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Volumn 94, Issue 4, 2008, Pages 523-530

Cellular mechanisms of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MAPK signaling in hepatocellular carcinoma

Author keywords

Hepatocyte growth factor; Metastasis; Mitogen activated protein kinase; Urokinase plasminogen activator

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UROKINASE;

EID: 54749156297     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160809400414     Document Type: Article
Times cited : (5)

References (23)
  • 1
    • 0032919122 scopus 로고
    • Increased level of serum hepatocyte growth factor/scatter factor in liver cancer is associated with tumor metastasis
    • Junbo H, Li Q, Zaide W, Yunde H: Increased level of serum hepatocyte growth factor/scatter factor in liver cancer is associated with tumor metastasis. In Vivo, 13: 177-180, 1995.
    • (1995) In Vivo , vol.13 , pp. 177-180
    • Junbo, H.1    Li, Q.2    Zaide, W.3    Yunde, H.4
  • 2
    • 0036006814 scopus 로고    scopus 로고
    • Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition
    • Maulik G, Shrikhande A, Kijima T, Ma PC, Morrison PT, Salgia R: Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev, 13: 41-59, 2002.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 41-59
    • Maulik, G.1    Shrikhande, A.2    Kijima, T.3    Ma, P.C.4    Morrison, P.T.5    Salgia, R.6
  • 3
    • 0035041119 scopus 로고    scopus 로고
    • Receptor tyrosine kinases as therapeutic targets: The model of the MET oncogene
    • Longati P, Comoglio PM, Bardelli A: Receptor tyrosine kinases as therapeutic targets: the model of the MET oncogene. Curr Drug Targets, 2: 41-55, 2001.
    • (2001) Curr Drug Targets , vol.2 , pp. 41-55
    • Longati, P.1    Comoglio, P.M.2    Bardelli, A.3
  • 4
    • 0033087688 scopus 로고    scopus 로고
    • Elevation of urokinase-type plasminogen activator and its receptor densities as new predictors of disease progression and prognosis in men with prostate cancer
    • Miyake H, Hara L, Yamanaka K, Arakawa S, Kamidono S: Elevation of urokinase-type plasminogen activator and its receptor densities as new predictors of disease progression and prognosis in men with prostate cancer. Int J Oncol, 14: 35-41, 1999.
    • (1999) Int J Oncol , vol.14 , pp. 35-41
    • Miyake, H.1    Hara, L.2    Yamanaka, K.3    Arakawa, S.4    Kamidono, S.5
  • 5
    • 0029065722 scopus 로고
    • Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer
    • Duggan C, Maguire T, McDermott E, O'Higgins N, Fennelly JJ, Duffy MJ: Urokinase plasminogen activator and urokinase plasminogen activator receptor in breast cancer. Int J Cancer, 61: 597-600, 1995.
    • (1995) Int J Cancer , vol.61 , pp. 597-600
    • Duggan, C.1    Maguire, T.2    McDermott, E.3    O'Higgins, N.4    Fennelly, J.J.5    Duffy, M.J.6
  • 6
    • 26844434326 scopus 로고    scopus 로고
    • Invasion-metastasis by hepatocyte growth factor/c-Met signaling concomitant with induction of urokinase plasminogen activator in human pancreatic cancer: Role as therapeutic target
    • Lee KH, Hyun MS, Kim JY: Invasion-metastasis by hepatocyte growth factor/c-Met signaling concomitant with induction of urokinase plasminogen activator in human pancreatic cancer: role as therapeutic target. Cancer Res Treat, 35: 207-212, 2003.
    • (2003) Cancer Res Treat , vol.35 , pp. 207-212
    • Lee, K.H.1    Hyun, M.S.2    Kim, J.Y.3
  • 7
    • 0029834684 scopus 로고    scopus 로고
    • Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis
    • Xing RH, Rabbani SA: Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis. Int J Cancer, 67: 423-429, 1996.
    • (1996) Int J Cancer , vol.67 , pp. 423-429
    • Xing, R.H.1    Rabbani, S.A.2
  • 9
    • 0033543653 scopus 로고    scopus 로고
    • Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2
    • Iwasaki S, Iguchi M, Watanabe K, Hoshino R, Tsujimoto M, Kohno M: Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2. J Biol Chem, 274: 26503-26510, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 26503-26510
    • Iwasaki, S.1    Iguchi, M.2    Watanabe, K.3    Hoshino, R.4    Tsujimoto, M.5    Kohno, M.6
  • 10
    • 1442280989 scopus 로고    scopus 로고
    • The role of Gi, Gs and Gq/11-protein linked MAPK signaling in the regulation of hepatocellular carcinoma growth
    • Washington, DC, Dissertation
    • Schmidt CM: The role of Gi, Gs and Gq/11-protein linked MAPK signaling in the regulation of hepatocellular carcinoma growth. UMI Publishers, Washington, DC, 1998 (Dissertation).
    • (1998) UMI Publishers
    • Schmidt, C.M.1
  • 12
    • 0033621749 scopus 로고    scopus 로고
    • Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells
    • Restuccia C, Angelucci A, Gravina GL, Villanova I, Teti A, Albini A, Bologna M: Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells. Int J Cancer, 85: 407-415, 2000.
    • (2000) Int J Cancer , vol.85 , pp. 407-415
    • Restuccia, C.1    Angelucci, A.2    Gravina, G.L.3    Villanova, I.4    Teti, A.5    Albini, A.6    Bologna, M.7
  • 13
    • 0030951358 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinoma
    • Ueki T, Fujimoto J, Suzuki T, Yamamoto H, Okamoto E: Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinoma. Hepatology, 25: 619-623, 1997.
    • (1997) Hepatology , vol.25 , pp. 619-623
    • Ueki, T.1    Fujimoto, J.2    Suzuki, T.3    Yamamoto, H.4    Okamoto, E.5
  • 15
    • 0032910168 scopus 로고    scopus 로고
    • Organization and regulation of mitogen-activated protein kinase signaling pathways
    • Garrington TP, Johnson GL: Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol, 11: 211-218. 1999.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 211-218
    • Garrington, T.P.1    Johnson, G.L.2
  • 16
    • 0034826208 scopus 로고    scopus 로고
    • Hepatocyte growth factor/ scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways
    • Delehedde M, Sergeant N, Lyon M, Rudland PS, Fernig DG: Hepatocyte growth factor/ scatter factor stimulates migration of rat mammary fibroblasts through both mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt pathways. Eur J Biochem, 269: 4423-4429, 2001.
    • (2001) Eur J Biochem , vol.269 , pp. 4423-4429
    • Delehedde, M.1    Sergeant, N.2    Lyon, M.3    Rudland, P.S.4    Fernig, D.G.5
  • 17
    • 22944486688 scopus 로고    scopus 로고
    • Saposin C stimulates growth and invasion, activates p42/44 and SAPK/JNK signaling pathways of MAPK and upregulates uPA/uPAR expression in prostate cancer and stromal cells
    • Koochekpour S, Sartor O, Hiraiwa M, Lee TJ, Rayford W, Remmel N, Sandhoff K, Minokadeh A, Patten DY: Saposin C stimulates growth and invasion, activates p42/44 and SAPK/JNK signaling pathways of MAPK and upregulates uPA/uPAR expression in prostate cancer and stromal cells. Asian J Androl, 7: 147-158, 2005.
    • (2005) Asian J Androl , vol.7 , pp. 147-158
    • Koochekpour, S.1    Sartor, O.2    Hiraiwa, M.3    Lee, T.J.4    Rayford, W.5    Remmel, N.6    Sandhoff, K.7    Minokadeh, A.8    Patten, D.Y.9
  • 18
    • 0028053831 scopus 로고
    • Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells
    • Matsumoto K, Nakamura T, Kramer RH: Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells. J Biol Chem, 69: 31807-31813, 1994.
    • (1994) J Biol Chem , vol.69 , pp. 31807-31813
    • Matsumoto, K.1    Nakamura, T.2    Kramer, R.H.3
  • 19
    • 0034677772 scopus 로고    scopus 로고
    • Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells
    • Lai JF, Kao SC, Jiang ST, Tang MJ, Chan PC ,Chen HC: Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells. J Biol Chem, 275: 7474-7480, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 7474-7480
    • Lai, J.F.1    Kao, S.C.2    Jiang, S.T.3    Tang, M.J.4    Chan, P.C.5    Chen, H.C.6
  • 20
    • 33644797585 scopus 로고    scopus 로고
    • Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines
    • Lee KH, Choi EY, Kim MK, Hyun MS, Jang BI, Kim TN, Kim SW, Song SK, Kim JH. Kim JR: Regulation of hepatocyte growth factor-mediated urokinase plasminogen activator secretion by MEK/ERK activation in human stomach cancer cell lines. Exp Molec Med, 38: 27-35, 2006.
    • (2006) Exp Molec Med , vol.38 , pp. 27-35
    • Lee, K.H.1    Choi, E.Y.2    Kim, M.K.3    Hyun, M.S.4    Jang, B.I.5    Kim, T.N.6    Kim, S.W.7    Song, S.K.8    Kim, J.H.9    Kim, J.R.10
  • 22
    • 0034817112 scopus 로고    scopus 로고
    • MEK/ERK-mediated proliferation is negatively regulated by P38 MAP kinase in the hman pancreatic cancer cell line, PANC-1
    • Xian ZD, Thomas EA: MEK/ERK-mediated proliferation is negatively regulated by P38 MAP kinase in the hman pancreatic cancer cell line, PANC-1. Biochem Biophy Res Commun, 282: 447-453, 2001.
    • (2001) Biochem Biophy Res Commun , vol.282 , pp. 447-453
    • Xian, Z.D.1    Thomas, E.A.2
  • 23
    • 0142093556 scopus 로고    scopus 로고
    • Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis
    • Lee KH, Hyun MS, Kim JY: Growth factor-dependent activation of the MAPK pathway in human pancreatic cancer: MEK/ERK and p38 MAP kinase interaction in uPA synthesis. Clin Exp Meta, 20: 499-505, 2003.
    • (2003) Clin Exp Meta , vol.20 , pp. 499-505
    • Lee, K.H.1    Hyun, M.S.2    Kim, J.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.