Rhabdomyosarcomas in adults: classification and differential diagnosis

Diagnostic Histopathology

Volumn 14, Issue 11, 2008, Pages 538-545

  Nascimento, Alessandra F ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

adults; alveolar; embryonal; pleomorphic; rhabdomyosarcoma; sarcoma; sclerosing; spindle cell

Indexed keywords

CYCLOPHOSPHAMIDE; DACTINOMYCIN; DESMIN; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; VINCRISTINE;

ARTICLE; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CELL DIFFERENTIATION; DIFFERENTIAL DIAGNOSIS; EMBRYONAL RHABDOMYOSARCOMA; HISTOLOGY; HUMAN; MULTIMODALITY CANCER THERAPY; PEDIATRICS; PROGNOSIS; RHABDOMYOSARCOMA; SKELETAL MUSCLE; SPINDLE CELL SARCOMA;

EID: 54249120331     PISSN: 17562317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mpdhp.2008.08.003     Document Type: Article

References (48)

1. In: Fletcher C.D.M., Unni K.K., and Mertens F. (Eds). Pathology & Genetics of Tumors of Soft Tissue and Bone (2002), IARC Press, Lyon
2. Gurney J.G., Davis S., Severson R.K., Fang J.Y., Ross J.A., and Robison L.L. Trends in cancer incidence among children in the U.S. Cancer 78 (1996) 532-541
3. Walterhouse D., and Watson A. Optimal management strategies for rhabdomyosarcoma in children. Paediatr Drugs 9 (2007) 391-400
4. D'Amore E.S., Tollot M., Stracca-Pansa V., et al. Therapy associated differentiation in rhabdomyosarcomas. Mod Pathol 7 (1994) 69-75
5. Coffin C.M., Rulon J., Smith L., Bruggers C., and White F.V. Pathologic features of rhabdomyosarcoma before and after treatment: a clinicopathologic and immunohistochemical analysis. Mod Pathol 10 (1997) 1175-1187
6. Kodet R, Newton WA Jr., Hamoudi AB, Asmar L, Jacobs DL, Maurer HM. Childhood rhabdomyosarcoma with anaplastic (pleomorphic) features. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 1993;17:443-453.
7. Koufos A., Hansen M.F., Copeland N.G., Jenkins N.A., Lampkin B.C., and Cavenne W.K. Loss of heterozygosity in three embryonal tumours suggest a common pathogenic mechanism. Nature 316 (1985) 330-334
8. Anderson J., Gordon A., McManus A., Shipley J., and Pritchard-Jones K. Disruption of imprinted genes at chromosome region 11p15.5 in paediatric rhabdomyosarcoma. Neoplasia 1 (1999) 340-348
9. Barr F.G., Galili N., Holick J., Biegel J.A., Rovera G., and Emanuel B.S. Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet 3 (1993) 113-117
10. Galili N., Davis R.J., Fredericks W.J., et al. Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nature Genet 5 (1993) 230-235
11. Davis R.J., D'Cruz C.M., Lovell M.A., Biegel J.A., and Barr F.G. Fusion of PAX7 to FKHR by the variant t(1;13) (p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res 54 (1994) 2869-2872
12. Bennicelli J.L., Edwards R.H., and Barr F.G. Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma. Proc Natl Acad Sci U S A 93 (1996) 5455-5459
13. Bennicelli J.L., Advani S., Schafer B.W., and Barr F.G. PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma. Oncogene 18 (1999) 4348-4356
14. Furlong M.A., and Fanburg-Smith J.C. Pleomorphic rhabdomyosarcoma in children: four cases in the pediatric age group. Ann Diagn Pathol 5 (2001) 199-206
15. La Quaglia M.P., Heller G., Ghavimi F., et al. The effect of age at diagnosis on outcome in rhabdomyosarcoma. Cancer 73 (1994) 109-117
16. Hawkins W.G., Hoos A., Antonescu C.R., et al. Clinicopathologic analysis of patients with adult rhabdomyosarcoma. Cancer 91 (2001) 794-803
17. Esnaola N.F., Rubin B.P., Baldini E.H., et al. Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg 234 (2001) 215-223
18. Ariel I.M., and Briceno M. Rhabdomyosarcoma of the extremities and trunk: analysis of 150 patients treated by resection. J Surg Oncol 7 (1975) 269-287
19. Little D.J., Ballo M.T., Zagars G.K., et al. Adult rhabdomyosarcoma. Outcome following multimodality treatment. Cancer 95 (2002) 377-388
20. Furlong M.A., Mentzel T., and Fanburg-Smith J.C. Pleomorphic rhabdomyosarcoma in adults: a clinicopathologic study of 38 cases with emphasis on morphologic variants and recent skeletal muscle-specific markers. Mod Pathol 14 (2001) 595-603
21. Kumar S., Perlman E., Harris C.A., Raffeld M., and Tsokos M. Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissues. Mod Pathol 13 (2000) 988-993
22. Morotti R.A., Nicol K.K., Parham D.M., et al. An immunohistochemical algorithm to facilitate diagnosis and subtyping of rhabdomyosarcoma: the Children's Oncology Group experience. Am J Surg Pathol 30 (2006) 962-968
23. Cessna M.H., Zhou H., Perkins S.L., et al. Are myogenin and myoD1 expression specific for rhabdomyosarcoma? A study of 150 cases, with emphasis on spindle cell mimics. Am J Surg Pathol 25 (2001) 1150-1157
24. Mitelman Database of Chromosome Aberrations in Cancer (2007). http://cgap.nci.nih.gov/Chromosomes/Mitelman
25. Oda Y., Miyajima K., Kawaguchi K., et al. Pleomorphic leiomyosarcoma: clinicopathologic and immunohistochemical study with special emphasis on its distinction from ordinary leiomyosarcoma and malignant fibrous histiocytoma. Am J Surg Pathol 25 (2001) 1030-1038
26. Gebhard S., Coindre J.M., Michels J.J., et al. Pleomorphic liposarcoma: clinicopathologic, immunohistochemical, and follow-up analysis of 63 cases: a study from the French Federation of Cancer Centers Sarcoma Group. Am J Surg Pathol 26 (2002) 601-616
27. Hornick J.L., Bosenberg M.W., Mentzel T., McMenamin M.E., Oliveira A.M., and Fletcher C.D. Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases. Am J Surg Pathol 28 (2004) 1257-1267
28. Cavazzana A.O., Schmidt D., Ninfo V., et al. Spindle cell rhabdomyosarcoma. A prognostically favorable variant of rhabdomyosarcoma. Am J Surg Pathol 16 (1992) 229-235
29. Rubin B.P., Hasserjian R.P., Singer S., Janecka I., Fletcher J.A., and Fletcher C.D. Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis. Am J Surg Pathol 22 (1998) 459-464
30. Nascimento A.F., and Fletcher C.D. Spindle cell rhabdomyosarcoma in adults. Am J Surg Pathol 29 (2005) 1106-1113
31. Mentzel T., and Kuhnen C. Spindle cell rhabdomyosarcoma in adults: clinicopathological and immunohistochemical analysis of seven new cases. Virchows Arch 449 (2006) 554-560
32. Mentzel T., and Katenkamp D. Sclerosing, pseudovascular rhabdomyosarcoma in adults. Clinicopathological and immunohistochemical analysis of three cases. Virchows Arch 436 (2000) 305-311
33. Folpe A.L., McKenney J.K., Bridge J.A., and Weiss S.W. Sclerosing rhabdomyosarcoma in adults: report of four cases of a hyalinizing, matrix-rich variant of rhabdomyosarcoma that may be confused with osteosarcoma, chondrosarcoma, or angiosarcoma. Am J Surg Pathol 26 (2002) 1175-1183
34. Chiles M.C., Parham D.Q., Qualman S.J., et al. Sclerosing rhabdomyosarcomas in children and adolescents: a clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group. Pediatr Dev Pathol 7 (2004) 583-594
35. Croes R., Debiec-Rychter M., Cokelaere K., De Vos R., Hagemeijer A., and Sciot R. Adult sclerosing rhabdomyosarcoma: cytogenetic link with embryonal rhabdomyosarcoma. Virchows Arch 446 (2005) 64-67
36. Maurer H.M., Beltangady M., Gehan E.A., et al. The Intergroup Rhabdomyosarcoma Study-I. A final report. Cancer 61 (1988) 209-220
37. Binh M.D., Guillou L., Hostein L., et al. Dedifferentiated liposarcomas with divergent myosarcomatous differentiation developed in the internal trunk: a study of 27 cases and comparison to conventional dedifferentiated liposarcomas and leiomyosarcomas. Am J Surg Pathol 31 (2007) 1557-1566
38. Binh M.D., Sastre-Garau X., Guillou L., et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol 29 (2005) 1340-1347
39. Ducatman B.S., and Scheithauer B.W. Malignant peripheral nerve sheath tumor with divergent differentiation. Cancer 54 (1984) 1049-1057
40. Hruban R.H., Shiu M.H., Senie R.T., and Woodruff J.M. Malignant peripheral nerve sheath tumors of the buttock and lower extremity. A study of 43 cases. Cancer 66 (1990) 1253-1269
41. Woodruff J.M., and Perino G. Non-germ cell or teratomatous malignant tumors showing additional rhabdomyoblastic differentiation, with emphasis on the malignant Triton tumor. Semin Diagn Pathol 11 (1994) 69-81
42. Silverberg S.G., Major F.J., Blessing J.A., et al. Carcinosarcoma (malignant mixed mesodermal tumor) of the uterus. A Gynecologic Oncology Group pathologic study of 203 cases. Int J Gynecol Pathol 9 (1990) 1-19
43. Perret L., Chaubert P., Hessler D., and Guillou L. Primary heterologous carcinosarcoma (metaplastic carcinoma) of the urinary bladder: a clinicopathologic, immunohistochemical, and ultrastructural analysis of eight cases and a review of the literature. Cancer 82 (1998) 1535-1549
44. Patel N.K., McKee P.H., Smith N.P., and Fletcher C.D. Primary metaplastic carcinoma (carcinosarcoma) of the skin. A clinicopathologic study of four cases and review of the literature. Am J Dermatopathol 19 (1997) 363-372
45. Carda C., Ferrer J., Vilanova M., Peydro A., and Llombart-Bosch A. Anaplastic carcinoma of the thyroid with rhabdomyosarcomatous differentiation: a report of two cases. Virchows Arch 446 (2005) 46-51
46. Koss M.N., Hochholzer L., and Frommelt R.A. Carcinosarcomas of the lung: a clinicopathologic study of 66 patients. Am J Surg Pathol 23 (1999) 1514-1526
47. Motzer R.J., Amsterdam A., Pietro V., et al. Teratoma with malignant transformation: diverse malignant histologies arising in men with germ cell tumors. J Urol 159 (1998) 133-138
48. Malagón H.D., Valdez A.M.C., Moran C.A., and Suster S. Germ cell tumors with sarcomatous components. A clinicopathologic and immunohistochemical study of 46 cases. Am J Surg Pathol 31 (2007) 1356-1362