메뉴 건너뛰기




Volumn 62, Issue 3 B, 2004, Pages 751-755

Hyperphosphorylated tau protein in the cerebrospinal fluid of patients with Alzheimer's disease and other dementias: Preliminary findings

Author keywords

Alzheimer's disease; Cerebrospinal fluid; Differential diagnosis; Tau protein

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; PHOSPHOPROTEIN; PHOSPHOTAU PROTEIN; TAU PROTEIN; THREONINE; UNCLASSIFIED DRUG;

EID: 5444233547     PISSN: 0004282X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0004-282X2004000500001     Document Type: Article
Times cited : (5)

References (30)
  • 2
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3
  • 4
    • 0032033766 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau protein as a potential diagnostic marker in Alzheimer's disease
    • Arai H, Clark CM, Ewbank DC, et al. Cerebrospinal fluid tau protein as a potential diagnostic marker in Alzheimer's disease. Neurobiol Aging 1998;19:125-126.
    • (1998) Neurobiol Aging , vol.19 , pp. 125-126
    • Arai, H.1    Clark, C.M.2    Ewbank, D.C.3
  • 5
    • 0029609264 scopus 로고
    • Tau protein in cerebrospinal fluid: A biochemical marker for axonal degeneration in Alzheimer disease?
    • Blennow K, Wallin A, Agren H, Spenger C, Siegfried J, Vanmechelen E. Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease? Mol Chem Neuropathol 1995;26:231-245.
    • (1995) Mol Chem Neuropathol , vol.26 , pp. 231-245
    • Blennow, K.1    Wallin, A.2    Agren, H.3    Spenger, C.4    Siegfried, J.5    Vanmechelen, E.6
  • 6
    • 0344726167 scopus 로고
    • Antemortem CSF tau is related to neuronal pathology at autopsy in Alzheimer's disease
    • Galasko D, Hansen L Vigo-Pelfrey C, et al. Antemortem CSF tau is related to neuronal pathology at autopsy in Alzheimer's disease. Soc Neurosci Abstr 1995;581.
    • (1995) Soc Neurosci Abstr , pp. 581
    • Galasko, D.1    Hansen, L.2    Vigo-Pelfrey, C.3
  • 7
    • 0027308924 scopus 로고
    • Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
    • Bramblett GT, Goedert M, Jakes R, Merrick SE, Trojanowski JQ, Lee VM. Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron 1993;10:1089-1099.
    • (1993) Neuron , vol.10 , pp. 1089-1099
    • Bramblett, G.T.1    Goedert, M.2    Jakes, R.3    Merrick, S.E.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 8
    • 0028935052 scopus 로고
    • Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease
    • Vigo-Pelfrey C, Seubert P, Barbour R, et al. Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology 1995;45:788-793.
    • (1995) Neurology , vol.45 , pp. 788-793
    • Vigo-Pelfrey, C.1    Seubert, P.2    Barbour, R.3
  • 9
    • 0032033832 scopus 로고    scopus 로고
    • Consensus report of the working group on: "Molecular and biochemical markers of Alzheimer's disease"
    • The Ronald and Nancy Reagan Research Institute of the Alzheimer's Association and the National Institute on Aging Working Group
    • Consensus report of the Working Group on: "Molecular and Biochemical Markers of Alzheimer's Disease". The Ronald and Nancy Reagan Research Institute of the Alzheimer's Association and the National Institute on Aging Working Group. Neurobiol Aging 1998;19:109-116.
    • (1998) Neurobiol Aging , vol.19 , pp. 109-116
  • 10
    • 0032857103 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment
    • Andreasen N, Minthon L, Vanmechelen E, et al. Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment. Neurosci Lett 1999;273:5-8.
    • (1999) Neurosci Lett , vol.273 , pp. 5-8
    • Andreasen, N.1    Minthon, L.2    Vanmechelen, E.3
  • 11
    • 0037244487 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of total-tau, phospho-tau and AB42 predicts development of Alzheimer's disease in patients with mild cognitive impairment
    • Andreasen N, Vanmechelen E, Vanderstichele H, et al. Cerebrospinal fluid levels of total-tau, phospho-tau and AB42 predicts development of Alzheimer's disease in patients with mild cognitive impairment. Acta Neurol Scand. 2003;179:(Suppl)47-51.
    • (2003) Acta Neurol Scand , vol.179 , Issue.SUPPL. , pp. 47-51
    • Andreasen, N.1    Vanmechelen, E.2    Vanderstichele, H.3
  • 12
    • 0037040525 scopus 로고    scopus 로고
    • Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients
    • Hu YY, He SS, Wang XC, et al. Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients. Neurosci Lett 2002;320:156-160.
    • (2002) Neurosci Lett , vol.320 , pp. 156-160
    • Hu, Y.Y.1    He, S.S.2    Wang, X.C.3
  • 13
    • 0032581113 scopus 로고    scopus 로고
    • Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease
    • Shoji M, Matsubara E, Kanai M, et al. Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease. J Neurol Sci 1998;158:134-140.
    • (1998) J Neurol Sci , vol.158 , pp. 134-140
    • Shoji, M.1    Matsubara, E.2    Kanai, M.3
  • 14
    • 0037514257 scopus 로고    scopus 로고
    • Decreased B-amyloid and increased tau levels in cerebrospinal fluid of patients with Alzheimer's disease
    • Sunderland T, Linker G, Mirza N, et al. Decreased B-amyloid and increased tau levels in cerebrospinal fluid of patients with Alzheimer's disease. JAMA 2003;289:2094-2103.
    • (2003) JAMA , vol.289 , pp. 2094-2103
    • Sunderland, T.1    Linker, G.2    Mirza, N.3
  • 15
    • 14444269228 scopus 로고    scopus 로고
    • Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: A study in Japan
    • Kanai M, Matsubara E, Isoe K, et al. Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol 1998;44:17-26.
    • (1998) Ann Neurol , vol.44 , pp. 17-26
    • Kanai, M.1    Matsubara, E.2    Isoe, K.3
  • 16
    • 0034892016 scopus 로고    scopus 로고
    • Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: A discrimination from Alzheimer's disease?
    • Kapaki E, Kilidireas K, Paraskevas GP, Michalopoulou M, Patsouris E. Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer's disease? J Neurol Neurosurg Psychiatry 2001;71:401-403.
    • (2001) J Neurol Neurosurg Psychiatry , vol.71 , pp. 401-403
    • Kapaki, E.1    Kilidireas, K.2    Paraskevas, G.P.3    Michalopoulou, M.4    Patsouris, E.5
  • 17
    • 0037062351 scopus 로고    scopus 로고
    • Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration
    • Riemenschneider M, Wagenpfeil S, Diehl J, et al. Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration. Neurology 2002;58:1622-1628.
    • (2002) Neurology , vol.58 , pp. 1622-1628
    • Riemenschneider, M.1    Wagenpfeil, S.2    Diehl, J.3
  • 18
    • 0027374233 scopus 로고
    • Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay
    • Vandermeeren M, Mercken M, Vanmechelen E, et al. Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. J Neurochem 1993;61:1828-1834.
    • (1993) J Neurochem , vol.61 , pp. 1828-1834
    • Vandermeeren, M.1    Mercken, M.2    Vanmechelen, E.3
  • 19
    • 0033618534 scopus 로고    scopus 로고
    • Phosphorylated tau in human cerebrospinal fluid is a diagnostic marker for Alzheimer's disease
    • Ishiguro K, Ohno H Arai H, et al. Phosphorylated tau in human cerebrospinal fluid is a diagnostic marker for Alzheimer's disease. Neurosci Lett 1999;270:91-94.
    • (1999) Neurosci Lett , vol.270 , pp. 91-94
    • Ishiguro, K.1    Ohno, H.2    Arai, H.3
  • 20
    • 0011975596 scopus 로고    scopus 로고
    • CSF-phosphotau (181P) as a promising marker for discriminating Alzheimer's disease from dementia with Lewy bodies
    • Iqbal K, Sisodia SS, Winblad B (eds). Chichester: John Willey Sons
    • Vanmechelen E, Van Kerschaver E, Blennow K, et al. CSF-phosphotau (181P) as a promising marker for discriminating Alzheimer's disease from dementia with Lewy bodies. In Iqbal K, Sisodia SS, Winblad B (eds). Alzheimer's disease: advances in ethiology pathogenesis and therapeutics. Chichester: John Willey Sons; 2001:285-291.
    • (2001) Alzheimer's Disease: Advances in Ethiology Pathogenesis and Therapeutics , pp. 285-291
    • Vanmechelen, E.1    Van Kerschaver, E.2    Blennow, K.3
  • 21
    • 0035261534 scopus 로고    scopus 로고
    • CSF phosphorylated tau is a possible marker for discriminating Alzheimer's disease from dementia with Lewy bodies
    • Phospho-Tau International Study Group
    • Parnetti L, Lanari A, Amici S, Gallai V, Vanmechelen E, Hulstaert F. CSF phosphorylated tau is a possible marker for discriminating Alzheimer's disease from dementia with Lewy bodies. Phospho-Tau International Study Group. Neurol Sci 2001;22:77-78.
    • (2001) Neurol Sci , vol.22 , pp. 77-78
    • Parnetti, L.1    Lanari, A.2    Amici, S.3    Gallai, V.4    Vanmechelen, E.5    Hulstaert, F.6
  • 22
    • 0027361281 scopus 로고
    • Microtubule-associated protein tau: Abnormal phosphorylation of a non- paired helical filament pool in Alzheimer disease
    • Kopke E, Tung YC, Shaikh S, Alonso AC, Iqbal K, Grundke-Iqbal I. Microtubule-associated protein tau: abnormal phosphorylation of a non- paired helical filament pool in Alzheimer disease. J Biol Chem 1993;268:24374-24384.
    • (1993) J Biol Chem , vol.268 , pp. 24374-24384
    • Kopke, E.1    Tung, Y.C.2    Shaikh, S.3    Alonso, A.C.4    Iqbal, K.5    Grundke-Iqbal, I.6
  • 23
    • 0035033619 scopus 로고    scopus 로고
    • Both total and phosphorylated tau are increased in Alzheimer's disease
    • Sjogren M, Davidsson P, Tullberg M, et al. Both total and phosphorylated tau are increased in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2001;70:624-360.
    • (2001) J Neurol Neurosurg Psychiatry , vol.70 , pp. 624-360
    • Sjogren, M.1    Davidsson, P.2    Tullberg, M.3
  • 24
    • 0034607960 scopus 로고    scopus 로고
    • Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: A sandwich ELISA with a synthetic phosphopeptide for standardization
    • Vanmechelen E, Vanderstichele H, Davidsson P, et al. Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization. Neurosci Lett 2000;285:49-52.
    • (2000) Neurosci Lett , vol.285 , pp. 49-52
    • Vanmechelen, E.1    Vanderstichele, H.2    Davidsson, P.3
  • 25
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADR-DA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADR-DA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 26
    • 0028223015 scopus 로고
    • Clinical and neuropathological criteria for frontotemporal dementia
    • The Lund and Manchester Groups
    • Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups. J Neurol Neurosurg Psychiatry 1994;57:416-418.
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 416-418
  • 27
    • 0028240447 scopus 로고
    • Clinical criteria for vascular dementia: The NINDS-AIREN criteria
    • Erkinjuntti T. Clinical criteria for vascular dementia: the NINDS-AIREN criteria. Dementia 1994;5:189-192.
    • (1994) Dementia , vol.5 , pp. 189-192
    • Erkinjuntti, T.1
  • 28
    • 0006164301 scopus 로고    scopus 로고
    • Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop
    • McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 1996;47:1113-1124.
    • (1996) Neurology , vol.47 , pp. 1113-1124
    • McKeith, I.G.1    Galasko, D.2    Kosaka, K.3
  • 30
    • 0037183481 scopus 로고    scopus 로고
    • CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects
    • Buerger K, Teipel SJ, Zinkowski R, et al. CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects. Neurology 2002;59:627-629.
    • (2002) Neurology , vol.59 , pp. 627-629
    • Buerger, K.1    Teipel, S.J.2    Zinkowski, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.