An easy access to bioactive 13-hydroxylated and 11,13-dihydroxylated sesquiterpene lactones (SLs) through Michael addition of a nucleophilic hydroxyl group

Tetrahedron

Volumn 64, Issue 49, 2008, Pages 10996-11006

  Macías, Francisco A ^a   García Díaz, María D ^a   Massanet, Guillermo M ^a   Gómez Madero, José F ^a   Fronczek, Frank R ^b   Galindo, Juan C G ^a  

^a UNIVERSITY OF CÁDIZ   (Spain)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Enolates; HMPA; Michael addition; Peroxide intermediate; Sesquiterpene lactones; Solvent effect

Indexed keywords

11,13 DIHYDROXY SESQUITERPENE LACTONE; 13 HYDROXY SESQUITERPENE LACTONE; HEMPA; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; COLUMN CHROMATOGRAPHY; HYDROXYLATION; MICHAEL ADDITION; MOLECULAR MODEL; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLVENT EFFECT; STEREOCHEMISTRY; X RAY DIFFRACTION;

EID: 54549085359     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.09.024     Document Type: Article

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