메뉴 건너뛰기




Volumn 30, Issue 6, 2008, Pages 491-501

The doppel (Dpl) protein influences in vitro migration capability in astrocytoma-derived cells

Author keywords

Antisense oligonucleotide; Gene silencing; Glial tumor; HeLa; IPDDC A2; Migration scratch assay; Prion like proteins; siRNA

Indexed keywords

PRION PROTEIN; PROTEIN DOPPEL; SMALL INTERFERING RNA; TETRAZOLIUM; UNCLASSIFIED DRUG;

EID: 54249165890     PISSN: 15705870     EISSN: None     Source Type: Journal    
DOI: 10.3233/CLO-2008-0437     Document Type: Article
Times cited : (8)

References (57)
  • 2
    • 33845915668 scopus 로고    scopus 로고
    • The prion-like protein doppel (Dpl) interacts with the human receptor for activated C-kinase 1 (RACK1) protein
    • A. Azzalin, I. Del Vecchio, L. Ferretti et al., The prion-like protein doppel (Dpl) interacts with the human receptor for activated C-kinase 1 (RACK1) protein, Anticancer Research 26 (2006), 4539-4548.
    • (2006) Anticancer Research , vol.26 , pp. 4539-4548
    • Azzalin, A.1    Del Vecchio, I.2    Ferretti, L.3
  • 3
    • 0026707640 scopus 로고
    • Establishment and characterization of two cell lines derived from human glioblastoma multiforme
    • G. Bacciocchi, N. Gibelli, C. Zibera et al., Establishment and characterization of two cell lines derived from human glioblastoma multiforme, Anticancer Research 12 (1992), 853-861.
    • (1992) Anticancer Research , vol.12 , pp. 853-861
    • Bacciocchi, G.1    Gibelli, N.2    Zibera, C.3
  • 4
    • 0022485676 scopus 로고
    • D-1 dopaminergic and β-adrenergic stimulation of adenylate cyclase in a clone derived from the human astrocytoma cell line G-CCM
    • A.J. Balmfort, S.G. Ball, R.I. Freshney et al., D-1 dopaminergic and β-adrenergic stimulation of adenylate cyclase in a clone derived from the human astrocytoma cell line G-CCM, Journal Neurochemistry 47 (1986), 715-719.
    • (1986) Journal Neurochemistry , vol.47 , pp. 715-719
    • Balmfort, A.J.1    Ball, S.G.2    Freshney, R.I.3
  • 5
    • 0036498430 scopus 로고    scopus 로고
    • Small is not beautiful: Antagonizing functions for the prion protein PrP(C) and its homologue Dpl
    • A. Behrens and A. Aguzzi, Small is not beautiful: antagonizing functions for the prion protein PrP(C) and its homologue Dpl, Trends in Neuroscience 25 (2002), 150-154.
    • (2002) Trends in Neuroscience , vol.25 , pp. 150-154
    • Behrens, A.1    Aguzzi, A.2
  • 6
    • 0037099695 scopus 로고    scopus 로고
    • Absence of the prion protein homologue doppel causes male sterility
    • A. Behrens, S. Brandner, N. Genoud et al., Absence of the prion protein homologue doppel causes male sterility, EMBO Journal 21 (2002), 3652-3658.
    • (2002) EMBO Journal , vol.21 , pp. 3652-3658
    • Behrens, A.1    Brandner, S.2    Genoud, N.3
  • 7
    • 34249889900 scopus 로고    scopus 로고
    • Mechanisms of disease: Genetic predictors of response to treatment in brain tumors
    • V.P. Collins, Mechanisms of disease: genetic predictors of response to treatment in brain tumors, Nature Clinical Practice Oncology 4 (2006), 362-374.
    • (2006) Nature Clinical Practice Oncology , vol.4 , pp. 362-374
    • Collins, V.P.1
  • 8
    • 33845920974 scopus 로고    scopus 로고
    • Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells,
    • S. Comincini, L.R. Chiarelli, P. Zelini et al., Nuclear mRNA retention and aberrant doppel protein expression in human astrocytic tumor cells, Oncology Reports 16 (2006), 1325-1332.
    • (2006) Oncology Reports , vol.16 , pp. 1325-1332
    • Comincini, S.1    Chiarelli, L.R.2    Zelini, P.3
  • 9
    • 33845935837 scopus 로고    scopus 로고
    • The doppel gene biology: A scientific journey from brain to testis, and return
    • S. Comincini, I. Del Vecchio and A. Azzalin, The doppel gene biology: a scientific journey from brain to testis, and return, Central European Journal of Biology 1 (2006), 494-505.
    • (2006) Central European Journal of Biology , vol.1 , pp. 494-505
    • Comincini, S.1    Del Vecchio, I.2    Azzalin, A.3
  • 10
    • 3242717853 scopus 로고    scopus 로고
    • Differential expression of the prion-like protein doppel gene (PRND) in astrocytomas: A new molecular marker potentially involved in tumor progression
    • S. Comincini, A. Facoetti, I. Del Vecchio et al., Differential expression of the prion-like protein doppel gene (PRND) in astrocytomas: a new molecular marker potentially involved in tumor progression, Anticancer Research 24 (2004), 1507-1517.
    • (2004) Anticancer Research , vol.24 , pp. 1507-1517
    • Comincini, S.1    Facoetti, A.2    Del Vecchio, I.3
  • 11
    • 34548583594 scopus 로고    scopus 로고
    • S. Comincini, V. Ferrara, A. Arias et al., Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy, Oncology Reports 17 (2007), 989-996.
    • S. Comincini, V. Ferrara, A. Arias et al., Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy, Oncology Reports 17 (2007), 989-996.
  • 12
    • 33845780974 scopus 로고    scopus 로고
    • RNA learns from antisense
    • D.R. Corey, RNA learns from antisense, Nature Chemical Biology 3 (2007), 8-11.
    • (2007) Nature Chemical Biology , vol.3 , pp. 8-11
    • Corey, D.R.1
  • 13
    • 0037329051 scopus 로고    scopus 로고
    • RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site
    • E.A. Cox, D. Bennin, A.T. Doan et al., RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site, Molecular Biology of the Cell 14 (2003), 658-669.
    • (2003) Molecular Biology of the Cell , vol.14 , pp. 658-669
    • Cox, E.A.1    Bennin, D.2    Doan, A.T.3
  • 14
    • 23844525977 scopus 로고    scopus 로고
    • Functional mapping of the bovine doppel gene promoter region
    • I. Del Vecchio, A. Azzalin, E. Guidi et al., Functional mapping of the bovine doppel gene promoter region, Gene 356 (2005), 101-108.
    • (2005) Gene , vol.356 , pp. 101-108
    • Del Vecchio, I.1    Azzalin, A.2    Guidi, E.3
  • 15
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • T. Demuth and M.E. Berens, Molecular mechanisms of glioma cell migration and invasion, Journal of Neuro-Oncology 70 (2004), 217-228.
    • (2004) Journal of Neuro-Oncology , vol.70 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 16
    • 41349091447 scopus 로고    scopus 로고
    • Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines
    • T. Demuth, J.L. Rennet, D.B. Hoelzinger et al., Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines, BMC Genomics 29 (2008), 9-54.
    • (2008) BMC Genomics , vol.29 , pp. 9-54
    • Demuth, T.1    Rennet, J.L.2    Hoelzinger, D.B.3
  • 18
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • A. Giese, R. Bjerkvig, M.E. Berens et al., Cost of migration: invasion of malignant gliomas and implications for treatment, Journal Clinical Oncology 21 (2003), 1624-1636.
    • (2003) Journal Clinical Oncology , vol.21 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3
  • 19
    • 0029787294 scopus 로고    scopus 로고
    • Dichotomy of astrocytoma migration and proliferation
    • A. Giese, M.A. Loo, N. Tran et al., Dichotomy of astrocytoma migration and proliferation, International Journal of Cancer 67 (1996), 275-282.
    • (1996) International Journal of Cancer , vol.67 , pp. 275-282
    • Giese, A.1    Loo, M.A.2    Tran, N.3
  • 20
    • 0030056968 scopus 로고    scopus 로고
    • Cell adhesion: The molecular basis of tissue architecture and morphogenesis
    • B.M. Gumbiner, Cell adhesion: the molecular basis of tissue architecture and morphogenesis, Cell 84 (1996), 345-357.
    • (1996) Cell , vol.84 , pp. 345-357
    • Gumbiner, B.M.1
  • 21
    • 13444294190 scopus 로고    scopus 로고
    • Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets
    • D.B. Hoelzinger, L. Mariani, J. Weis et al., Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets, Neoplasia 7 (2005), 7-16.
    • (2005) Neoplasia , vol.7 , pp. 7-16
    • Hoelzinger, D.B.1    Mariani, L.2    Weis, J.3
  • 22
    • 0033408362 scopus 로고    scopus 로고
    • Cell adhesion: Old and new questions
    • R.O. Hynes, Cell adhesion: old and new questions, Trends in Genetics 15 (1999), M33-M37.
    • (1999) Trends in Genetics , vol.15
    • Hynes, R.O.1
  • 25
    • 3142514670 scopus 로고    scopus 로고
    • Progress in the development of nucleic acid therapeutics for cancer
    • A. Kalota, Progress in the development of nucleic acid therapeutics for cancer, Cancer Biology & Therapy 3 (2004), 4-12.
    • (2004) Cancer Biology & Therapy , vol.3 , pp. 4-12
    • Kalota, A.1
  • 26
    • 33646892664 scopus 로고    scopus 로고
    • Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and β1 integrin to promote cell migration
    • P.A. Kiely, D. O'Gorman, K. Luong et al., Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and β1 integrin to promote cell migration, Molecular and Cellular Biology 26 (2006), 4041-4051.
    • (2006) Molecular and Cellular Biology , vol.26 , pp. 4041-4051
    • Kiely, P.A.1    O'Gorman, D.2    Luong, K.3
  • 27
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • F. Lefranc, J. Brotchi and R. Kiss, Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis, Journal of Clinical Oncology 23 (2006), 2411-2422.
    • (2006) Journal of Clinical Oncology , vol.23 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 28
    • 0033942010 scopus 로고    scopus 로고
    • Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene
    • A. Li, S. Sakaguchi, R. Atarashi et al., Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene, Cellular and Molecular Neurobiology 20 (2000), 553-567.
    • (2000) Cellular and Molecular Neurobiology , vol.20 , pp. 553-567
    • Li, A.1    Sakaguchi, S.2    Atarashi, R.3
  • 29
    • 34047226825 scopus 로고    scopus 로고
    • Aberrant regulation of messenger RNA 3′-untraslated region in human cancer
    • I. Lopez de Silanes, M.P. Quesada and M. Esteller, Aberrant regulation of messenger RNA 3′-untraslated region in human cancer, Cellular Oncology 29 (2007), 1-17.
    • (2007) Cellular Oncology , vol.29 , pp. 1-17
    • Lopez de Silanes, I.1    Quesada, M.P.2    Esteller, M.3
  • 30
    • 34547122001 scopus 로고    scopus 로고
    • The 2007 WHO classification of tumours of the central nervous system
    • D.N. Louis, H. Ohgaki, O.D. Wiestler et al., The 2007 WHO classification of tumours of the central nervous system, Acta Neuropathologica 114 (2007), 97-109.
    • (2007) Acta Neuropathologica , vol.114 , pp. 97-109
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3
  • 32
    • 0034634395 scopus 로고    scopus 로고
    • The evolutionary fate and consequences of duplicate genes
    • M. Lynch and S. Conery, The evolutionary fate and consequences of duplicate genes, Science 290 (2000), 1151-1155.
    • (2000) Science , vol.290 , pp. 1151-1155
    • Lynch, M.1    Conery, S.2
  • 33
    • 0036925662 scopus 로고    scopus 로고
    • Genomic characterization of the human prion protein (PrP) gene locus
    • E. Makrinou, J. Collinge and M. Antoniou, Genomic characterization of the human prion protein (PrP) gene locus, Mammalian Genome 13 (2002), 696-703.
    • (2002) Mammalian Genome , vol.13 , pp. 696-703
    • Makrinou, E.1    Collinge, J.2    Antoniou, M.3
  • 34
    • 0035812297 scopus 로고    scopus 로고
    • The prion gene complex encoding PrPC and Doppel insights from mutational analysis
    • P. Mastrangelo and D. Westaway, The prion gene complex encoding PrPC and Doppel insights from mutational analysis, Gene 275 (2001), 1-18.
    • (2001) Gene , vol.275 , pp. 1-18
    • Mastrangelo, P.1    Westaway, D.2
  • 35
    • 16644362919 scopus 로고    scopus 로고
    • Specific gene suppression using antisense strategy for growth suppression of glioma
    • A. Matsuno and T. Nagashima, Specific gene suppression using antisense strategy for growth suppression of glioma, Medical Electron Microscopy 37 (2004), 158-161.
    • (2004) Medical Electron Microscopy , vol.37 , pp. 158-161
    • Matsuno, A.1    Nagashima, T.2
  • 36
    • 0034714488 scopus 로고    scopus 로고
    • Examination of the human prion protein-like gene Doppel for genetic susceptibility to sporadic and variant Creutzfeldt-Jakob disease
    • S. Mead, J. Beck, A. Dickinson et al., Examination of the human prion protein-like gene Doppel for genetic susceptibility to sporadic and variant Creutzfeldt-Jakob disease, Neuroscience Letters 290 (2000), 117-120.
    • (2000) Neuroscience Letters , vol.290 , pp. 117-120
    • Mead, S.1    Beck, J.2    Dickinson, A.3
  • 37
    • 5044224775 scopus 로고    scopus 로고
    • molecular classification for therapy
    • DNA-microarray analysis of brain cancer
    • P.S. Mischel, T.F. Cloughesy and S.F. Nelson, DNA-microarray analysis of brain cancer: molecular classification for therapy, Nature Review Neuroscience 5 (2004), 782-792.
    • (2004) Nature Review Neuroscience , vol.5 , pp. 782-792
    • Mischel, P.S.1    Cloughesy, T.F.2    Nelson, S.F.3
  • 38
    • 0033215478 scopus 로고    scopus 로고
    • Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
    • R.C. Moore, I.Y. Lee, G.L. Silverman et al., Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel, Journal of Molecular Biology 292 (1999), 797-817.
    • (1999) Journal of Molecular Biology , vol.292 , pp. 797-817
    • Moore, R.C.1    Lee, I.Y.2    Silverman, G.L.3
  • 40
    • 34250877865 scopus 로고    scopus 로고
    • Genetic pathways to primary and secondary glioblastoma
    • H. Ohgaki and P. Kleihues, Genetic pathways to primary and secondary glioblastoma, American Journal of Pathology 170 (2007), 1445-1453.
    • (2007) American Journal of Pathology , vol.170 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 41
    • 0037044714 scopus 로고    scopus 로고
    • The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa
    • K. Peoc'h, C. Serres, Y. Frobert et al., The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa, Journal of Biological Chemistry 277 (2002), 43071-43078.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 43071-43078
    • Peoc'h, K.1    Serres, C.2    Frobert, Y.3
  • 43
    • 0020321767 scopus 로고
    • Novel proteinaceous infectious particles cause scrapie
    • S.B. Prusiner, Novel proteinaceous infectious particles cause scrapie, Science 216 (1982), 136-144.
    • (1982) Science , vol.216 , pp. 136-144
    • Prusiner, S.B.1
  • 44
  • 47
    • 47749118046 scopus 로고    scopus 로고
    • Altered cellular distribution and sub-cellular sorting of doppel (Dpl) protein in human astrocytoma cell lines
    • E. Sbalchiero, A. Azzalin, S. Palumbo et al., Altered cellular distribution and sub-cellular sorting of doppel (Dpl) protein in human astrocytoma cell lines, Cellular Oncology 30 (2008), 337-347.
    • (2008) Cellular Oncology , vol.30 , pp. 337-347
    • Sbalchiero, E.1    Azzalin, A.2    Palumbo, S.3
  • 48
    • 0035474310 scopus 로고    scopus 로고
    • Adaptor proteins in protein kinase C-mediated signal transduction
    • D. Schechtman and D. Mochly-Rosen, Adaptor proteins in protein kinase C-mediated signal transduction, Oncogene 20 (2001), 6339-6347.
    • (2001) Oncogene , vol.20 , pp. 6339-6347
    • Schechtman, D.1    Mochly-Rosen, D.2
  • 49
    • 2942585676 scopus 로고    scopus 로고
    • Effective intracellular delivery of oligonucleotides in order to make sense of antisense
    • F. Shi and D. Hoekstra, Effective intracellular delivery of oligonucleotides in order to make sense of antisense, Journal of Controlled Release 97 (2004), 189-209.
    • (2004) Journal of Controlled Release , vol.97 , pp. 189-209
    • Shi, F.1    Hoekstra, D.2
  • 50
    • 33645563620 scopus 로고    scopus 로고
    • Antisense therapy in malignant diseases: Status quo and quo vadis?
    • I. Tamm, Antisense therapy in malignant diseases: status quo and quo vadis?, Clinical Science 110 (2006), 427-442.
    • (2006) Clinical Science , vol.110 , pp. 427-442
    • Tamm, I.1
  • 51
    • 0035021524 scopus 로고    scopus 로고
    • The PrP-like protein doppel gene in sheep and cattle: CDNA sequence and expression
    • M.A. Tranulis, A. Espenes, S. Comincini et al., The PrP-like protein doppel gene in sheep and cattle: cDNA sequence and expression, Mammalian Genome 12 (2001), 376-379.
    • (2001) Mammalian Genome , vol.12 , pp. 376-379
    • Tranulis, M.A.1    Espenes, A.2    Comincini, S.3
  • 52
    • 0036184716 scopus 로고    scopus 로고
    • Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease
    • N.L. Tuzi, E. Gall, D. Melton et al., Expression of doppel in the CNS of mice does not modulate transmissible spongiform encephalopathy disease, Journal of General Virology 83 (2002), 705-711.
    • (2002) Journal of General Virology , vol.83 , pp. 705-711
    • Tuzi, N.L.1    Gall, E.2    Melton, D.3
  • 53
    • 28744449922 scopus 로고    scopus 로고
    • Prion-like doppel gene (PRND) in the goat: Genomic structure, cDNA, and polymorphisms
    • C. Uboldi, I. Del Vecchio, M.G. Foti et al., Prion-like doppel gene (PRND) in the goat: genomic structure, cDNA, and polymorphisms, Mammalian Genome 16 (2005), 963-971.
    • (2005) Mammalian Genome , vol.16 , pp. 963-971
    • Uboldi, C.1    Del Vecchio, I.2    Foti, M.G.3
  • 54
    • 27744577845 scopus 로고    scopus 로고
    • Cell migration and invasion assays
    • A. Valster, N.L. Tran, M. Nakada et al., Cell migration and invasion assays, Methods 37 (2005), 208-215.
    • (2005) Methods , vol.37 , pp. 208-215
    • Valster, A.1    Tran, N.L.2    Nakada, M.3
  • 56
    • 0033615415 scopus 로고    scopus 로고
    • Perspectives: Neurobiology. PrP's double causes trouble
    • C. Weissmann and A. Aguzzi, Perspectives: neurobiology. PrP's double causes trouble, Science 286 (1999), 914-915.
    • (1999) Science , vol.286 , pp. 914-915
    • Weissmann, C.1    Aguzzi, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.