Changes in glial fibrillary acidic protein immunoreactivity in the dentate gyrus and hippocampus proper of adult and aged dogs

Journal of Veterinary Medical Science

Volumn 70, Issue 9, 2008, Pages 965-969

  Hwang, In Koo ^a   Choi, Jung Hoon ^b   Li, Hua ^b   Yoo, Ki Yeon ^b   Kim, Dae Won ^c   Lee, Choong Hyun ^a   Yi, Sun Shin ^a   Seong, Je Kyung ^a   Lee, In Se ^a   Yoon, Yeo Sung ^a   Won, Moo Ho ^b  

^a Seoul National University   (South Korea)

^b Hallym University   (South Korea)

^c Natural F and P Co Ltd   (South Korea)

Author keywords

Aging; Astrocyte; Canine; Glial fibrillary acidic protein; Hippocampus

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN;

AGE; ANIMAL; ARTICLE; ASTROCYTE; COMPARATIVE STUDY; CYTOLOGY; DENTATE GYRUS; DOG; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; WESTERN BLOTTING;

AGE FACTORS; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; DENTATE GYRUS; DOGS; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY;

CANIS FAMILIARIS;

EID: 54349087354     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.70.965     Document Type: Article

References (27)

1. Bjorklund, H., Eriksodotter-Nilsson, M., Dahl, D., Rose, G., Hoffer, B. and Olsen, L. 1985. Image analysis of GFA-positive astrocytes from adolescence to senescence. Exp. Brain Res. 58: 163-170.
2. Borràs, D., Ferrer, I. and Pumarola, M. 1999. Age-related changes in the brain of the dog. Vet. Pathol. 36: 202-211.
3. Cummings, B.J., Head, E., Ruehl, W.W., Milgram, N.W. and Cotman, C.W. 1996. The canine as an animal model of human aging and dementia. Neurobiol. Aging 17: 259-268.
4. Dahl, D. and Bignami, A. 1985. Intermediate filaments in nervous tissue. Cell Muscle Motil. 6: 75-96.
5. Dong, H., Martin, M.V., Chambers, S. and Csernansky, J.G. 2007. Spatial relationship between synapse loss and β-amyloid deposition in Tg2576 mice. J. Comp. Neurol. 500: 311-321.
6. Eichenbaum, H. 2001. The hippocampus and declarative memory: cognitive mechanisms and neural codes. Behav. Brain Res. 127: 199-207.
7. Hansen, L.A., Armstrong, D.M. and Terry, R.D. 1987. An immunohistochemical quantification on fibrous astrocytes in the aging human cerebral cortex. Neurobiol. Aging 8: 1-6.
8. Hatten, M.E., Liem, R.K., Shelanski, M.L. and Mason, C.A. 1991. Astroglia in CNS injury. Glia 4: 233-243.
9. Hayakawa, N., Kato, H. and Araki, T. 2007. Age-related changes of astrocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sector. Mech. Ageing Dev. 128: 311-316.
10. Head, E., Callahan, H., Muggenburg, B.A., Cotman, C.W. and Milgram, N.W. 1998. Visual-discrimination learning ability and beta-amyloid accumulation in the dog. Neurobiol. Aging 19: 415-425.
11. Hwang, I.K., Yoon, Y.S., Yoo, K.Y., Li, H., Sun, Y., Choi, J.H., Lee, C.H., Huh, S.O., Lee, Y.L. and Won, M.H. 2008. Sustained expression of parvalbumin immunoreactivity in the hippocampal CA1 region and dentate gyrus during aging in dogs. Neurosci. Lett. 434: 99-103.
12. Johnstone, E.M., Chaney, M.O., Norris, F.H., Pascual, R. and Little, S.P. 1991. Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis. Brain Res. Mol. Brain Res. 10: 299-305.
13. Kohama, S.G., Gross, J.R., Finch, C.E. and McNeil, T.H. 1995. Increases of glial fibrillary acidic protein in the aging female mouse brain. Neurobiol. Aging 16: 59-67.
14. Lim, R.K.S., Liu, C.N. and Moffitt, R.L. 1960. A Stereotaxic Atlas of the Dogs Brain, Charles C, Thomas, Springfield.
15. Long, J.M., Kalehua, A.N., Muth, N.J., Calhoun, M.E., Jucker, M., Hengemihle, J.M., Ingram, D.K. and Mouton, P.R. 1998. Stereological analysis of astrocytes and microglia in aging mouse hippocampus. Neurobiol. Aging 19: 497-503.
16. Matsuki, N., Fujiwara, K., Tamahara, S., Uchida, K., Matsunaga, S., Nakayama, H., Doi, K., Ogawa, H. and Ono, K. 2004. Prevalence of autoantibody in cerebrospinal fluids from dogs with various CNS diseases. J. Vet. Med. Sci. 66: 295-297.
17. Mesulam, M.M. 1999. Neuroplasticity failure in Alzheimer's disease: bridging the gap between plaques and tangles. Neuron 24: 521-529.
18. Miller, D.B. and O'Callahan, J.P. 2005. Aging, stress and the hippocampus. Ageing Res. Rev. 4: 123-140.
19. Mouton, P.R., Long, J.M., Lei, D.L., Howard, V., Jucker, M., Calhoun, M.E. and Ingram, D.K. 2002. Age and gender effects on microglia and astrocyte numbers in brains of mice. Brain Res. 956: 30-35.
20. Nichols, N.R., Day, J.R., Laping, N.J., Johnson, S.A. and Finch, C.E. 1993. GFAP mRNA increases with age in rat and human brain. Neurobiol. Aging 14: 421-429.
21. O'Callaghan, J.P. and Miller, D.B. 1991. The concentration of glial fibrillary acidic protein increases with age in the mouse and rat brain. Neurobiol. Aging 12: 171-174.
22. Pekny, M. and Pekna, M. 2004. Astrocyte intermediate filaments in CNS pathologies and regeneration. J. Pathol. 204: 428-437.
23. Pilegaard, K. and Ladefoged, O. 1996. Total number of astrocytes in the molecular layer of the dentate gyrus of rats at different ages. Anal. Quant. Cytol. Histol. 18: 279-285.
24. Shibuya, M., Matsuki, N., Fujiwara, K., Imajoh-Ohmi, S., Fukuda, H., Pham, N.T., Tamahara, S. and Ono, K. 2007. Autoantibodies against glial fibrillary acidic protein (GFAP) in cerebrospinal fluids from Pug dogs with necrotizing meningoencephalitis. J. Vet. Med. Sci. 69: 241-245.
25. Shimada, A., Kuwamura, M., Awakura, T., Umemura, T. and Itakura, C. 1992. An immunohistochemical and ultrastructural study on age-related astrocytic gliosis in the central nervous system of dogs. J. Vet. Med. Sci. 54: 29-36.
26. West, M.J., Kawas, C.H., Stewart, W.F., Rudow, G.L. and Troncoso, J.C. 2004. Hippocampal neurons in pre-clinical Alzheimer's disease. Neurobiol. Aging 25: 1205-1212.
27. Wu, Y., Zhang, A.Q. and Yew, D.T. 2005. Age related changes of various markers of astrocytes in senescence-accelerated mice hippocampus. Neurochem. Int. 46: 565-574.