In vivo and in vitro chondrotoxicity of ciprofloxacin in juvenile rats

Acta Pharmacologica Sinica

Volumn 25, Issue 10, 2004, Pages 1262-1266

  Li, Ping ^a   Cheng, Neng Neng ^a   Chen, Bin Yan ^a   Wang, Yong Ming ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Articular cartilage; Cell survival; Ciprofloxacin; Glycosaminoglycans; Juvenile rats; Knee joints; Toxicokinetics

Indexed keywords

1,9 DIMETHYLMETHYLENE BLUE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CIPROFLOXACIN; METHYLENE BLUE; PROTEOGLYCAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL DEATH; CELL PROLIFERATION; CHONDROPATHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG TISSUE LEVEL; ESCHERICHIA COLI; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; KNEE; MALE; NONHUMAN; PROTEOGLYCAN SYNTHESIS; RAT; RAT STRAIN; RISK ASSESSMENT; RISK FACTOR; THICKNESS; TOXICOKINETICS;

ANIMALS; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; CARTILAGE, ARTICULAR; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CIPROFLOXACIN; MALE; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 5444227028     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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