Characteristics of uncontrolled hemorrhage in cardiac surgery

Journal of Extra-Corporeal Technology

Volumn 40, Issue 2, 2008, Pages 89-93

  Trowbridge, Cody ^a   Stammers, Alfred ^a   Klayman, Myra ^a   Brindisi, Nicholas ^a   Woods, Edward ^a  

^a GEISINGER MEDICAL CENTER   (United States)

Author keywords

Cardiac surgery; Hemorrhage; Recombinant factor VIIa

Indexed keywords

ALPHA1 PROTEINASE INHIBITOR III; APROTININ; BLOOD CLOTTING FACTOR; FRESH FROZEN PLASMA; RECOMBINANT BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 7A; RECOMBINANT FVIIA; RECOMBINANT PROTEIN;

AGED; AORTA SURGERY; BLEEDING; BLOOD AUTOTRANSFUSION; CONFERENCE PAPER; CONTROLLED STUDY; CRYOPRECIPITATE; DISEASE CONTROL; ERYTHROCYTE TRANSFUSION; EXTRACORPOREAL CIRCULATION; HEART ARREST; HEART SURGERY; HUMAN; MAJOR CLINICAL STUDY; THROMBOCYTE TRANSFUSION; ARTICLE; BLOOD COMPONENT THERAPY; CARDIOPULMONARY BYPASS; CASE CONTROL STUDY; MIDDLE AGED; PROSPECTIVE STUDY;

AGED; BLOOD COMPONENT TRANSFUSION; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION, AUTOLOGOUS; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; CASE-CONTROL STUDIES; FACTOR VIIA; HEART ARREST, INDUCED; HEMORRHAGE; HUMANS; MIDDLE AGED; PROSPECTIVE STUDIES; RECOMBINANT PROTEINS;

EID: 54449084437     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (14)

1. Herwaldt LA, Swartzendruber SK, Edmond MB, et al. The epidemiology of hemorrhage related to cardiothoracic operations. Infect Control Hosp Epidemiol. 1998;19:6-8.
2. Karkouti K, Wijeysundera DN, Yau TM, et al. The independent association of massive blood loss with mortality in cardiac surgery. Transfusion. 2004;44:1453-62.
3. Bishop CV, Renwick WE, Hogan C, et al. Recombinant activated factor VII: treating postoperative hemorrhage in cardiac surgery. Ann Thorac Surg. 2006;81:875-9.
4. von Heymann C, Redlich U, Jain U, et al. Recombinant activated factor VII for refractory bleeding after cardiac surgery - a retrospective analysis of safety and efficacy. Crit Care Med. 2005;33:2241-6.
5. Diprose P, Herbertson MJ, O'Shaughnessy D, Gill RS. Activated recombinant factor VII after cardiopulmonary bypass reduces allogeneic transfusion in complex non-coronary cardiac surgery: randomized double-blind placebo-controlled pilot study. Br J Anaesth. 2005;95:596-602.
6. Raivio P, Suojaranta-Ylinen R, Kuitunen AH. Recombinant factor VIIa in the treatment of postoperative hemorrhage after cardiac surgery. Ann Thorac Surg. 2005;80:66-71.
7. Gowers CJ, Parr MJ. Recombinant activated factor VIIa use in massive transfusion and coagulopathy unresponsive to conventional therapy. Anaesth Intensive Care. 2005;33:196-200.
8. Hyllner M, Houltz E, Jeppsson A. Recombinant activated factor VII in the management of life-threatening bleeding in cardiac surgery. Eur J Cardiothorac Surg. 2005;28:254-8.
9. Novo Nordisk, NovoSeven Coagulation Factor VIIa (Recombinant) Package Insert. Bagsvaerd, Denmark: Novo Nordisk; 1999.
10. Kalweit G, Bach J, Huwer H, Winning J, Hellstern P. The impact of cardiac ischemia and reperfusion on markers of activated haemostasis and fibrinolysis during cardiopulmonary bypass: comparison of plasma levels in arterial and coronary venous blood. Thromb Res. 2005;116:33-9.
11. Bull BS, Hay K, Razzouk AJ, Huse WM. Reinfusion of aspirated pericardial blood during CPB. Part II. Laparotomy sponges are hazardous parts of the CPB circuit? Blood Cells Mol Dis. 2005;34:144-50.
12. Higgins TL, Estafanous FG, Loop FD, et al. Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients, a clinical severity score. JAMA. 1992; 268:1860.
13. Dial S, Delabays E, Albert M, et al. Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass. Thorac Cardiovasc Surg. 2005;130:654-61.
14. Koster A, Bottcher W, Merkel F, Hetzer R, Kuppe H. The more closed the bypass system the better: a pilot study on the effects of reduction of cardiotomy suction and passive venting on hemostatic activation during on-pump coronary artery bypass grafting. Perfusion. 2005;20:285-8.