Correlation Between Insulin Resistance and Intracranial Atherosclerosis in Patients With Ischemic Stroke Without Diabetes

Journal of Stroke and Cerebrovascular Diseases

Volumn 17, Issue 6, 2008, Pages 401-405

  Park, Hyun Young ^a   Kyeong Ho, ^a   Park, Do Sim ^a   Lee, Hak Seung ^a   Chang, Hyuk ^a   Kim, Yo Sik ^a   Cho, Kwang Ho ^a  

^a Wonkwang University School of Medicine   (South Korea)

Author keywords

Insulin resistance; intracranial atherosclerosis; ischemic stroke

Indexed keywords

ACUTE DISEASE; ADULT; AGED; ARTICLE; BRAIN ANGIOGRAPHY; BRAIN ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; FEMALE; HOMEOSTASIS; HUMAN; INSULIN RESISTANCE; MAGNETIC RESONANCE ANGIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; BRAIN ISCHEMIA; CEREBRAL ANGIOGRAPHY; CEREBRAL ARTERIES; COHORT STUDIES; FEMALE; GLUCOSE; HUMANS; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; INSULIN RESISTANCE; INTRACRANIAL ARTERIOSCLEROSIS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; STROKE;

EID: 54849426846     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2008.06.004     Document Type: Article

References (25)

1. Lee K.S., Bae H.J., and Kim H.S. Utilization of health care resources and costs of stroke patients: Patients' perspective. J Korean Neurol Assoc 22 (2004) 583-589
2. Bang O.Y. Intracranial atherosclerotic stroke: Specific focus on the metabolic syndrome and inflammation. Curr Atheroscler Rep 8 (2006) 330-336
3. Bang O.Y., Kim J.W., Lee J.H., et al. Association of the metabolic syndrome with intracranial atherosclerotic stroke. Neurology 65 (2005) 296-298
4. Reaven G.M. Role of insulin resistance in human disease (syndrome X): An expanded definition. Annu Rev Med 44 (1993) 121-131
5. Kim M.H., Kim M.K., Choi B.Y., et al. Prevalence of the metabolic syndrome and its association with cardiovascular diseases in Korea. J Korean Med Sci 19 (2004) 195-201
6. Ovbiagele B., Saver J.L., Lynn M.J., et al. WASID study group: Impact of metabolic syndrome on prognosis of symptomatic intracranial atherosclerosis. Neurology 66 (2006) 1344-1349
7. Reilly M.P., and Rader D.J. The metabolic syndrome: More than the sum of its parts?. Circulation 108 (2003) 1546-1551
8. Lee K.U. Oxidative stress markers in Korean subjects in insulin resistance syndrome. Diabetes Res Clin Pract 54 (2001) 29-33 (suppl)
9. Kernan W.N., Inzucch S.E., Viscoli C.M., et al. Insulin resistance and risk of stroke. Neurology 59 (2002) 809-815
10. Pyorala M., Miettinen H., Laakso M., et al. Hyperinsulinemia and the risk or stroke in healthy middle-aged men: The 22 year follow-up results of the Helsinki policemen study. Stroke 29 (1998) 1860-1866
11. Folsom A.R., Eckfeldt J.H., Weitzman S., et al. Atherosclerosis risk in communities (ARIC) study investigators: Relation of carotid artery wall thickness to diabetes mellitus, fasting glucose and insulin, body size, and physical activity. Stroke 25 (1994) 66-73
12. Mizuno T., Matsui H., Imamura A., et al. Insulin resistance increase circulating malondialdehyde-modified LDL and impairs endothelial function in healthy young men. Int J Cardiol 97 (2004) 455-461
13. Folsom A.R., Rasmussen M.L., Chambless L.E., et al. Atherosclerosis risk in communities (ARIC) study investigators: Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. Diabetes Care 22 (1999) 1077-1083
14. Yanase M., Takatsu F., Tagawa T., et al. Insulin resistance and fasting hyperinsulinemia are risk factors for new cardiovascular events in patients with prior coronary artery disease and normal glucose tolerance. Circ J 68 (2004) 47-52
15. Yun K.H., Jeong M.H., Kim K.H., et al. The effect of insulin resistance on prognosis of non-diabetic patients who underwent percutaneous coronary intervention. J Korean Med Sci 21 (2006) 212-216
16. Park H.Y., Chang H., Park S.W., et al. Clinical characteristics and risk factors of the ischemic stroke: Wonkwang stroke registry. J Wonkwang Med Sci 15 (1999) 161-168
17. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
18. DeFronzo R.A. Is insulin resistance atherogenic? Possible mechanisms. Atherosclerosis 7 (2006) 11-15 (suppl)
19. Rewers M., Zaccaro D., D'Agostino R., et al. Insulin resistance atherosclerosis study investigators: Insulin sensitivity, insulinemia, and coronary artery disease; the insulin resistance atherosclerosis study. Diabetes Care 27 (2004) 781-787
20. Howard G., O'Leary D.H., Zaccaro D., et al. Insulin sensitivity and atherosclerosis. Circulation 93 (1996) 1809-1817
21. DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: A method for quantifying insulin secretion and resistance. Am J Physiol 237 (1979) 214-223
22. Haffner S.M., Miettinen H., and Stern M.P. The homeostasis model in the San Antonio heart study. Diabetes Care 20 (1997) 1087-1092
23. De Vriese A.S., Verbeuren T.J., Van de Voorde J., et al. Endothelial dysfunction in diabetes. Br J Pharmacol 130 (2000) 960-974
24. Takahashi F., Hasebe N., Kawashima E., et al. Hyperinsulinemia is an independent predictor for complex atherosclerotic lesion of thoracic aorta in non-diabetic patients. Atherosclerosis 187 (2006) 336-342
25. DeFonzo R.A., and Ferrannini E. Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14 (1991) 173-194