Characterization and gene expression analysis of novel matched primary and metastatic renal cell carcinoma cell lines

Oncology Reports

Volumn 20, Issue 3, 2008, Pages 501-509

  Ohno, Yoshio ^a   Izumi, Miki ^a   Tachibana, Masaaki ^a   Kawamura, Takeshi ^a   Yoshioka, Kunihiko ^a   Aoyagi, Teiichiro ^a   Ohori, Makoto ^a   Namiki, Kazunori ^a   Sakamoto, Noboru ^a   Nakagami, Yoshihiro ^a   Hatano, Tadashi ^a   Akimoto, Shingo ^a   Nishimura, Toshihide ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Adrenal metastasis; Cell line; DNA microarray; Renal cell carcinoma

Indexed keywords

BETA CATENIN; BETA1 CATENIN; CADHERIN; CADHERIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR; LAMININ RECEPTOR; LAMININ RECEPTOR 1; TENASCIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MESSENGER RNA; RNA; TUMOR MARKER;

ADULT; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CASE REPORT; CELL ADHESION; DNA MICROARRAY; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MALE; METASTASIS; METASTASIS POTENTIAL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ADRENAL TUMOR; GENETICS; KARYOTYPING; KIDNEY TUMOR; METABOLISM; MIDDLE AGED; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ADRENAL GLAND NEOPLASMS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KARYOTYPING; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL;

EID: 54549116785     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or_00000034     Document Type: Article

References (20)

1. Landis SH, Murray T, Bolden S and Wingo PA: Cancer statistics. CA Cancer J Clin 49: 8-31, 1999.
2. deKernion JB and Belldegrun A: Renal tumors. In: Campbell's Urology. Walsh PC, Retik AB, Stamey TA, Vaughan ED (eds). WB Saunders Company, Philadelphia, pp1053-1093, 1999.
3. Maldazys JD and deKernion JB: Prognostic factors in metastatic renal carcinoma. J Urol 136: 376-379, 1986.
4. Murphy WM, Beckwith JB and Farrow GM: Tumors of the kidney. In: Atlas of Tumor Pathology. Rosai J (ed). Vol. 11, Armed Forces Institute of Pathology, Washington DC, pp1-180, 1994.
5. Bleumer I, Oosterwijk E, de Mulder P and Mulders PF: Immunotherapy for renal cell carcinoma. Eur Urol 44: 65-75, 2003.
6. Rini B and Small EJ: Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma. J Clin Oncol 23: 1028-1043, 2005.
7. Nakamura H, Saji H, Ogata A, et al: cDNA microarray analysis of gene expression in pathologic stage IA non-small cell lung carcinomas. Cancer 97: 2798-2805, 2003.
8. Yoshinaga K, Inoue H, Utsunomiya T, et al: N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma. Clin Cancer Res 10: 5702-5707, 2004.
9. Luu-The V, Paquet N, Calvo E and Cumps J: Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction. Biotechniques 38: 287-293, 2005.
10. Hamalainen H, Zhou H, Chou W, Hashizume H, Heller R and Lahesmaa R: Distinct gene expression profiles of human type 1 and type 2 T helper cells. Genome Biol 2: Research 0022.1-0022.11, 2001.
11. Tomisawa M, Tokunaga T, Oshika Y, et al: Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma. Eur J Cancer 35: 133-137, 1999.
12. Paul R, Nicknig U, Busch R, Ewing CM, Hartung R and Isaacs WB: Cadherin-6: a new prognostic marker for renal cell carcinoma. J Urol 171: 97-101, 2004.
13. Bretscher A, Reczek D and Berryman M: Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures. J Cell Sci 110: 3011-3018, 1997.
14. Ardini E, Tagliabue E, Magnifico A, Buto S, Castronovo V, Colnaghi MI and Menard S: Co-regulation and physical association of the 67-kDa monomeric laminin receptor and the alpha6beta4 integrin. J Biol Chem 272: 2342-2345, 1997.
15. Ardini E, Sporchia B, Pollegioni L, et al: Identification of a novel function for 67-kDa laminin receptor: increase in laminin degradation rate and release of motility fragments. Cancer Res 62: 1321-1325, 2002.
16. Givant-Horwitz V, Davidson B and Reich R: Laminin-induced signaling in tumor cells: the role of the M(r) 67,000 laminin receptor. Cancer Res 64: 3572-3579, 2004.
17. Kim MO, Yun SJ, Kim IS, Sohn S and Lee EH: Transforming growth factor-beta-inducible gene-h3 (beta(ig)-h3) promotes cell adhesion of human astrocytoma cells in vitro: implication of alpha6beta4 integrin. Neurosci Lett 336: 93-96, 2003.
18. Bae JS, Lee SH, Kim JE, et al: Beta ig-h3 supports keratinocyte adhesion, migration, and proliferation through alpha3beta1 integrin. Biochem Biophys Res Commun 294: 940-948, 2002.
19. Aitkenhead M, Wang SJ, Nakatsu MN, Mestas J, Heard C and Hughes CC: Identification of endothelial cell genes expressed in an in vitro model of angiogenesis: induction of ESM-1, (beta)ig-h3, and NrCAM. Microvasc Res 63: 159-171, 2002.
20. Schneider D, Kleeff J, Berberat PO, Zhu Z, Korc M, Friess H and Buchler MW: Induction and expression of betaig-h3 in pancreatic cancer cells. Biochim Biophys Acta 1588: 1-6, 2002.