Psychopharmacology of anticonvulsants: Levetiracetam as a synaptic vesicle protein modulator

Journal of Clinical Psychiatry

Volumn 65, Issue 9, 2004, Pages 1162-1163

  Stahl, Stephen M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NEUROSCIENCE EDUCATION INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANTICONVULSIVE AGENT; DRUG DERIVATIVE; ETIRACETAM; MEMBRANE PROTEIN; NERVE PROTEIN; PIRACETAM; SV2A PROTEIN, HUMAN; SV2A PROTEIN, MOUSE;

ANIMAL; ARTICLE; DISEASE MODEL; DRUG EFFECT; EXOCYTOSIS; HUMAN; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PROTEIN BINDING; SEIZURE; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; EXOCYTOSIS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROTRANSMITTER AGENTS; PIRACETAM; PROTEIN BINDING; SEIZURES; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES;

EID: 5444272998     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v65n0901     Document Type: Short Survey

References (15)

1. Stahl SM. Psychopharmacology of anticonvulsants: do all anticonvulsants have the same mechanism of action? [BRAINSTORMS] J Clin Psychiatry 2004;65:149-150
2. Stahl SM. Anticonvulsants as anxiolytics, pt 1: tiagabine and other anticonvulsants with actions on GABA [BRAINSTORMS]. J Clin Psychiatry 2004;65:291-292
3. 2δ ligands at voltage-gated calcium channels [BRAINSTORMS]. J Clin Psychiatry 2004;65:460-461
4. 2δ ligands at voltage-gated calcium channels [BRAINSTORMS]. J Clin Psychiatry 2004;65:596-597
5. Stahl SM. Anticonvulsants as mood stabilizers and adjuncts to antipsychotics: valproate, lamotrigine, carbamazepine, oxcarbazepine and actions at voltage sensitive sodium channels [BRAINSTORMS]. J Clin Psychiatry 2004;65:738-739
6. Stahl SM. Mechanism of action of voltage sensitive sodium channel (VSSC) modulators [BRAINSTORMS]. J Clin Psychiatry 2004;65:894-895
7. Stahl SM. Mechanism of action of voltage sensitive calcium channel (VSCC) modulators [BRAINSTORMS]. J Clin Psychiatiy 2004;65:1033-1034
8. Lynch BA, Lambeng N, Nocka K, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A 2004;101:9861-9866 (Pubitemid 38869327)
9. Gillard M, Fuks B, Michel P, et al. Binding characteristics of [3H]ucb 30889 to levetiracetam binding sites in rat brain. Eur J Pharmacol 2003;478:1-9 (Pubitemid 38366068)
10. Grunze H, Langosch J, Born C, et al. Levetiracetam in the treatment of acute mania: an open add-on study with an on-off-on design. J Clin Psychiatry 2003;64:781-784 (Pubitemid 36897214)
11. Ardid D, Lamberty Y, Alloui A, et al. Antihyperalgesic effect of levetiracetam in neuropathic pain models in rats. Eur J Pharmacol 2003;473:27-33 (Pubitemid 36851625)
12. Rowbotham MC, Manville NS, Ren J. Pilot tolerability and effectiveness study of levetiracetam for postherpetic neuralgia. Neurology 2003;61:866-867 (Pubitemid 37174499)
13. Bajjalieh SM, Frantz GD, Weimann JM. Differential expression of synaptic vesicle protein 2 (SV2) isoforms. J Neurosci 1994;14:5223-5225 (Pubitemid 24279045)
14. Crowder KM, Gunther JM, Jones RA, et al. Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci U S A 1999;96:15268-15273 (Pubitemid 30019801)
15. 2+ regulators in neurotransmitter release. Neuron 1999;24:1003-1016 (Pubitemid 30017678)