Involvement of 15-lipoxygenase and prostaglandin EP receptors in aspirin- Triggered 15-hydroxyeicosatetraenoic acid generation in aspirin-sensitive asthmatics

Clinical and Experimental Allergy

Volumn 38, Issue 7, 2008, Pages 1108-1116

  Jedrzejczak Czechowicz, M ^a   Lewandowska Polak, A ^a   Bienkiewicz, B ^a   Kowalski, M L ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

15 HETE; Aspirin induced asthma; Aspitest; Lipoxygenase; Prostaglandin e receptors

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; ACETYLSALICYLIC ACID; ARACHIDONATE 15 LIPOXYGENASE; CAFFEIC ACID; MISOPROSTOL; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; SULPROSTONE; 15 HYDROXYEICOSATRIENOIC ACID; 15-HYDROXYEICOSATRIENOIC ACID; CAFFEIC ACID DERIVATIVE; DRUG DERIVATIVE; HYDROXYICOSATETRAENOIC ACID;

ADULT; AGED; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG HYPERSENSITIVITY; DRUG INDUCED DISEASE; FEMALE; HUMAN; LEUKOCYTE; MALE; PRIORITY JOURNAL; ADOLESCENT; DRUG ANTAGONISM; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; ARACHIDONATE 15-LIPOXYGENASE; ASPIRIN; ASTHMA; CAFFEIC ACIDS; DINOPROSTONE; DRUG HYPERSENSITIVITY; FEMALE; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; LEUKOCYTES; MALE; MIDDLE AGED; MISOPROSTOL; RECEPTORS, PROSTAGLANDIN E;

EID: 54449101241     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2008.02989.x     Document Type: Article

References (34)

1. Samter M, Beers RF. Intolerance to aspirin. Clinical studies and consideration of its pathogenesis. Ann Intern Med 1968; 68:975-83.
2. Szczeklik A, Stevenson DD. Aspirin-induced asthma: advances in pathogenesis, diagnosis, and management. J Allergy Clin Immunol 2003; 111:913-21.
3. Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G. Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. Br Med J 1975; 1:67-9.
4. Stevenson D D, Szczeklik A. Clinical and pathologic perspectives on aspirin sensitivity and asthma. J Allergy Clin Immunol 2006; 118:773-86.
5. Picado C. Mechanisms of aspirin sensitivity. Curr Allergy Asthma Rep 2006; 6:198-202.
6. Kumlin M, Dahlen B, Bjorck T, Zetterstrom 0, Granstrom E, Dahlen SE. Urinary excretion of leukotriene E4 and 11-dehydro- thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. Am Rev Respir Dis 1992; 146:96-103.
7. Pierzchalska M, Mastalerz L, Sanak M, Zazula M, Szczeklik A. A moderate and unspecific release of cysteinyl leukotrienes by aspirin from peripheral blood leucocytes precludes its value for aspirin sensitivity testing in asthma. Clin Exp Allergy 2000; 30:1785-91.
8. Celik G, Bavbek S, Misirligil Z, Melli M. Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prosta- glandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients. Clin Exp Allergy 2001; 31 :1615-22.
9. Gray PA, Warner TD, Vojnovic I et al. Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. Br J Pharmacol 2002; 137:1031-8.
10. Kowalski ML, Ptasinska A, Bienkiewicz B, Pawliczak R, DuBuske L. Differential effects of aspirin and misoprostol on 15-hydro- xyeicosatetraenoic acid generation by leukocytes from aspirin- sensitive asthmatic patients. J Allergy Clin Immunol 2003; 112:505-12.
11. Kowalski ML, Pawliczak R, Wozniak J et al. Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients. Am JRespir CritCareMed 2000; 161:391-8.
12. Szczeklik A, Mastalerz L, Nizankowska E, Cmiel A. Protective and bronchodilator effects of prostaglandin E and salbutamol in aspirin-induced asthma. Am J Respir Crit Care Med 1996; 153:567-71.
13. 2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma. Am J Respir Crit Care Med 1996; 153:572-5.
14. Szmidt M, Wasiak W. The influence of misoprostol (synthetic analogue of prostaglandin E1) on aspirin-induced bronchocon- striction in aspirin-sensitive asthma. J Invest Allergol Clin Immunol 1996; 6:121-5.
15. Kowalski ML, Makowska JS. Aspirin-exacerbated respiratory disease - an update on diagnosis and management. Allergy Clin Immunol Int 2006; 18:140-9.
16. Nizankowska E, Bestynska-Krypel A, Cmiel A, Szczeklik A. 0ral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma. Eur Respir J2000; 15:863-9.
17. Kowalski ML, Grzegorczyk J, Wojciechowska B, Poniatowska M. Intranasal challenge with aspirin induces cell influx and activation of eosinophils and mast cells in nasal secretions of ASA- sensitive patients. Clin Exp Allergy 1996; 26:807-14.
18. Kowalski ML, Grzelewska-Rzymowska I, Szmidt M, Rozniecki J. Clinical efficacy of aspirin in "desensitised" aspirin-sensitive asthmatics. Eur J Respir Dis 1986; 69:219-25.
19. Lewandowska-Polak A, Jedrzejczak M, Jarzebska M, Jankowski A, Kowalski ML. Mast cell and eosinophil derived mediators in nasal polyp dispersed cells from patients with hypersensitivity to aspirin. Abstract Book XXV Congress EAACI, 2006, N692, 198.
20. Holtzman MJ, Turk J, Shornick LP. Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells and save. J Biol Chem 1992; 267:21438-45.
21. Lecomte M, Laneuville 0, Ji C, DeWitt DL, Smith WL. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J Biol Chem 1994; 269: 13207-15.
22. Shureiqi I, Chen D, Lotan R et al. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res 2000; 60:6846-50.
23. Szczeklik A, Gryglewski RJ, 0lszewski E, Dembinska-Kiec A, Czerniawska-Mysik G. Aspirin-sensitive asthma: the effect of aspirin on the release of prostaglandins from nasal polyps. Pharmacol Res Commun 1977; 9:415-25.
24. Pierzchalska M, Szabo Z, Sanak M, Soja J, Szczeklik A. Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma. JAllergy ClinImmunol 2003; 111:1041-8.
25. Kowalski ML, Borowiec M, Pawliczak R, Kurowski M. Alternatively spliced variant of cyclooxygenase-1 gene is over expressed in leukocytes from patients with bronchial asthma and associated with aspirin-induced 15-HETE release. Allergy 2007; 62:628-34.
26. Picado C, Fernandez-Morata JC, Juan M et al. Cyclooxygenase-2 mRNA is down-expressed in nasal polyps from aspirin-sensitive asthmatics. Am JRespir Crit Care Med 1999; 160:291-6.
27. Narumiya S, FitzGerald GA. Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest 2001; 108:25-30.
28. Narumiya S, Sugimoto Y, Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 1999; 79: 1193-226.
29. Babakhin AA, Nolte H, DuBuske LM. Effect of misoprostol on the secretion of histamine from basophils of whole blood. Ann Allergy Asthma Immunol 2000; 84:361-5.
30. Perez-Novo CA, Claeys C, Van Cauwenberge P, Bachert C. Expression of eicosanoid receptors subtypes and eosinophilic inflammation: implication on chronic rhinosinusitis. Respir Res 2006; 7:75.
31. Park GY, Christman JW. Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases. Am J Physiol Lung Cell Mol Physiol 2006; 290:L797-805.
32. Ying S, Meng Q, Scanding G, Parkikh A, Corrigan CJ, Lee TH. Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cells. J Allergy ClinImmunol 2006; 117:312-8.
33. Borgland SL, Connor M, Ryan RM, Ball HJ, Christie MJ. Prosta- glandin E2 inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons. J Physiol 2002; 539:433-44.
34. Kanda N, Mitsiu H, Watanabe S. Prostaglandin E(2) suppresses CCL27 production through EP2 and EP3 receptors in human keratinocytes. J Allergy ClinImmunol 2004; 114:1403-9.