메뉴 건너뛰기




Volumn 27, Issue 49, 2008, Pages 6356-6364

Evidence for Hox and E2A-PBX1 collaboration in mouse T-cell leukemia

Author keywords

Collaborator oncogenes; E2A PBX1; Hoxb4; T ALL

Indexed keywords

HOX PROTEIN; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR HOXB4; TRANSCRIPTION FACTOR PBX1; UNCLASSIFIED DRUG;

EID: 54549083348     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.233     Document Type: Article
Times cited : (20)

References (45)
  • 1
    • 27244440324 scopus 로고    scopus 로고
    • Molecular genetics of acute lymphoblastic leukemia
    • Armstrong SA, Look AT. (2005). Molecular genetics of acute lymphoblastic leukemia. J Clin Oncol 23: 6306-6315.
    • (2005) J Clin Oncol , vol.23 , pp. 6306-6315
    • Armstrong, S.A.1    Look, A.T.2
  • 2
    • 0031964860 scopus 로고    scopus 로고
    • Functional and regulatory interactions between Hox and extradenticle genes
    • Azpiazu N, Morata G. (1998). Functional and regulatory interactions between Hox and extradenticle genes. Genes Dev 12: 261-273.
    • (1998) Genes Dev , vol.12 , pp. 261-273
    • Azpiazu, N.1    Morata, G.2
  • 3
    • 0030752361 scopus 로고    scopus 로고
    • E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
    • Bain G, Engel I, Robanus Maandag EC, Te Riele HP, Voland JR, Sharp LL et al. (1997). E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol 17: 4782-4791.
    • (1997) Mol Cell Biol , vol.17 , pp. 4782-4791
    • Bain, G.1    Engel, I.2    Robanus Maandag, E.C.3    Te Riele, H.P.4    Voland, J.R.5    Sharp, L.L.6
  • 4
    • 0027992622 scopus 로고
    • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
    • Bain G, Maandag EC, Izon DJ, Amsen D, Kruisbeek AM, Weintraub BC et al. (1994). E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79: 885-892.
    • (1994) Cell , vol.79 , pp. 885-892
    • Bain, G.1    Maandag, E.C.2    Izon, D.J.3    Amsen, D.4    Kruisbeek, A.M.5    Weintraub, B.C.6
  • 5
    • 33744461803 scopus 로고    scopus 로고
    • HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation
    • Bergeron J, Clappier E, Cauwelier B, Dastugue N, Millien C, Delabesse E et al. (2006). HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation. Leukemia 20: 1184-1187.
    • (2006) Leukemia , vol.20 , pp. 1184-1187
    • Bergeron, J.1    Clappier, E.2    Cauwelier, B.3    Dastugue, N.4    Millien, C.5    Delabesse, E.6
  • 6
    • 12144252423 scopus 로고    scopus 로고
    • High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia
    • Bijl J, Sauvageau M, Thompson A, Sauvageau G. (2005). High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia. Genes Dev 19: 224-233.
    • (2005) Genes Dev , vol.19 , pp. 224-233
    • Bijl, J.1    Sauvageau, M.2    Thompson, A.3    Sauvageau, G.4
  • 7
    • 34548565789 scopus 로고    scopus 로고
    • Expression of a CALM-AF10 fusion gene leads to Hoxa cluster over-expression and acute leukemia in transgenic mice
    • Caudell D, Zhang Z, Chung YJ, Aplan PD. (2007). Expression of a CALM-AF10 fusion gene leads to Hoxa cluster over-expression and acute leukemia in transgenic mice. Cancer Res 67: 8022-8031.
    • (2007) Cancer Res , vol.67 , pp. 8022-8031
    • Caudell, D.1    Zhang, Z.2    Chung, Y.J.3    Aplan, P.D.4
  • 8
    • 33845544666 scopus 로고    scopus 로고
    • Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRbeta-HOXA rearrangement: A study of the Groupe Francophone de Cytogenetique Hematologique
    • Cauwelier B, Cave H, Gervais C, Lessard M, Barin C, Perot C et al. (2007). Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRbeta-HOXA rearrangement: a study of the Groupe Francophone de Cytogenetique Hematologique. Leukemia 21: 121-128.
    • (2007) Leukemia , vol.21 , pp. 121-128
    • Cauwelier, B.1    Cave, H.2    Gervais, C.3    Lessard, M.4    Barin, C.5    Perot, C.6
  • 9
    • 34247376989 scopus 로고    scopus 로고
    • Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells
    • Cellot S, Krosl J, Chagraoui J, Meloche S, Humphries RK, Sauvageau G. (2007). Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. Exp Hematol 35: 802-816.
    • (2007) Exp Hematol , vol.35 , pp. 802-816
    • Cellot, S.1    Krosl, J.2    Chagraoui, J.3    Meloche, S.4    Humphries, R.K.5    Sauvageau, G.6
  • 10
    • 0031031879 scopus 로고    scopus 로고
    • The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis
    • Chang CP, De Vivo I, Cleary ML. (1997). The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis. Mol Cell Biol 17: 81-88.
    • (1997) Mol Cell Biol , vol.17 , pp. 81-88
    • Chang, C.P.1    De Vivo, I.2    Cleary, M.L.3
  • 11
    • 0027184079 scopus 로고
    • Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice
    • Dedera DA, Waller EK, LeBrun DP, Sen-Majumdar A, Stevens ME, Barsh GS et al. (1993). Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice. Cell 74: 833-843.
    • (1993) Cell , vol.74 , pp. 833-843
    • Dedera, D.A.1    Waller, E.K.2    LeBrun, D.P.3    Sen-Majumdar, A.4    Stevens, M.E.5    Barsh, G.S.6
  • 12
    • 27644484043 scopus 로고    scopus 로고
    • CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes
    • Dik WA, Brahim W, Braun C, Asnafi V, Dastugue N, Bernard OA et al. (2005). CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia 19: 1948-1957.
    • (2005) Leukemia , vol.19 , pp. 1948-1957
    • Dik, W.A.1    Brahim, W.2    Braun, C.3    Asnafi, V.4    Dastugue, N.5    Bernard, O.A.6
  • 13
    • 0038240453 scopus 로고    scopus 로고
    • Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: Dominance of HOX dysregulation
    • Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ et al. (2003). Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 102: 262-268.
    • (2003) Blood , vol.102 , pp. 262-268
    • Ferrando, A.A.1    Armstrong, S.A.2    Neuberg, D.S.3    Sallan, S.E.4    Silverman, L.B.5    Korsmeyer, S.J.6
  • 14
    • 0021111388 scopus 로고
    • Molecular biology. Enhancers, chromosome position effects, and transgenic mice
    • Hogan B. (1983). Molecular biology. Enhancers, chromosome position effects, and transgenic mice. Nature 306: 313-314.
    • (1983) Nature , vol.306 , pp. 313-314
    • Hogan, B.1
  • 15
    • 0028115823 scopus 로고
    • Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen
    • Hough MR, Takei F, Humphries RK, Kay R. (1994). Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen. J Exp Med 179: 177-184.
    • (1994) J Exp Med , vol.179 , pp. 177-184
    • Hough, M.R.1    Takei, F.2    Humphries, R.K.3    Kay, R.4
  • 16
    • 0027434620 scopus 로고
    • E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice
    • Kamps MP, Baltimore D. (1993). E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice. Mol Cell Biol 13: 351-357.
    • (1993) Mol Cell Biol , vol.13 , pp. 351-357
    • Kamps, M.P.1    Baltimore, D.2
  • 17
    • 0025137176 scopus 로고
    • A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL
    • Kamps MP, Murre C, Sun XH, Baltimore D. (1990). A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell 60: 547-555.
    • (1990) Cell , vol.60 , pp. 547-555
    • Kamps, M.P.1    Murre, C.2    Sun, X.H.3    Baltimore, D.4
  • 18
    • 0032126633 scopus 로고    scopus 로고
    • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
    • Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. (1998). Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 17: 3714-3725.
    • (1998) EMBO J , vol.17 , pp. 3714-3725
    • Kroon, E.1    Krosl, J.2    Thorsteinsdottir, U.3    Baban, S.4    Buchberg, A.M.5    Sauvageau, G.6
  • 19
    • 0035253860 scopus 로고    scopus 로고
    • NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
    • Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. (2001). NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J 20: 350-361.
    • (2001) EMBO J , vol.20 , pp. 350-361
    • Kroon, E.1    Thorsteinsdottir, U.2    Mayotte, N.3    Nakamura, T.4    Sauvageau, G.5
  • 20
    • 0034718780 scopus 로고    scopus 로고
    • AP-1 complex is effector of Hox-induced cellular proliferation and transformation
    • Krosl J, Sauvageau G. (2000). AP-1 complex is effector of Hox-induced cellular proliferation and transformation. Oncogene 19: 5134-5141.
    • (2000) Oncogene , vol.19 , pp. 5134-5141
    • Krosl, J.1    Sauvageau, G.2
  • 21
    • 0344413639 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
    • Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G. (2003). In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med 9: 1428-1432.
    • (2003) Nat Med , vol.9 , pp. 1428-1432
    • Krosl, J.1    Austin, P.2    Beslu, N.3    Kroon, E.4    Humphries, R.K.5    Sauvageau, G.6
  • 22
    • 0028303736 scopus 로고
    • Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias
    • LeBrun DP, Cleary ML. (1994). Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias. Oncogene 9: 1641-1647.
    • (1994) Oncogene , vol.9 , pp. 1641-1647
    • LeBrun, D.P.1    Cleary, M.L.2
  • 23
    • 0030658039 scopus 로고    scopus 로고
    • Oncogenic transcription factors in the human acute leukemias
    • Look AT. (1997). Oncogenic transcription factors in the human acute leukemias. Science 278: 1059-1064.
    • (1997) Science , vol.278 , pp. 1059-1064
    • Look, A.T.1
  • 24
    • 0028231938 scopus 로고
    • Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation
    • Lu Q, Wright DD, Kamps MP. (1994). Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation. Mol Cell Biol 14: 3938-3948.
    • (1994) Mol Cell Biol , vol.14 , pp. 3938-3948
    • Lu, Q.1    Wright, D.D.2    Kamps, M.P.3
  • 25
    • 0029379593 scopus 로고
    • The specificity of homeotic gene function
    • Mann RS. (1995). The specificity of homeotic gene function. Bioessays 17: 855-863.
    • (1995) Bioessays , vol.17 , pp. 855-863
    • Mann, R.S.1
  • 26
    • 18344401779 scopus 로고    scopus 로고
    • In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster
    • Medina-Martinez O, Ramirez-Solis R. (2003). In vivo mutagenesis of the Hoxb8 hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster. Dev Biol 264: 77-90.
    • (2003) Dev Biol , vol.264 , pp. 77-90
    • Medina-Martinez, O.1    Ramirez-Solis, R.2
  • 27
    • 0025064238 scopus 로고
    • Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
    • Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD et al. (1990). Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor. Cell 60: 535-545.
    • (1990) Cell , vol.60 , pp. 535-545
    • Nourse, J.1    Mellentin, J.D.2    Galili, N.3    Wilkinson, J.4    Stanbridge, E.5    Smith, S.D.6
  • 28
    • 1342304050 scopus 로고    scopus 로고
    • Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1
    • Pineault N, Abramovich C, Ohta H, Humphries RK. (2004). Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol 24: 1907-1917.
    • (2004) Mol Cell Biol , vol.24 , pp. 1907-1917
    • Pineault, N.1    Abramovich, C.2    Ohta, H.3    Humphries, R.K.4
  • 29
    • 34248362004 scopus 로고    scopus 로고
    • B-cell development fails in the absence of the Pbx1 proto-oncogene
    • Sanyal M, Tung JW, Karsunky H, Zeng H, Selleri L, Weissman IL et al. (2007). B-cell development fails in the absence of the Pbx1 proto-oncogene. Blood 109: 4191-4199.
    • (2007) Blood , vol.109 , pp. 4191-4199
    • Sanyal, M.1    Tung, J.W.2    Karsunky, H.3    Zeng, H.4    Selleri, L.5    Weissman, I.L.6
  • 30
    • 0030891058 scopus 로고    scopus 로고
    • Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation
    • Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C et al. (1997). Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. Immunity 6: 13-22.
    • (1997) Immunity , vol.6 , pp. 13-22
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Hough, M.R.3    Hugo, P.4    Lawrence, H.J.5    Largman, C.6
  • 31
    • 79960971094 scopus 로고    scopus 로고
    • Evidence that chromosome instability and stem cell expansion cooperate to induce leukemia in mice
    • Sauvageau G, Thorsteinsdottir U, Mayotte N, Jerome LJ. (2001). Evidence that chromosome instability and stem cell expansion cooperate to induce leukemia in mice. Blood 98(Part: I): 836a.
    • (2001) Blood , vol.98 , Issue.PART I
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Mayotte, N.3    Jerome, L.J.4
  • 32
    • 22044457152 scopus 로고    scopus 로고
    • HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
    • Soulier J, Clappier E, Cayuela JM, Regnault A, Garcia-Peydro M, Dombret H et al. (2005). HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 106: 274-286.
    • (2005) Blood , vol.106 , pp. 274-286
    • Soulier, J.1    Clappier, E.2    Cayuela, J.M.3    Regnault, A.4    Garcia-Peydro, M.5    Dombret, H.6
  • 33
    • 20144363957 scopus 로고    scopus 로고
    • A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
    • Speleman F, Cauwelier B, Dastugue N, Cools J, Verhasselt B, Poppe B et al. (2005). A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias. Leukemia 19: 358-366.
    • (2005) Leukemia , vol.19 , pp. 358-366
    • Speleman, F.1    Cauwelier, B.2    Dastugue, N.3    Cools, J.4    Verhasselt, B.5    Poppe, B.6
  • 34
    • 33746852153 scopus 로고    scopus 로고
    • Transforming potential of the T-cell acute lymphoblastic leukemia-associated homeobox genes HOXA13, TLX1, and TLX3
    • Su X, Drabkin H, Clappier E, Morgado E, Busson M, Romana S et al. (2006). Transforming potential of the T-cell acute lymphoblastic leukemia-associated homeobox genes HOXA13, TLX1, and TLX3. Genes Chromosomes Cancer 45: 846-855.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 846-855
    • Su, X.1    Drabkin, H.2    Clappier, E.3    Morgado, E.4    Busson, M.5    Romana, S.6
  • 35
    • 0037082446 scopus 로고    scopus 로고
    • HOX-A10 regulates hematopoietic lineage commitment: Evidence for a monocyte-specific transcription factor
    • Taghon T, Stolz F, De Smedt M, Cnockaert M, Verhasselt B, Plum J et al. (2002). HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor. Blood 99: 1197-1204.
    • (2002) Blood , vol.99 , pp. 1197-1204
    • Taghon, T.1    Stolz, F.2    De Smedt, M.3    Cnockaert, M.4    Verhasselt, B.5    Plum, J.6
  • 36
    • 0038040548 scopus 로고    scopus 로고
    • Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: Implications for human T-cell development
    • Taghon T, Thys K, De Smedt M, Weerkamp F, Staal FJ, Plum J et al. (2003). Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: implications for human T-cell development. Leukemia 17: 1157-1163.
    • (2003) Leukemia , vol.17 , pp. 1157-1163
    • Taghon, T.1    Thys, K.2    De Smedt, M.3    Weerkamp, F.4    Staal, F.J.5    Plum, J.6
  • 37
    • 0037441599 scopus 로고    scopus 로고
    • Global down-regulation of HOX gene expression in PML-RARalpha + acute promyelocytic leukemia identified by small-array real-time PCR
    • Thompson A, Quinn MF, Grimwade D, O'Neill CM, Ahmed MR, Grimes S et al. (2003). Global down-regulation of HOX gene expression in PML-RARalpha + acute promyelocytic leukemia identified by small-array real-time PCR. Blood 101: 1558-1565.
    • (2003) Blood , vol.101 , pp. 1558-1565
    • Thompson, A.1    Quinn, M.F.2    Grimwade, D.3    O'Neill, C.M.4    Ahmed, M.R.5    Grimes, S.6
  • 38
    • 0032796188 scopus 로고    scopus 로고
    • The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells
    • Thorsteinsdottir U, Krosl J, Kroon E, Haman A, Hoang T, Sauvageau G. (1999). The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells. Mol Cell Biol 19: 6355-6366.
    • (1999) Mol Cell Biol , vol.19 , pp. 6355-6366
    • Thorsteinsdottir, U.1    Krosl, J.2    Kroon, E.3    Haman, A.4    Hoang, T.5    Sauvageau, G.6
  • 39
    • 0036090290 scopus 로고    scopus 로고
    • Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion
    • Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence HJ et al. (2002). Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood 99: 121-129.
    • (2002) Blood , vol.99 , pp. 121-129
    • Thorsteinsdottir, U.1    Mamo, A.2    Kroon, E.3    Jerome, L.4    Bijl, J.5    Lawrence, H.J.6
  • 40
    • 0031031880 scopus 로고    scopus 로고
    • Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia
    • Thorsteinsdottir U, Sauvageau G, Hough MR, Dragowska W, Lansdorp PM, Lawrence HJ et al. (1997). Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol 17: 495-505.
    • (1997) Mol Cell Biol , vol.17 , pp. 495-505
    • Thorsteinsdottir, U.1    Sauvageau, G.2    Hough, M.R.3    Dragowska, W.4    Lansdorp, P.M.5    Lawrence, H.J.6
  • 41
  • 42
    • 0029160039 scopus 로고
    • Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2
    • van Dijk MA, Peltenburg LT, Murre C. (1995). Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2. Mech Dev 52: 99-108.
    • (1995) Mech Dev , vol.52 , pp. 99-108
    • van Dijk, M.A.1    Peltenburg, L.T.2    Murre, C.3
  • 43
    • 0027176915 scopus 로고
    • Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia
    • van Dijk MA, Voorhoeve PM, Murre C. (1993). Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia. Proc Natl Acad Sci USA 90: 6061-6065.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6061-6065
    • van Dijk, M.A.1    Voorhoeve, P.M.2    Murre, C.3
  • 44
    • 47149084727 scopus 로고    scopus 로고
    • The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia
    • Van Vlierberghe P, van Grotel M, Tchinda J, Lee C, Beverloo HB, van der Spek PJ et al. (2008). The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia. Blood 111: 4668-4680.
    • (2008) Blood , vol.111 , pp. 4668-4680
    • Van Vlierberghe, P.1    van Grotel, M.2    Tchinda, J.3    Lee, C.4    Beverloo, H.B.5    van der Spek, P.J.6
  • 45
    • 41849142699 scopus 로고    scopus 로고
    • High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector
    • Zhang XB, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R et al. (2008). High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. J Clin Invest 118: 1502-1510.
    • (2008) J Clin Invest , vol.118 , pp. 1502-1510
    • Zhang, X.B.1    Beard, B.C.2    Trobridge, G.D.3    Wood, B.L.4    Sale, G.E.5    Sud, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.