Gene profiling and signaling pathways of Candida albicans keratitis

Molecular Vision

Volumn 14, Issue , 2008, Pages 1792-1798

  Yuan, Xiaoyong ^a   Mitchell, Bradley M ^a   Wilhelmus, Kirk R ^a,b  

^a CULLEN EYE INSTITUTE   (United States)

^b Department of Ophthalmology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN DERIVATIVE; RNA; TOLL LIKE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CANDIDA ALBICANS; CELL PROLIFERATION; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOKINE PRODUCTION; FEMALE; GENE CLUSTER; GENE EXPRESSION PROFILING; GENETIC CODE; GENETIC REGULATION; GENETIC SELECTION; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; INOCULATION; INTERCELLULAR SPACE; KERATOMYCOSIS; LEUKOCYTE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CANDIDA ALBICANS; CORNEA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; KERATITIS; MICE; MICE, INBRED BALB C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; WOUNDS AND INJURIES;

EID: 54449102440     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Srinivasan M. Fungal keratitis. Curr Opin Ophthalmol 2004; 15:321-7.
2. Sun RL, Jones DB, Wilhelmus KR. Clinical characteristics and outcome of Candida keratitis. Am J Ophthalmol 2007; 143:1043-5.
3. Thomas PA. Fungal infections of the cornea. Eye 2003; 17:852-62.
4. Jackson BE, Mitchell BM, Wilhelmus KR. Corneal virulence of Candida albicans strains deficient in Tup1-regulated genes. Invest Ophthalmol Vis Sci 2007; 48:2535-9.
5. Jackson BE, Wilhelmus KR, Hube B. The role of secreted aspartyl proteinases in Candida albicans keratitis. Invest Ophthalmol Vis Sci 2007; 48:3559-65.
6. Rohini G, Murugeswari P, Prajna NV, Lalitha P, Muthukkaruppan V. Matrix metalloproteinases (MMP-8, MMP-9) and the tissue inhibitors of metalloproteinases (TIMP-1, TIMP-2) in patients with fungal keratitis. Cornea 2007; 26:207-11.
7. Mitchell BM, Wu TG, Chong EM, Pate JC, Wilhelmus KR. Expression of matrix metalloproteinases 2 and 9 in experimental corneal injury and fungal keratitis. Cornea 2007; 26:589-93.
8. Mülhäuser J, Wildfeuer A, Meister H, Dybas L, Haferkamp O. Experimental Candida keratitis. histological, immunological and electron microscopical studies. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1975; 195:251-62.
9. Isobe Y. The effect of topical steroid medication on experimental Candida keratitis. Nippon Ganka Gakkai Zasshi 1991; 95:45-51.
10. Wang Y, Liu T, Gong H, Zhou Q, Sun S, Xie L. Gene profiling in murine corneas challenged with Aspergillus fumigatus. Mol Vis 2007; 13:1226-33.
11. Huang X, Hazlett LD. Analysis of Pseudomonas aeruginosa corneal infection using an oligonucleotide microarray. Invest Ophthalmol Vis Sci 2003; 44:3409-16.
12. Mitchell BM, Wu TG, Jackson BE, Wilhelmus KR. Candida albicans strain-dependent virulence and Rim13p-mediated filamentation in experimental keratomycosis. Invest Ophthalmol Vis Sci 2007; 48:774-80.
13. Wu TG, Wilhelmus KR, Mitchell BM. Experimental keratomycosis in a mouse model. Invest Ophthalmol Vis Sci 2003; 44:210-6.
14. Carvalho B, Bengtsson H, Speed TP, Irizarry RA. Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data. Biostatistics 2007; 8:485-99.
15. Storey JD, Dai JY, Leek JT. The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments. Biostatistics 2007; 8:414-32.
16. Rozell B, Ljungdahl PO, Martinez P. Host-pathogen interactions and the pathological consequences of acute systemic Candida albicans infections in mice. Curr Drug Targets 2006; 7:483-94.
17. Varela JC, Goldstein MH, Baker HV, Schultz GS. Microarray analysis of gene expression patterns during healing of rat corneas after excimer laser photorefractive keratectomy. Invest Ophthalmol Vis Sci 2002; 43:1772-82.
18. Cao Z, Wu HK, Bruce A, Wollenberg K, Panjwani N. Detection of differentially expressed genes in healing mouse corneas, using cDNA microarrays. Invest Ophthalmol Vis Sci 2002; 43:2897-904.
19. Jin X, Qin Q, Lin Z, Chen W, Qu J. Expression of toll-like receptors in the Fusarium solani infected cornea. Curr Eye Res 2008; 33:319-24.
20. Jin X, Qin Q, Tu L, Zhou X, Lin Y, Qu J. Toll-like receptors (TLRs) expression and function in response to inactivate hyphae of Fusarium solani in immortalized human corneal epithelial cells. Mol Vis 2007; 13:1953-61.
21. Zhao J, Wu XY. Aspergillus fumigatus antigens activate immortalized human corneal epithelial cells via toll-like receptors 2 and 4. Curr Eye Res 2008; 33:447-54.
22. Müller V, Viemann D, Schmidt M, Endres N, Ludwig S, Leverkus M, Roth J, Goebeler M. Candida albicans triggers activation of distinct signaling pathways to establish a proinflammatory gene expression program in primary human endothelial cells. J Immunol 2007; 179:8435-45.
23. Sun CC, Su Pang JH, Cheng CY, Cheng HF, Lee YS, Ku WC, Hsiao CH, Chen JK, Yang CM. Interleukin-1 receptor antagonist (IL-1RA) prevents apoptosis in ex vivo expansion of human limbal epithelial cells cultivated on human amniotic membrane. Stem Cells 2006; 24:2130-9.
24. Wu XY, Han SP, Ren MY, Chang Y, Yu FX. The role of NF-kappaB activation in lipopolysaccharide induced keratitis in rats. Chin Med J (Engl) 2005; 118:1893-9.
25. Khan S, Cole N, Hume EB, Garthwaite L, Conibear TC, Miles DH, Aliwaga Y, Krockenberger MB, Willcox MD. The role of CXC chemokine receptor 2 in Pseudomonas aeruginosa corneal infection. J Leukoc Biol 2007; 81:315-8.
26. van Enckevort FH, Netea MG, Hermus AR, Sweep CG, Meis JF, Van der Meer JW, Kullberg BJ. Increased susceptibility to systemic candidiasis in interleukin-6 deficient mice. Med Mycol 1999; 37:419-26.
27. Kim HS, Choi EH, Khan J, Roilides E, Francesconi A, Kasai M, Sein T, Schaufele RL, Sakurai K, Son CG, Greer BT, Chanock S, Lyman CA, Walsh TJ. Expression of genes encoding innate host defense molecules in normal human monocytes in response to Candida albicans. Infect Immun 2005; 73:3714-24.
28. Ashman RB, Farah CS, Wanasaengsakul S, Hu Y, Pang G, Clancy RL. Innate versus adaptive immunity in Candida albicans infection. Immunol Cell Biol 2004; 82:196-204.