. Exp. Immunol. 150 (2007) 451-459
13. Dega H., Bentoucha A., Robert J., Jarlier V., and Grosset J. Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice. Antimicrob. Agents Chemother. 46 (2002) 3193-3196
14. Shepard C.C., and McRae D.H. A method for counting acid-fast bacteria. Int. J. Lepr. Other Mycobact. Dis. 36 (1968) 78-82
15. Goto M., Nakanaga K., Aung T., Hamada T., Yamada N., Nomoto M., Kitajima S., Ishii N., Yonezawa S., and Saito H. Nerve damage in Mycobacterium ulcerans-infected mice: probable cause of painlessness in buruli ulcer. Am. J. Pathol. 168 (2006) 805-811
16. Frenette J., Chbinou N., Godbout C., Marsolais D., and Frenette P.S. Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285 (2003) R727-R732
17. Dussault A.-A., and Pouliot M. Rapid and simple comparison of messenger RNA levels using real-time PCR. Biol. Proc. 8 1 (2006) 1-10
18. Hamer P.W., McGeachie J.M., Davies M.J., and Grounds M.D. Evans Blue dye as an in vivo marker of myofibre damage: optimising parameters for detecting initial myofibre membrane permeability. J. Anat. 200 (2002) 69-79
19. Brooks S.V., and Faulkner J.A. Contractile properties of skeletal muscles from young, adult and aged mice. J. Physiol. 404 (1988) 71-82
20. Gordon J.R., Burd P.R., and Galli S.J. Mast cells as a source of multifunctional cytokines. Immunol. Today. 11 (1990) 458-464
21. Meneghin A., and Hogaboam C.M. Infectious disease, the innate immune response, and fibrosis. J. Clin. Invest. 117 (2007) 530-538
22. Chen G., and Quinn L.S. Partial characterization of skeletal myoblast mitogens in mouse crushed muscle extract. J. Cell Physiol. 153 (1992) 563-574
23. Robertson T.A., Maley M.A., Grounds M.D., and Papadimitriou J.M. The role of macrophages in skeletal muscle regeneration with particular reference to chemotaxis. Exp. Cell Res. 207 (1993) 321-331
24. Wynn T.A. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Invest. 117 (2007) 524-529
25. Fertin C., Nicolas J.F., Gillery P., Kalis B., Banchereau J., and Maquart F.X. Interleukin-4 stimulates collagen synthesis by normal and scleroderma fibroblasts in dermal equivalents. Cell Mol. Biol. 37 (1991) 823-829
26. Maeda N., Kanda F., Okuda S., Ishihara H., and Chihara K. Transforming growth factor-beta enhances connective tissue growth factor expression in L6 rat skeletal myotubes. Neuromusc. Disord. 15 (2005) 790-793
27. Li Y., Foster W., Deasy B.M., Chan Y., Prisk V., Tang Y., Cummins J., and Huard J. Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis. Am. J. Pathol. 164 (2004) 1007-1019
28. Desmouliere A., Guyot C., and Gabbiani G. The stroma reaction myofibroblast: a key player in the control of tumor cell behavior. Int. J. Dev. Biol. 48 (2004) 509-517
29. Alexakis C., Partridge T., and Bou-Gharios G. Implication of the satellite cell in dystrophic muscle fibrosis: a self-perpetuating mechanism of collagen overproduction, Am. J. Physiol. Cell Physiol. 293 (2007) C661-C669