메뉴 건너뛰기




Volumn 68, Issue 18, 2008, Pages 7352-7361

Regulation of apoptosis and caspase-8 expression in neuroblastoma cells by isoforms of the IG20 gene

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; SMALL INTERFERING RNA;

EID: 54749133061     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-6311     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 0001803359 scopus 로고    scopus 로고
    • Neuroblastoma
    • Pizzo PA, Poplack DG, editors, 5th ed. Philadelphia: JB Lippincott;
    • Brodeur G, Mris JM. Neuroblastoma. In: Pizzo PA, Poplack DG, editors. Principles and practice of pediatric oncology. 5th ed. Philadelphia: JB Lippincott; 2006. p. 933-70.
    • (2006) Principles and practice of pediatric oncology , pp. 933-970
    • Brodeur, G.1    Mris, J.M.2
  • 3
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur GM. Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 2003;3:203-16.
    • (2003) Nat Rev Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 4
    • 0030498642 scopus 로고    scopus 로고
    • Chow VT, Lee SS. DENN, a novel human gene differentially expressed in normal and neoplastic cells. DNA Seq 1996;6:263-73.
    • Chow VT, Lee SS. DENN, a novel human gene differentially expressed in normal and neoplastic cells. DNA Seq 1996;6:263-73.
  • 5
    • 0032144409 scopus 로고    scopus 로고
    • The human DENN gene: Genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22
    • Chow VT, Lim KM, Lim D. The human DENN gene: genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22. Genome 1998;41:543-52.
    • (1998) Genome , vol.41 , pp. 543-552
    • Chow, V.T.1    Lim, K.M.2    Lim, D.3
  • 6
    • 0035861631 scopus 로고    scopus 로고
    • Contrasting effects of IG20and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor α-induced apoptosis and activation of caspase-8 and -3
    • Al-Zoubi AM, Efimova EV, Kaithamana S, et al. Contrasting effects of IG20and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor α-induced apoptosis and activation of caspase-8 and -3. J Biol Chem 2001;276:47202-11.
    • (2001) J Biol Chem , vol.276 , pp. 47202-47211
    • Al-Zoubi, A.M.1    Efimova, E.V.2    Kaithamana, S.3
  • 7
    • 0347951247 scopus 로고    scopus 로고
    • IG20, a MADD splice variant, increases cell susceptibility to g-irradiation and induces soluble mediators that suppress tumor cell growth
    • Efimova E, Martinez O, Lokshin A, Arima T, Prabhakar BS. IG20, a MADD splice variant, increases cell susceptibility to g-irradiation and induces soluble mediators that suppress tumor cell growth. Cancer Res 2003;63:8768-76.
    • (2003) Cancer Res , vol.63 , pp. 8768-8776
    • Efimova, E.1    Martinez, O.2    Lokshin, A.3    Arima, T.4    Prabhakar, B.S.5
  • 8
    • 1442327641 scopus 로고    scopus 로고
    • IG20, in contrast to DENN-SV (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs
    • Efimova EV, Al-Zoubi AM, Martinez O, et al. IG20, in contrast to DENN-SV (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs. Oncogene 2004;23:1076-87.
    • (2004) Oncogene , vol.23 , pp. 1076-1087
    • Efimova, E.V.1    Al-Zoubi, A.M.2    Martinez, O.3
  • 9
    • 4444274866 scopus 로고    scopus 로고
    • IG20(MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC
    • Ramaswamy M, Efimova EV, Martinez O, Mulherkar NU, Singh SP, Prabhakar BS. IG20(MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC. Oncogene 2004;23:6083-94.
    • (2004) Oncogene , vol.23 , pp. 6083-6094
    • Ramaswamy, M.1    Efimova, E.V.2    Martinez, O.3    Mulherkar, N.U.4    Singh, S.P.5    Prabhakar, B.S.6
  • 10
    • 33749825177 scopus 로고    scopus 로고
    • Mulherkar N, Ramaswamy M, Mordi DC, Prabhakar BS. MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival. Oncogene 2006;25:6252-61.
    • Mulherkar N, Ramaswamy M, Mordi DC, Prabhakar BS. MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival. Oncogene 2006;25:6252-61.
  • 11
    • 0037195135 scopus 로고    scopus 로고
    • A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses
    • Yamaguchi K, Tanaka M, Mizoguchi A, et al. A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc Natl Acad Sci U S A 2002;99:14536-41.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14536-14541
    • Yamaguchi, K.1    Tanaka, M.2    Mizoguchi, A.3
  • 12
    • 0034768921 scopus 로고    scopus 로고
    • Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction
    • Tanaka M, Miyoshi J, Ishizaki H, et al. Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. Mol Biol Cell 2001;12:1421-30.
    • (2001) Mol Biol Cell , vol.12 , pp. 1421-1430
    • Tanaka, M.1    Miyoshi, J.2    Ishizaki, H.3
  • 13
    • 1642570212 scopus 로고    scopus 로고
    • Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons
    • Del Villar K, Miller CA. Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons. Proc Natl Acad Sci U S A 2004;101:4210-5.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4210-4215
    • Del Villar, K.1    Miller, C.A.2
  • 14
    • 0030910313 scopus 로고    scopus 로고
    • Schievella AR, Chen JH, Graham JR, Lin LL. MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase. J Biol Chem 1997;272:12069-75.
    • Schievella AR, Chen JH, Graham JR, Lin LL. MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase. J Biol Chem 1997;272:12069-75.
  • 15
    • 0032478078 scopus 로고    scopus 로고
    • A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system
    • Zhang Y, Zhou L, Miller CA. A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system. Proc Natl Acad Sci U S A 1998;95:2586-91.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2586-2591
    • Zhang, Y.1    Zhou, L.2    Miller, C.A.3
  • 16
    • 34249673962 scopus 로고    scopus 로고
    • Mulherkar N, Prasad KV, Prabhakar BS. MADD/DENN splice variant of the IG20gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells. J Biol Chem 2007;282:11715-21.
    • Mulherkar N, Prasad KV, Prabhakar BS. MADD/DENN splice variant of the IG20gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells. J Biol Chem 2007;282:11715-21.
  • 17
    • 0034066405 scopus 로고    scopus 로고
    • Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
    • Teitz T, Wei T, Valentine MB, et al. Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med 2000;6:529-35.
    • (2000) Nat Med , vol.6 , pp. 529-535
    • Teitz, T.1    Wei, T.2    Valentine, M.B.3
  • 18
    • 84889271499 scopus 로고    scopus 로고
    • IFNg sensitizes for apoptosis by up-regulating caspase-8 expression through the Stat1 pathway
    • Fulda S, Debatin KM. IFNg sensitizes for apoptosis by up-regulating caspase-8 expression through the Stat1 pathway. Oncogene 2002;21:2295-308.
    • (2002) Oncogene , vol.21 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.M.2
  • 19
    • 0034662625 scopus 로고    scopus 로고
    • Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
    • Hopkins-Donaldson S, Bodmer JL, Bourloud KB, Brognara CB, Tschopp J, Gross N. Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Cancer Res 2000;60:4315-9.
    • (2000) Cancer Res , vol.60 , pp. 4315-4319
    • Hopkins-Donaldson, S.1    Bodmer, J.L.2    Bourloud, K.B.3    Brognara, C.B.4    Tschopp, J.5    Gross, N.6
  • 20
    • 0034886497 scopus 로고    scopus 로고
    • Aggressive childhood neuroblastomas do not express caspase-8: An important component of programmed cell death
    • Teitz T, Lahti JM, Kidd VJ. Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death. J Mol Med 2001;79:428-36.
    • (2001) J Mol Med , vol.79 , pp. 428-436
    • Teitz, T.1    Lahti, J.M.2    Kidd, V.J.3
  • 21
    • 30144434107 scopus 로고    scopus 로고
    • Potentiation of neuroblastoma metastasis by loss of caspase-8
    • Stupack DG, Teitz T, Potter MD, et al. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature 2006;439:95-9.
    • (2006) Nature , vol.439 , pp. 95-99
    • Stupack, D.G.1    Teitz, T.2    Potter, M.D.3
  • 22
    • 0242300205 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector
    • Lee MT, Coburn GA, McClure MO, Cullen BR. Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector. J Virol 2003;77:11964-72.
    • (2003) J Virol , vol.77 , pp. 11964-11972
    • Lee, M.T.1    Coburn, G.A.2    McClure, M.O.3    Cullen, B.R.4
  • 23
    • 33845398930 scopus 로고    scopus 로고
    • An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells
    • De Ambrosis A, Casciano I, Croce M, et al. An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells. Int J Cancer 2007;120:39-47.
    • (2007) Int J Cancer , vol.120 , pp. 39-47
    • De Ambrosis, A.1    Casciano, I.2    Croce, M.3
  • 24
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 25
    • 20444424942 scopus 로고    scopus 로고
    • Genome-wide screening for gene function using RNAi in mammalian cells
    • Cullen LM, Arndt GM. Genome-wide screening for gene function using RNAi in mammalian cells. Immunol Cell Biol 2005;83:217-23.
    • (2005) Immunol Cell Biol , vol.83 , pp. 217-223
    • Cullen, L.M.1    Arndt, G.M.2
  • 26
    • 0035855626 scopus 로고    scopus 로고
    • Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
    • Fulda S, Kufer MU, Meyer E, van Valen F, Dockhorn-Dworniczak B, Debatin KM. Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene 2001;20:5865-77.
    • (2001) Oncogene , vol.20 , pp. 5865-5877
    • Fulda, S.1    Kufer, M.U.2    Meyer, E.3    van Valen, F.4    Dockhorn-Dworniczak, B.5    Debatin, K.M.6
  • 27
    • 0036913167 scopus 로고    scopus 로고
    • Expression and methylation of CASP8 in neuroblastoma: Identification of a promoter region
    • Banelli B, Casciano I, Croce M, et al. Expression and methylation of CASP8 in neuroblastoma: identification of a promoter region. Nat Med 2002;8:1333-5.
    • (2002) Nat Med , vol.8 , pp. 1333-1335
    • Banelli, B.1    Casciano, I.2    Croce, M.3
  • 28
    • 0036499701 scopus 로고    scopus 로고
    • The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells
    • Coppola T, Perret-Menoud V, Gattesco S, et al. The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells. Biochem J 2002;362:273-9.
    • (2002) Biochem J , vol.362 , pp. 273-279
    • Coppola, T.1    Perret-Menoud, V.2    Gattesco, S.3
  • 29
    • 32344435364 scopus 로고    scopus 로고
    • Purification and properties of Rab3 GEP (DENN/MADD)
    • Sakisaka T, Takai Y. Purification and properties of Rab3 GEP (DENN/MADD). Methods Enzymol 2005;403:254-61.
    • (2005) Methods Enzymol , vol.403 , pp. 254-261
    • Sakisaka, T.1    Takai, Y.2
  • 30
    • 0031589004 scopus 로고    scopus 로고
    • Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro
    • Nagase T, Ishikawa K, Nakajima D, et al. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res 1997;4:141-50.
    • (1997) DNA Res , vol.4 , pp. 141-150
    • Nagase, T.1    Ishikawa, K.2    Nakajima, D.3
  • 31
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe BJ. Alternative splicing: new insights from global analyses. Cell 2006;126:37-47.
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 32
    • 33749054403 scopus 로고    scopus 로고
    • Splicing regulation in neurologic disease
    • Licatalosi DD, Darnell RB. Splicing regulation in neurologic disease. Neuron 2006;52:93-101.
    • (2006) Neuron , vol.52 , pp. 93-101
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 34
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003;114:181-90.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 36
    • 0037373901 scopus 로고    scopus 로고
    • Induction of caspase 8 by interferon g renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB
    • Yang X, Merchant MS, Romero ME, et al. Induction of caspase 8 by interferon g renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB. Cancer Res 2003;63:1122-9.
    • (2003) Cancer Res , vol.63 , pp. 1122-1129
    • Yang, X.1    Merchant, M.S.2    Romero, M.E.3
  • 37
    • 3843124352 scopus 로고    scopus 로고
    • Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP
    • Muhlethaler-Mottet A, Bourloud KB, Auderset K, Joseph JM, Gross N. Drug-mediated sensitization to TRAIL-induced apoptosis in caspase-8-complemented neuroblastoma cells proceeds via activation of intrinsic and extrinsic pathways and caspase-dependent cleavage of XIAP, Bcl-xL and RIP. Oncogene 2004;23:5415-25.
    • (2004) Oncogene , vol.23 , pp. 5415-5425
    • Muhlethaler-Mottet, A.1    Bourloud, K.B.2    Auderset, K.3    Joseph, J.M.4    Gross, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.