Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells: A glucose-dependent action via inhibition of ATP-sensitive K+-channels

Diabetes, Obesity and Metabolism

Volumn 10, Issue 11, 2008, Pages 1074-1085

  Abudula, R ^a   Matchkov, V V ^b   Jeppesen, Per Bendix ^a   Nilsson, H ^b   Aalkjaer C ^b   Hermansen, K ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

2 O beta glucosyl 13 O beta sophorosyl 19 O beta glucosyl steviol cAMP; ATP ADP; Glucose; Insulin; MIN6 cells; Mouse islets; Rebaudioside A; Stevioside; Sulfonylureas

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CYCLIC AMP; GLUCOSE; GLYCOSIDE; INSULIN; REBAUDIOSIDE A; STEVIOSIDE; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL ISOLATION; CELL LINE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ELECTROPHYSIOLOGY; HYPOGLYCEMIA; INHIBITION KINETICS; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATCH CLAMP; RADIOIMMUNOASSAY; SIGNAL TRANSDUCTION;

EID: 54249120793     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2008.00864.x     Document Type: Article

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